Mutual antagonism between nerve growth factor and substance P N-terminal activity on nociceptive activity in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 3, 1997, Pages 1345-1350

  Larson, Alice A ^a   Kitto, Kelley F ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; SUBSTANCE P; SUBSTANCE P ANTAGONIST; SUBSTANCE P DERIVATIVE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG SELECTIVITY; ETIOLOGY; HYPERALGESIA; INTRATHECAL DRUG ADMINISTRATION; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; TAIL FLICK TEST;

ANALGESICS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; MALE; MICE; NERVE GROWTH FACTORS; PEPTIDE FRAGMENTS; SUBSTANCE P;

EID: 0030885305     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. BUCK, S. AND BURKS, T. F.: The neuropharmacology of capsaicin: Review of some recent observations. Pharmacol. Rev. 38: 179-226, 1986.
2. CRIDLAND, R. A. AND HENRY, J. L.: N-and C-terminal fragments of substance P: Spinal effects in the rat tail flick test. Brain Res. Bull. 20: 429-432, 1988.
3. DUGGAN, A. W., HENDRY, I. A., MORTON, C. R., HUTCHINSON, W. D. AND ZHAO, Z. Q.: Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res. 451: 261-273, 1988.
4. GAMSE, R., LACKNER, D., GAMSE, G. AND LEEMAN, S. E.: Effect of capsaicin pretreatment on capsaicin-evoked release of immunoreactive somatostatin and substance P from primary sensory neurons. Arch. Pharmacol. 316: 38-41, 1981.
5. GOETTL, V. M. AND LARSON, A. A.: Activity at phencyclidine and mu opioid sites mediates the hyperalgesic and antinociceptive properties of the N-terminus of substance P in a model of visceral pain. Neuroscience 60: 375-382, 1994.
6. GOETTL, V. M. AND LARSON, A. A.: Nitric oxide mediates long-term hyperalgesic and antinociceptive effects of the N-terminus of substance P in the formalin assay in mice. Pain 67: 2-3, 1996.
7. 3H]proline incorporation in vitro. Neuroscience 6: 1917-1919, 1981.
8. 2-terminus of substance P modulates NMDA-induced activity in the mouse spinal cord. J. Neurosci. 14: 3364-3369, 1994.
9. IGWE, O. J., KIM, D. C., SEYBOLD, V. S. AND LARSON, A. A.: Specific binding of substance P amino terminal heptapeptides [SP(1-7)] to mouse brain and spinal cord membranes. J. Neurosci. 10: 3653-3663, 1990a.
10. IGWE, O. J., SUN, X. AND LARSON, A. A.: Role of substance P amino terminal metabolites in substance P-induced desensitization in adult mice. Neuroscience 36: 535-542, 1990b.
11. KANTNER, R. M., KIRBY, M. L. AND GOLDSTETN, B. D.: Increase in substance P in the dorsal horn during a chemogenic nociceptive stimulus. Brain Res. 338: 196-199, 1985.
12. KANTNER, R. M., GOLDSTEIN, B. D. AND KIRBY, M. L.: Regulatory mechanisms for substance P in the dorsal horn during a nociceptive stimulus: Axoplasmic transport vs electrical activity. Brain Res. 385: 282-290, 1986.
13. KESSLER, J. A. AND BLACK, I. B.: Nerve growth factor stimulates the development of substance P in sensory ganglia. Proc. Natl. Acad. Sci. U.S.A. 77: 649-652, 1980.
14. KREEGER, J. S., KITTO, K. F. AND LARSON, A. A.: Substance P N-terminal metabolites and nitric oxide mediate capsaicin-induced antinociception in the adult mouse. J. Pharmacol. Exp. Ther. 271: 1281-1285, 1994.
15. LARSON, A. A. AND SUN, X.: Amino terminus of substance P potentiates kainic acid-induced activity in the mouse spinal cord. J. Neurosci. 12: 4905-4910, 1992.
16. 2-terminus of substance P in the inhibition by capsaicin of behavioral sensitization to kainic acid-induced activity in the adult mouse. J. Pharmacol. Exp. Ther. 268: 366-371, 1994.
17. LEWIN, G. R. AND MENDELL, L. M.: NGF and nociception. Trends Neurosci. 16: 353-359, 1993.
18. LEWIN, G. R., RITTER, A. M. AND MENDELL, L. M.: Nerve growth factor-induced hyperalgesia in the neonatal and adult rat. J. Neurosci. 13: 2136-2148, 1993.
19. LINDSAY, R. M. AND HARMAR, A. J.: Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons. Nature (Lond.) 337: 362-364, 1989.
20. LINDSAY, R. M., LOCKETT, C., STERNBERG, J. AND WINTER, J.: Neuropeptide expression in cultures of adult sensory neurons: modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor. Neuroscience 33: 53-65, 1989.
21. LIU, H., WANG, H., SHENG, M., JAN, L. Y., JAN Y. N. AND BASBAUM, A. I.: Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn. Proc. Natl. Acad. Sci. U.S.A. 91: 8383-8387, 1994.
22. MILLER, M. S., BUCK, S. H., SIPES, I. G., YAMAMURA, H. I. AND BURKS, F. F.: Regulation of substance P by nerve growth factor: Disruption by capsaicin. Brain Res. 250: 193-196, 1982.
23. MOUSSEAU, D. D., SUN, X. AND LARSON, A. A.: Identification of a novel receptor mediating substance P-induced behavior in the mouse. Eur. J. Pharmacol. 217: 197-201, 1992.
24. 2-terminus of substance P. J. Pharmacol. Exp. Ther. 268: 785-790, 1994.
25. NYBERG, F., LEGREVES, P., SUNDQUIST, C. AND TERENIUS, L.: Characterization of substance P(1-7) and (1-8) generating enzyme in human cerebrospinal fluid. Biochem. Biophys. Res. Commun. 125: 244-250, 1984.
26. OTTEN, U., LOREZ, H. P. AND BUSINGER, F.: Nerve growth factor antagonizes the neurotoxic action of capsaicin on primary sensory neurones. Nature (Lond.) 301: 515-517, 1983.
27. RICH, K. M., YIP, H. K., OSBOURNE, P. A., SCHMIDT, R. E. AND JOHNSON, E. M.: Role of NGF in the adult dorsal root ganglia neuron and its response to injury. J. Comp. Neurol. 230: 110-118, 1984.
28. SAKURADA, T., LEGREVES, P., STEWART, J. AND TERENIUS, L.: Measurement of substance P metabolites in rat CNS. J. Neurochem. 44: 718-722, 1985.
29. SCHAIBLE, H. G., JARROT, B., HOPE, P. J. AND DUGGAN, A. W.: Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: A study with antibody microprobes. Brain Res. 529: 214-223, 1990.
30. SCHWARTZ, J. P., PEARSON, J. AND JOHNSON, E. M.: Effect of exposure to anti-NGF on sensory neurons of adult rats and guinea pigs. Brain Res. 244: 378-381, 1982.
31. SKILLING, S. R., SMULLIN, D. H., BEITZ, A. J. AND LARSON, A. A.: Extracellular amino acid concentrations in the dorsal spinal cord of freely moving rats following veratridine and nociceptive stimulation. J. Neurosci. 10: 1309-1318, 1988.
32. SKILLING, S. R., SMULLIN, D. H. AND LARSON, A. A.: Differential effects of C-and N-terminal substance P metabolites on the release of amino acid neurotransmitters from the spinal cord: potential role in nociception. J. Neurosci. 10: 1309-1318, 1990.
33. STEWART, J. M., HALL, M. E., HARKINS, J., FREDERICKSON, R. C. A. AND TERENIUS, L.: A fragment of substance P with specific central activity: SP(1-7). Peptides 3: 851-857, 1982.
34. TAYLOR, D. C. M., PIERAU, F.-K. AND SZOLCSANYI, J.: Long lasting inhibition of horseradish peroxidase (HRP) transport in sensory nerves induced by capsaicin treatment of the receptive field. Brain Res. 298: 45-49, 1984.
35. TAYLOR, D. C. M., PIERAU, F.-K. AND SZOLCSANYI, J.: Capsaicin-induced inhibition of axoplasmic transport is prevented by nerve growth factor. Cell Tissue Res. 240: 569-573, 1985.
36. VERGE, V. M. K., MERLIO, J.-P., GRODIN, J., ERNFORS, P., PERSSON, H., RIOPELLE, R. J., HOKFELT, T., RICHARDSON, P. M.: Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF. J. Neurosci. 12: 4011-4022, 1992.
37. WINTER, J., FORBES, C. A., STERNBERG, J. AND LINDSAY, R. M.: NGF Regulates adult rat cultured DRG neuron responses to the excitotoxin capsaicin. Neuron 1: 973-981, 1988.