Protective effects of Brussels sprouts towards B[a]P-induced DNA damage: A model study with the single-cell gel electrophoresis (SCGE)/Hep G2 assay

Food and Chemical Toxicology

Volumn 40, Issue 8, 2002, Pages 1077-1083

  Laky, B ^a   Knasmuller S ^a   Gminski, R ^b   Mersch Sundermann, V ^b   Scharf, G ^a   Verkerk, R ^c   Freywald, C ^a   Uhl, M ^a   Kassie, F ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF TRIER   (Germany)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

AITC; B(a)P; Brussels sprouts; Chemoprevention; Comet assay; Hep G2 cells

Indexed keywords

ALLYL ISOTHIOCYANATE; BENZO[A]PYRENE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; BRUSSEL SPROUT EXTRACT; ETHOXYRESORUFIN DEETHYLASE; GLUCOSINOLATE; GLUTATHIONE TRANSFERASE; PLANT EXTRACT; SINIGRIN; UNCLASSIFIED DRUG;

ARTICLE; BRUSSELS SPROUT; CELL STRAIN HEPG2; CHEMOPROPHYLAXIS; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INDUCTION; GENOTOXICITY; HUMAN; HUMAN CELL;

ANIMALS; BENZO(A)PYRENE; BRASSICA; CARCINOMA, HEPATOCELLULAR; CYTOCHROME P-450 CYP1A1; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ELECTROPHORESIS, AGAR GEL; ENZYME ACTIVATION; GLUTATHIONE TRANSFERASE; HUMANS; ISOTHIOCYANATES; LIVER NEOPLASMS; MUTAGENICITY TESTS; PLANT EXTRACTS; TUMOR CELLS, CULTURED;

BRASSICA OLERACEA VAR. GEMMIFERA;

EID: 0036279573     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(02)00031-5     Document Type: Article

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