Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy

Carcinogenesis

Volumn 23, Issue 4, 2002, Pages 617-625

  Stiborová, Marie ^a   Frei, Eva ^b   Sopko, Bruno ^a   Wiessler, Manfred ^b   Schmeiser, Heinz H ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE OXIDASE; ARISTOLOCHIC ACID; ARISTOLOLACTAM; CHINESE DRUG; ENZYME INHIBITOR; NUCLEASE; OXIDOREDUCTASE; PHOSPHORUS 32; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CATALYSIS; CELL FRACTIONATION; CHINESE HERB; COMPUTER MODEL; COMPUTER PREDICTION; CONTROLLED STUDY; DNA ADDUCT; DRUG ACTIVATION; DRUG INDUCED DISEASE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME STRUCTURE; ISOTOPE LABELING; KIDNEY PARENCHYMA; LIVER CYTOSOL; MALE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RAT; UROGENITAL TRACT TUMOR; X RAY ANALYSIS;

EID: 0036257348     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/23.4.617     Document Type: Article

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