An antagonist of substance P N-terminal fragments, D-substance P(1-7), reveals that both nociceptive and antinociceptive effects are induced by substance P N-terminal activity during noxious chemical stimulation

Brain Research

Volumn 780, Issue 1, 1998, Pages 80-85

  Goettl, Virginia M ^a   Larson, Alice A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Hyperalgesia; Intrathecal; Mouse; Pain; Substance P; Substance P fragment

Indexed keywords

SUBSTANCE P [1-7];

AMINO ACID METABOLISM; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; HYPERALGESIA; MOUSE; NEUROTRANSMITTER RELEASE; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; STIMULUS RESPONSE; TAIL FLICK TEST;

ANALYSIS OF VARIANCE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MICE; PAIN; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; STIMULATION, CHEMICAL; SUBSTANCE P;

EID: 0032484539     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01146-3     Document Type: Article

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