Neuronal nitric oxide synthase (nNOS) mRNA is down-regulated, and constitutive NOS enzymatic activity decreased, in thoracic dorsal root ganglia and spinal cord of the rat by a substance P N-terminal metabolite

European Journal of Neuroscience

Volumn 14, Issue 4, 2001, Pages 577-584

  Kovacs, Katalin J ^a   Cai, Yongjiu ^a   Larson, Alice A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Arginine; Citrulline; Hyperalgesia; Pain; Writhing

Indexed keywords

ACETIC ACID; CAPSAICIN; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; SUBSTANCE P [1-7]; ARGININE; PEPTIDE FRAGMENT; SUBSTANCE P; SUBSTANCE P (1-7);

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; HYPERALGESIA; LUMBAR SPINAL CORD; MALE; MUSCLE SPINDLE AFFERENT NERVE; NEWBORN; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD; SPINAL GANGLION; THORACIC SPINAL CORD; WRITHING TEST; ANIMAL; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; LUMBAR VERTEBRA; METABOLISM; NERVE DEGENERATION; NERVE FIBER; PAIN RECEPTOR; PATHOLOGY; PATHOPHYSIOLOGY; SENSORY NERVE CELL; SPRAGUE DAWLEY RAT; VERTEBRA;

ANIMALS; ARGININE; CAPSAICIN; GANGLIA, SPINAL; LUMBAR VERTEBRAE; MALE; NERVE DEGENERATION; NERVE FIBERS; NEURONS, AFFERENT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOCICEPTORS; PAIN; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPINAL CORD; SUBSTANCE P; THORACIC VERTEBRAE;

EID: 0036279972     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01675.x     Document Type: Article

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