Pharmacological elevation of blood pressure in acute stroke: Clinical effects and safety

Stroke

Volumn 28, Issue 11, 1997, Pages 2133-2138

  Rordorf, Guy ^a   Cramer, Steven C ^a,b   Efird, James T ^a   Schwamm, Lee H ^a   Buonanno, Ferdinando ^a   Koroshetz, Walter J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

Hypertension; Phenylephrine; Stenosis; Stroke management

Indexed keywords

PHENYLEPHRINE;

ADULT; AGED; ARTICLE; BRAIN BLOOD FLOW; BRAIN PERFUSION; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STROKE; TREATMENT INDICATION;

EID: 0030698279     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.28.11.2133     Document Type: Article

References (59)

1. Britton M, Carlsson A. Very high blood pressure in acute stroke. J Intern Med. 1990;228:611-615.
2. Morfis L, Schwartz R, Lykos D, Zagami A, Pryor D, Howes LG. 24 Hour ambulatory blood pressure profiles in the acute phase of stroke. Clin Exp Pharmacol Physiol. 1995;22:775-777.
3. Prattichizzo FA, Galetta F, Bonechi I, Giusti C. Therapy of arterial hypertension associated with acute stroke: current trends and problems. Clin Ter. 1994;145:383-390.
4. Harper G, Fotherby, Panayiotou BJ, Castleden CM, Potter JF. The changes in blood pressure after acute stroke: abolishing the 'white coat effect' with 24-hr ambulatory monitoring. J Intern Med. 1994; 235:343-346.
5. Harper G, Castleden CM, Potter JF. Factors affecting changes in blood pressure after acute stroke. Stroke. 1994;25:1726-1729.
6. Wallace J, Levy L. Blood pressure after stroke. JAMA. 1981;246: 2177-2180.
7. Buonanno F, Toole J. Management of patients with established ('completed') cerebral infarction. Stroke. 1981;12:7-16.
8. Yatsu F, Zivin J. Hypertension in acute ischemic strokes: not to treat. Arch Neurol. 1985;42:999-1000.
9. Britton M, Faire UD, Helmers C. Hazards of therapy for excessive hypertension in acute stroke. Acta Med Scand. 1980;207:253-257.
10. Jorgensen HS, Nakayama H, Rasschou HO, Olsen TS. Effects of blood pressure and diabetes on stroke in progression. Lancet. 1994; 344;156-159.
11. Carlberg B, Asplund K, Hagg E. The prognostic value of admission blood pressure in patients with acute stroke. Stroke. 1993;24: 1372-1375.
12. Lisk DR, Grotta JC, Lamki LM, Tran HD, Taylor JW, Molony DA, Barron BJ. Should hypertension be treated after acute stroke? A randomized controlled trial using single photon emission computed tomography. Arch Neurol. 1993;50:855-862.
13. Adams HP, Brott TG, Crowell RM, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Marler JR, Woolson RF, Zivin JA, Feinberg W, Mayberg M. Guidelines for the management of patients with acute ischemic stroke: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Circulation. 1994;90:1588-1601.
14. Shanbrom E, Levy L. The role of systemic blood pressure in cerebral circulation in carotid and basilar artery thromboses. Cereb Circ. 1957:197-204.
15. Wise G. Vasopressor-drug therapy for complications of cerebral arteriography. N Engl J Med. 1970;282:610-612.
16. Wise G, Sutter R, Burkholder J. The treatment of brain ischemia with vasopressor drugs. Stroke. 1972;3:135-140.
17. Mayberg MR, Batjer HH, Dacey R, Diringer M, Haley EC, Heros RC, Sternau LL, Torner J, Adams HP, Feinberg W, Thies W. Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council. American Heart Association. Circulation. 1994;90:2592-2605.
18. Miller JA, Dacey RG Jr, Diringer MN. Safety of hypertensive hypervolemic therapy with phenylephrine in the treatment of delayed ischemic deficits after subarachnoid hemorrhage. Stroke. 1995;26:2260-2266.
19. Muizelaar J, Becker D. Induced hypertension for the treatment of cerebral ischemia after subarachnoid hemorrhage: direct effect on cerebral blood flow. Surg Neurol. 1986;25:317-325.
20. Rosenstein J, Suzuki M, Symon L, Redmond S. Clinical use of a portable bedside cerebral blood flow machine in the management of aneurysmal subarachnoid hemorrhage. Neurosurgery. 1984;15: 519-525.
21. Marchal G, Beaudouin V, Rioiux P, de la Sayette V, Le Doze F, Viader F, Derlon JM, Baron JC. Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: a correlative PET-CT study with voxel-based data analysis. Stroke. 1996;27:599-606.
22. Sorensen G, Buonanno F, Gonzalez G, Schwamm L, Lev M, Huang-Hellinger F, Reese T, Weisskoff R, Davis T, Suwanwela N, Can U, Moreira J, Copen W, Look R, Finkelstein S, Rosen B, Koroshetz W. Hyperacute stroke: evaluation with combined multisection diffusion-weighted and hemodynamically weighted echoplanar MR imaging. Radiology. 1996;199:391-401.
23. Knaus W, Draper E, Wagner D, Zimmerman J. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13: 818-829.
24. Mohr J, Caplan L, Melski J, Goldstein R, Duncan G, Kistler J, Pessin M, Bleich H. The Harvard Cooperative Stroke Registry: a prospective registry. Neurology. 1978;28:754-762.
25. Kassel N, Haley E, Durward Q, Beck D, Drake C, Adams H. Treatment of ischemic deficits from vasospasm with intravascular expansion and induced arterial hypertension. Neurosurgery. 1982; 11:337-343.
26. Kosnik E, Hunt W. Postoperative management of patients with intracranial arterial aneurysm. J Neurosurg. 1976;45:148-152.
27. Brown F, Hanlon K, Mullan S. Treatment of aneurysmal hemiplegia with dopamine and mannitol. J Neurosurg. 1978;49:525-529.
28. Pritz M, Giamotta S, Kindt G, McGillicuddy J, Prager R. Treatment of patients with neurological deficits associated with cerebral vasospasm by intravascular volume expansion. Neurosurgery. 1978;3:364-368.
29. Solomon R, Fink M, Lennihan L. Early aneurysm surgery and prophylactic hypervolemic hypertension therapy for the treatment of aneurysmal subarachnoid hemorrhage. Neurosurgery. 1988;23: 699-704.
30. Vonderak S, Pomerantz M. Reversal of ischemic neurological signs by increasing the cardiac output. Surg Neurol. 1973;1:257-258.
31. Farhat S, Schneider R. Observation on the effect of systemic blood pressure on intracranial circulation in patients with cerebrovascular insufficiency. J Neurosurg. 1967;27:441-445.
32. Wise G, Fontana M, Burkholder J, Leighton R, Sutter R, Molnar W. The treatment of brain ischemia following arteriography. Neuroradiology. 1974;110:383-390.
33. Meier F, Wessel G, Thiele R, Gottschild D, Brandstaett H. Induced hypertension as an approach to treating acute cerebrovascular ischemia: possibilities and limitations. Exp Pathol. 1991;42:257-264.
34. Aspey B, Ehteshami S, Hurst C, McCoy A, Harrison M. The effects of increased blood pressure on hemispheric lactate and water content during acute cerebral ischemia in rat and gerbil. J Neurol Neurosurg Psychiatry. 1987;50:1493-1498.
35. Drummond J, Oh Y, Cole D, Shapiro H. Phenylephrine-induced hypertension reduces ischemia following middle cerebral artery occlusion in rats. Stroke. 1989;20:1538-1544.
36. Cole D, Drummond J, Osborne T, Matsumura J. Hypertension and hemodilution during cerebral ischemia reduce brain injury and edema. Am J Physiol. 1990;259:H211-H217.
37. Hayashi S, Nehls D, Kieck C, Vielma J, DeGirolami U, Crowell R. Beneficial effects of induced hypertension on experimental stroke in awake monkeys. J Neurosurg. 1984;60:151-157.
38. Goldberg H, Banka R, Reivich M. Effect on regional cerebral blood flow in ischemic stroke of vasopressor therapy. Stroke. 1977;8:6. Abstract.
39. Hope D, Branston N, Symon L. Restoration of neurological function with induced hypertension in acute experimental cerebral ischemia. Acta Neurol Scand. 1977;56(suppl 64):506-507.
40. Waltz A. Effect of blood pressure on blood flow in ischemic and in nonischemic cerebral cortex: the phenomena of autoregulation and luxury perfusion. Neurology. 1968;18:613-621.
41. Smith HA, Thompson-Dobkin J, Yonas H, Flint E. Correlation of xenon-enhanced computed tomography-defined cerebral blood flow reactivity and collateral flow pattern. Stroke. 1994;25: 1784-1787.
42. Cole D, Matsumura J, Drummond J, Schell R. Focal cerebral ischemia in rats: effects of induced hypertension, during reperfusion, on CBF. J Cereb Blood Flow Metab. 1992;12:64-69.
43. Ackerman RH, Lev M, Mackay B, Katz P, Babikian V, Alpert N, Correia J, Panagos P, Senda M. PET studies in acute stroke: finding and relevance to therapy. J Cereb Blood Flow Metab. 1989;9(suppl 1):XX1-5.
44. Levy D, Uitert RV, Pike C. Delayed postischemic hypoperfusion: a potentially damaging consequence of stroke. Neurology. 1979;29: 1245-1252.
45. Shigeno T, Teasdale G, McCulloch J, Graham G. Recirculation model following MCA occlusion in rats: cerebral blood flow, cerebrovascular permeability, and brain edema. J Neurosurg. 1985;63: 272-277.
46. Miller C, Lampard D, Alexander K, Brown W. Local cerebral blood flow following transient cerebral ischemia. I: onset of impaired reperfusion within the first hour following global ischemia. Stroke. 1980;11:534-541.
47. Tegtmeier F, Weber C, Heister U, Haken I, Scheller D, Nikolov R, Hoeller M. Eicosanoids in rat brain during ischemia and reperfusion: correlation to DC depolarization. J Cereb Blood Flow Metab. 1990;10:358-364.
48. Obrenovitch T, Hallenbeck J. Platelet accumulation in regions of low blood flow during the postischemic period. Stroke. 1985;16: 224-234.
49. Vasthare U, Heinel L, Rosenwasser R, Tuma R. Leukocyte involvement in cerebral ischemia and reperfusion. Surg Neurol. 1990;33:261-265.
50. Ennis S, Keep R, Schielke G, Betz L. Decrease in perfusion of cerebral capillaries during incomplete ischemia and reperfusion. J Cereb Blood Flow Metab. 1990;10:213-220.
51. Little J, Kerr F, Sundt T. Microcirculatory obstruction in focal cerebral ischemia: an electron microscopic investigation in monkeys. Stroke. 1976;7:25-30.
52. Heiss W, Hayakawa T, Waltz A. Patterns of change of blood flow and relationships to infarction in experimental cerebral ischemia. Stroke. 1976;7:454-459.
53. Dutka A, Hallenbeck J, Kochanek P. A brief episode of severe arterial hypertension induces delayed deterioration of brain function and worsens blood flow after transient multifocal cerebral ischemia. Stroke. 1987;18:386-395.
54. Cole D, Drummond J, Marcantonio S, Matsumura J, Chi-Lum B. Hemodilution and hypertension during middle cerebral artery occlusion in rats: the effect on blood brain barrier permeability. Can J Neurol Sci. 1990;17:372-377.
55. Patel P, Drummond J, Cole D. Induced hypertension during restoration of flow after temporary middle cerebral artery occlusion in the rat: effect on neuronal injury and edema. Surg Neurol. 1991;36: 195-201.
56. Patel P, Drummond J, Cole D, Giamela R, Steinauer J. Delayed institution of hypertension during focal cerebral ischemia: effect on brain edema. Acta Neuropathol (Berl). 1991;81:339-344.
57. Olesen J. The effect of intracarotid epinephrine, norepinephrine, and angiotensin on the regional cerebral blood flow in man. Neurology. 1972;22:978-987.
58. Ferrari-DiLeo G, Potter L. Adrenoreceptors and muscarinic receptors in human pial arteries and microvessels: a receptor binding study. J Cereb Blood Flow Metab. 1985;5:458-464.
59. Starkey K, Docherty J. Alpha 1 and alpha 2 adrenoreceptors: pharmacology and clinical implications. J Cardiovasc Pharmacol. 1981;3(suppl 1):514-516.