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Volumn 282, Issue 1-2, 2000, Pages 69-72

Insulin-like growth factor-1-mediated protection from neuronal apoptosis is linked to phosphorylation of the pro-apoptotic protein BAD but not to inhibition of cytochrome c translocation in rat cerebellar neurons

Author keywords

Akt kinase; Apoptosis; BAD; Cerebellar granule neurons; Phosphorylation; PI 3 kinase; Posttranscriptional modification

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLOHEXIMIDE; CYTOCHROME C; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN BAD; SOMATOMEDIN C; WORTMANNIN;

EID: 0034677861     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)00857-0     Document Type: Article
Times cited : (37)

References (20)
  • 3
    • 0031054670 scopus 로고    scopus 로고
    • Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: Possible involvement of PI-3 kinase in IGF-1 signaling
    • D'Mello S.R., Borodezt K., Soltoff S.P. Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI-3 kinase in IGF-1 signaling. J. Neurosci. 17:1997;1548-1560.
    • (1997) J. Neurosci. , vol.17 , pp. 1548-1560
    • D'Mello, S.R.1    Borodezt, K.2    Soltoff, S.P.3
  • 4
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:1997;231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 5
    • 0032192529 scopus 로고    scopus 로고
    • Evidence of a novel event during neuronal cell death: Development of competence-to-die in response to cytoplasmic cytochrome c
    • Deshmukh M., Johnson E.M. Jr. Evidence of a novel event during neuronal cell death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron. 21:1998;695-705.
    • (1998) Neuron , vol.21 , pp. 695-705
    • Deshmukh, M.1    Johnson E.M., Jr.2
  • 7
    • 0031820341 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: Cytochrome c release in the absence of altered expression of Bcl-2 family proteins
    • Gleichmann M., Beinroth S., Reed J.C., Krajewski S., Schulz J.B., Wüllner U., Klockgether T., Weller M. Potassium deprivation-induced apoptosis of cerebellar granule neurons: cytochrome c release in the absence of altered expression of Bcl-2 family proteins. Cell. Physiol. Biochem. 8:1998;194-201.
    • (1998) Cell. Physiol. Biochem. , vol.8 , pp. 194-201
    • Gleichmann, M.1    Beinroth, S.2    Reed, J.C.3    Krajewski, S.4    Schulz, J.B.5    Wüllner, U.6    Klockgether, T.7    Weller, M.8
  • 8
    • 0032515874 scopus 로고    scopus 로고
    • Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
    • Hu Y., Benedict M.A., Wu D., Inohara N., Nunez G. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc. Natl. Acad. Sci. USA. 95:1998;4386-4391.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 4386-4391
    • Hu, Y.1    Benedict, M.A.2    Wu, D.3    Inohara, N.4    Nunez, G.5
  • 9
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 10
    • 0030797727 scopus 로고    scopus 로고
    • Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
    • Miller T.M., Moulder K.L., Knudson C.M., Creedon D.J., Deshmukh M., Korsmeyer S.J., Johnson E.M. Jr. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J. Cell Biol. 139:1997;205-217.
    • (1997) J. Cell Biol. , vol.139 , pp. 205-217
    • Miller, T.M.1    Moulder, K.L.2    Knudson, C.M.3    Creedon, D.J.4    Deshmukh, M.5    Korsmeyer, S.J.6    Johnson E.M., Jr.7
  • 11
    • 0030938816 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- And insulin-like growth factor I-mediated survival of cerebellar granule cells
    • Miller T.M., Tansey M.G., Johnson E.M. Jr., Creedon D.J. Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells. J. Biol. Chem. 272:1997;9847-9853.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9847-9853
    • Miller, T.M.1    Tansey, M.G.2    Johnson E.M., Jr.3    Creedon, D.J.4
  • 12
    • 0030828019 scopus 로고    scopus 로고
    • Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: Prevention of caspase activation and reduced production of reactive oxygen species
    • Schulz J.B., Bremen D., Reed J.C., Lommatzsch J., Takayama S., Wüllner U., Löschmann P.A., Klockgether T., Weller M. Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: Prevention of caspase activation and reduced production of reactive oxygen species. J. Neurochem. 69:1997;2075-2086.
    • (1997) J. Neurochem. , vol.69 , pp. 2075-2086
    • Schulz, J.B.1    Bremen, D.2    Reed, J.C.3    Lommatzsch, J.4    Takayama, S.5    Wüllner, U.6    Löschmann, P.A.7    Klockgether, T.8    Weller, M.9
  • 13
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis
    • Schulz J.B., Weller M., Klockgether T. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis. ICE-like protease activity, and reactive oxygen species, J. Neurosci. 16:1996;4696-4706.
    • (1996) ICE-like Protease Activity, and Reactive Oxygen Species, J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 14
    • 0030753359 scopus 로고    scopus 로고
    • Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons
    • Shimoke K., Kubo T., Numakawa T., Abiru Y., Enokido Y., Takei N., Ikeuchi T., Hatanaka H. Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons. Dev. Brain Res. 101:1997;197-206.
    • (1997) Dev. Brain Res. , vol.101 , pp. 197-206
    • Shimoke, K.1    Kubo, T.2    Numakawa, T.3    Abiru, Y.4    Enokido, Y.5    Takei, N.6    Ikeuchi, T.7    Hatanaka, H.8
  • 15
    • 0031978372 scopus 로고    scopus 로고
    • Neurotrophins rescue cerebellar granule neurons from oxidative stress- mediated apoptotic death: Selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway
    • Skaper S.D., Floreani M., Negro A., Facci L., Giusti P. Neurotrophins rescue cerebellar granule neurons from oxidative stress- mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. J. Neurochem. 70:1998;1859-1868.
    • (1998) J. Neurochem. , vol.70 , pp. 1859-1868
    • Skaper, S.D.1    Floreani, M.2    Negro, A.3    Facci, L.4    Giusti, P.5
  • 16
    • 0030888097 scopus 로고    scopus 로고
    • Susceptibility of cerebellar granule neurons derived from Bcl-2- deficient and transgenic mice to cell death
    • Tanabe H., Eguchi Y., Kamada S., Martinou J.C., Tsujimoto Y. Susceptibility of cerebellar granule neurons derived from Bcl-2- deficient and transgenic mice to cell death. Eur. J. Neurosci. 9:1997;848-856.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 848-856
    • Tanabe, H.1    Eguchi, Y.2    Kamada, S.3    Martinou, J.C.4    Tsujimoto, Y.5
  • 18
    • 0031972678 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
    • Watson A., Eilers A., Lallemand D., Kyriakis J., Rubin L.L., Ham J. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J. Neurosci. 18:1998;751-762.
    • (1998) J. Neurosci. , vol.18 , pp. 751-762
    • Watson, A.1    Eilers, A.2    Lallemand, D.3    Kyriakis, J.4    Rubin, L.L.5    Ham, J.6
  • 19
    • 0026463018 scopus 로고
    • Niacinamide blocks 3-acetylpridine toxicity of cerebellar granule cells in vitro
    • Weller M., Marini A.M., Paul S.M. Niacinamide blocks 3-acetylpridine toxicity of cerebellar granule cells in vitro. Brain Res. 594:1992;160-164.
    • (1992) Brain Res. , vol.594 , pp. 160-164
    • Weller, M.1    Marini, A.M.2    Paul, S.M.3
  • 20
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-x(L)
    • Zha J.P., Harada H., Yang E., Jockel J., Korsmeyer S.J. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-x(L). Cell. 87:1996;619-628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.P.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.