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Volumn 37, Issue 5, 2002, Pages 391-398

(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden] (arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: Synthesis and biological properties

(11) Balsamo, Aldo a Coletta, Isabella c Domiano, Paolo b Guglielmotti, Angelo c Landolfi, Carla c Mancini, Francesca c Milanese, Claudio c Orlandini, Elisabetta a Rapposelli, Simona a Pinza, Mario c Macchia, Bruno a

a UNIVERSITY OF PISA (Italy)

b UNIVERSITY OF PARMA (Italy)

c Università Politecnica delle Marche ACRAF Gruppo Angelini (Italy)

Author keywords

(E) 2 (4 methylsulphonylphenyl) 1 cyclopentenyl 1 methylidene (arylmethyloxy)amines; Antiinflammatory drug; COX 2 inhibitor; Methyleneaminoxymethyl moiety

Indexed keywords

1 (4 FLUOROPHENYL) 2 [(4 METHYLSULFONYL)PHENYL]CYCLOPENTENE; 5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; AMINE; CARRAGEENAN; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ENZYME INHIBITOR; INDOMETACIN; METHYL GROUP; METHYLENEAMINOXYMETHYL; PROSTAGLANDIN E2; ROFECOXIB; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL LINE; CELL STRAIN U937; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; MACROPHAGE; NONHUMAN; PAW EDEMA; PROSTAGLANDIN SYNTHESIS; RAT; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; CELL LINE; CRYSTALLOGRAPHY, X-RAY; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; CYCLOPENTANES; EDEMA; HETEROCYCLIC COMPOUNDS, 2-RING; ISOENZYMES; MACROPHAGES; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; SULFHYDRYL COMPOUNDS;

EID: 0036238510 PISSN: 02235234 EISSN: None Source Type: Journal
DOI: 10.1016/S0223-5234(02)01359-4 Document Type: Article

Times cited : (14)

References (34)

1
- 0015237292
- (1971) Nature , vol.231 , pp. 232-235
- Vane, J.R.¹

2
- 0004043489
- New York: Wiley; Wiley Interscience
- (1985) Nonsteroidal Antiinflammatory Drugs
- Lombardino, G.¹

3
- 0030461132
- (1996) Nature , vol.384 , pp. 644-648
- Kurumbail, R.G.¹ Stevens, A.M.² Gierse, J.K.³ McDonald, J.J.⁴ Stegerman, R.A.⁵ Pak, J.Y.⁶ Gildehaus, D.⁷ Miyashiro, J.M.⁸ Penning, T.D.⁹ Seibert, K.¹⁰ Isakson, P.C.¹¹ Stallings, W.C.¹²

4
- 0032788120
- (1999) Drugs Today , vol.35 , pp. 237-250
- Bakhle, Y.S.¹

5
- 0025871150
- (1991) J. Biol. Chem. , vol.266 , pp. 12866-12872
- Kujubu, D.A.¹ Fletcher, B.S.² Varnum, B.C.³ Lim, R.W.⁴ Herschman, H.R.⁵

6
- 0027076645
- (1992) J. Biol. Chem. , vol.267 , pp. 25934-25938
- Lee, S.H.¹ Soyoola, E.² Chanmugam, P.³ Hart, S.⁴ Sun, W.⁵ Zhong, H.⁶ Liou, S.⁷ Simmons, D.⁸ Hwang, D.⁹

7
- 0027306036
- (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 1294-1300
- O'Sullivan, M.G.¹ Huggins E.M., Jr.² McCall, C.E.³

8
- 0026788165
- (1992) New Engl. J. Med. , vol.327 , pp. 749-754
- Allison, M.C.¹ Howatson, A.G.² Torrance, C.J.³ Lee, F.D.⁴ Russell, R.I.G.⁵

9
- 0028889567
- (1995) J. Med. Chem. , vol.38 , pp. 4570-4578
- Li, J.J.¹ Anderson, G.D.² Burton, E.G.³ Cogburn, J.N.⁴ Collins, J.T.⁵ Garland, D.J.⁶ Gregory, S.A.⁷ Huang, H.-C.⁸ Isakson, P.C.⁹ Koboldt, C.M.¹⁰ Logusch, E.W.¹¹ Norton, M.B.¹² Perkins, W.E.¹³ Reinhard, E.J.¹⁴ Seibert, K.¹⁵ Veenhuizen, A.W.¹⁶ Zhang, Y.¹⁷ Reitz, D.B.¹⁸

10
- 0030029368
- (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 87-92
- Gauthier, J.Y.¹ Leblanc, Y.² Black, W.C.³ Chan, C.C.⁴ Cromlish, W.A.⁵ Gordon, R.⁶ Kennedy, B.P.⁷ Lau, C.K.⁸ Leger, S.⁹ Wang, Z.¹⁰ Ethier, D.¹¹ Guay, J.¹² Mancini, J.¹³ Riendeau, D.¹⁴ Tagari, P.¹⁵ Vickers, P.¹⁶ Wong, E.¹⁷ Xu, L.¹⁸ Prasit, P.¹⁹

11
- 0029981646
- (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 725-730
- Black, W.C.¹ Bayly, C.² Belley, M.³ Chan, C.C.⁴ Charleson, S.⁵ Denis, D.⁶ Gauthier, J.Y.⁷ Gordon, R.⁸ Guay, D.⁹ Kargman, S.¹⁰ Leblanc, Y.¹¹ Mancini, J.¹² Ouellet, M.¹³ Percival, D.¹⁴ Roy, P.¹⁵ Skorey, K.¹⁶ Tagari, P.¹⁷ Vickers, P.¹⁸ Wong, E.¹⁹ Xu, L.²⁰ Prasit, P.²¹ more..

12
- 0025160887
- (1990) J. Pharmacol. Exp. Ther. , vol.254 , pp. 180-187
- Gans, K.R.¹ Galbraith, W.² Roman, R.J.³ Haber, S.B.⁴ Kerr, J.S.⁵ Schmidt, W.K.⁶ Smith, C.⁷ Hewes, W.E.⁸ Ackerman, N.R.⁹

15
- 0027944191
- (1994) J. Med. Chem. , vol.37 , pp. 3878-3881
- Reitz, D.B.¹ Li, J.J.² Norton, M.B.³ Reinhard, E.J.⁴ Collins, J.T.⁵ Anderson, G.D.⁶ Gregory, S.A.⁷ Koboldt, C.M.⁸ Perkins, W.E.⁹ Seibert, K.¹⁰ Isakson, P.C.¹¹

16
- 0000647033
- (1995) Med. Chem. Res. , vol.5 , pp. 399-408
- Wilkerson, W.W.¹ Copeland, R.A.² Covington, M.B.³ Grubb, M.F.⁴ Hewes, W.E.⁵ Kerr, J.S.⁶ Trzaskos, J.M.⁷

17
- 0034624748
- (2000) J. Med. Chem. , vol.43 , pp. 775-777
- Talley, J.J.¹ Brown, D.L.² Carter, J.S.³ Graneto, M.J.⁴ Koboldt, C.M.⁵ Masferrer, J.L.⁶ Perkins, W.E.⁷ Rogers, R.S.⁸ Shaffer, A.F.⁹ Zhang, Y.Y.¹⁰ Zweifel, B.S.¹¹ Seibert, K.¹²

18
- 0021965957
- (1985) J. Med. Chem. , vol.28 , pp. 153-160
- Macchia, B.¹ Balsamo, A.² Lapucci, A.³ Martinelli, A.⁴ Macchia, F.⁵ Breschi, M.C.⁶ Fantoni, B.⁷ Martinotti, E.⁸

19
- 0023251051
- (1987) J. Med. Chem. , vol.30 , pp. 616-622
- Macchia, B.¹ Balsamo, A.² Lapucci, A.³ Macchia, F.⁴ Martinelli, A.⁵ Ammon, H.L.⁶ Prasad, S.M.⁷ Breschi, M.C.⁸ Ducci, M.⁹ Martinotti, E.¹⁰

20
- 0028334669
- (1994) J. Med. Chem. , vol.37 , pp. 1518-1525
- Macchia, B.¹ Balsamo, A.² Breschi, M.C.³ Chiellini, G.⁴ Macchia, M.⁵ Martinelli, A.⁶ Martini, C.⁷ Nardini, C.⁸ Nencetti, S.⁹ Rossello, A.¹⁰ Scatizzi, R.¹¹

21
- 0025305393
- (1990) J. Med. Chem. , vol.33 , pp. 1423-1430
- Macchia, B.¹ Balsamo, A.² Lapucci, A.³ Macchia, F.⁴ Martinelli, A.⁵ Nencetti, S.⁶ Orlandini, E.⁷ Baldacci, M.⁸ Mengozzi, G.⁹ Soldani, G.¹⁰ Domiano, P.¹¹

22
- 0028575913
- (1994) Eur. J. Med. Chem. , vol.29 , pp. 967-973
- Balsamo, A.¹ Lapucci, A.² Lucacchini, A.³ Macchia, M.⁴ Martini, C.⁵ Nardini, C.⁶ Nencetti, S.⁷

23
- 0024337837
- (1989) J. Med. Chem. , vol.32 , pp. 1398-1401
- Balsamo, A.¹ Broccali, G.² Lapucci, A.³ Macchia, B.⁴ Macchia, F.⁵ Orlandini, E.⁶ Rossello, A.⁷

24
- 0032752444
- (1999) Eur. J. Med. Chem. , vol.34 , pp. 283-291
- Balsamo, A.¹ Macchia, M.² Martinelli, A.³ Rossello, A.⁴

25
- 0029899186
- (1996) J. Biol. Chem. , vol.271 , pp. 15810-15814
- Gierse, J.K.¹ McDonald, J.J.² Hauser, S.D.³ Rangwala, S.H.⁴ Koboldt, C.M.⁵ Seibert, K.⁶

26
- 0001082561
- (1988) Tetrahedron Lett. , vol.29 , pp. 5789-5792
- Rajamannar, T.¹ Balasubramanian, K.K.²

27
- 2042507954
- (1995) Chem. Rev. , vol.95 , pp. 2457-2483
- Miyaura, N.¹ Suzuki, A.²

29
- 0028088686
- (1994) Eur. J. Med. Chem. , vol.29 , pp. 787-794
- Balsamo, A.¹ Belfiore, M.S.² Macchia, M.³ Martini, C.⁴ Nencetti, S.⁵ Orlandini, E.⁶ Rossello, A.⁷

30
- 0242560405
- (1999) J. Appl. Crystallogr. , vol.32 , pp. 115-119
- Altomare, A.¹ Burla, M.C.² Camalli, M.³ Cascarano, G.⁴ Giacovazzo, C.⁵ Guagliardi, A.⁶ Moliterni, A.G.G.⁷ Polidori, G.⁸ Spagna, R.⁹

31
- 0008951905
- University of Göttingen, Germany
- (1996)
- Sheldrick, G.M.¹

32
- 0027146692
- (1994) Prot. Natl. Acad. Sci. USA , vol.90 , pp. 11693-11697
- Mitchell, J.A.¹ Akarasereenont, P.² Thiemermann, C.³ Flower, R.J.⁴ Vane, J.R.⁵

33
- 0029029296
- (1995) Inflamm. Res. , vol.44 , pp. 253-257
- Grossman, C.J.¹ Wiseman, J.² Lucas, F.S.³ Trevethick, M.A.⁴ Birch, P.J.⁵

34
- 67249094291
- (1962) Proc. Soc. Exp. Biol. Med. , vol.111 , pp. 544-547
- Winter, C.A.¹ Risley, E.A.² Nuss, G.W.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.