Amiloride inhibition of γ-aminobutyric acidA receptors depends upon the α subunit subtype

Molecular Pharmacology

Volumn 61, Issue 6, 2002, Pages 1322-1328

  Fisher, Janet L ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AMILORIDE; DIURETIC AGENT; RECEPTOR SUBUNIT;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GABAERGIC SYSTEM; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; SENSORY NERVE CELL;

AMILORIDE; ANIMALS; CELLS, CULTURED; DIURETICS; FIBROBLASTS; FUROSEMIDE; GAMMA-AMINOBUTYRIC ACID; HUMANS; MICE; PENTOBARBITAL; PROTEIN SUBUNITS; RATS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0036259163     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.6.1322     Document Type: Article

References (34)

1. A receptor subunits: Analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique
2. A receptor subtypes differentiated by their γ-subunit variants: Prevalence, pharmacology and subunit architecture
3. + conductance
4. High-efficiency transformation of mammalian cells by plasmid DNA
5. Methyl isobutyl amiloride delays normalization of brain intracellular pH after cardiac arrest in rats
6. 2+ exchanger
7. 1 receptors in calf brain
8. A receptors in transfected L929 cells isolated by immunomagnetic bead separation
9. Gene knockout of the α6 subunit of the γ-aminobutyric acid type A receptor: Lack of effect on responses to ethanol, pentobarbital, and general anesthetics
10. Amiloride interacts with renal α- and β-adrenergic receptors
11. Effects of diuretics on GABA-gated chloride current in frog isolated sensory neurones
12. A receptor α6 subunit gene inactivation inhibits δ subunit expression
13. Toward a structural basis for the function of the nicotinic acetylcholine receptors and their cousins
14. Amiloride and its analogs as tools in the study of ion transport
15. A receptors α4β2γ2
16. A receptor
17. Selective antagonist for the cerebellar granule cell-specific γ-aminobutyric acid type A receptors
18. A receptor selective for a behavioural alcohol antagonist
19. A receptors
20. A receptor gene expression
21. + exchange
22. A receptor subunits in cerebellar granule cells after the disruption of the α6 subunit gene
23. A receptor α subunits after flurazepam treatment
24. A receptor subunits: Role of the 100 ∴ φ ∴ σ 12 subunit
25. A receptor isoforms
26. Contrasting actions of lanthanum on different recombinant γ-aminobutyric acid receptor isoforms expressed in L929 fibroblasts
27. A receptor subtypes
28. Local anti-angiogenic brain tumor therapies
29. A receptor subtype in the brain is not lethal in mice
30. A receptor subtype- selective antagonism by furosemide
31. A receptor: Dependence on receptor subunit combination
32. A receptor β subunit
33. A receptors containing the α4 subunit
34. Molecular and functional diversity of the expanding GABA-A receptor gene family