First and second transmembrane segments of α3, α4, β2, and β4 nicotinic acetylcholine receptor subunits influence the efficacy and potency of nicotine

Molecular Pharmacology

Volumn 61, Issue 6, 2002, Pages 1416-1422

  Rush, Ray ^a   Kuryatov, Alexander ^a   Nelson, Mark E ^a   Lindstrom, Jon ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 3 NICOTINIC RECEPTOR; ALPHA 4 NICOTINIC RECEPTOR; BETA 2 NICOTINIC RECEPTOR; BETA 4 NICOTINIC RECEPTOR; NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; VALINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CHIMERA; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFICACY; DRUG POTENCY; GENE MUTATION; HUMAN; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN STABILITY; SIGNAL TRANSDUCTION; XENOPUS LAEVIS;

ALKALOIDS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AZOCINES; ELECTROPHYSIOLOGY; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NICOTINE; PROTEIN SUBUNITS; QUINOLIZINES; RECEPTORS, NICOTINIC; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036266162     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.6.1416     Document Type: Article

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