Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters

Clinical Pharmacology and Therapeutics

Volumn 71, Issue 3, 2002, Pages 131-140

  Glaeser, Hartmut ^a,b,c,d   Drescher, Siegfried ^a,b,c,d   Van Der Kuip, Heiko ^e   Behrens, Christoph ^e   Geick, Anke ^e   Burk, Oliver ^e   Dent, John ^e   Somogyi, Andrew ^e   Von Richter, Oliver ^e   Griese, Ernst Ulrich ^e   Eichelbaum, Michel ^e   Fromm, Martin F ^e  

^a DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^b ROYAL ADELAIDE HOSPITAL   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CARRIER PROTEIN; CD45 ANTIGEN; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; CYTOCHROME P450 ISOENZYME; DRUG METABOLIZING ENZYME; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOPROTEIN P; MESSENGER RNA; UNCLASSIFIED DRUG; VERAPAMIL; VERAPAMIL DERIVATIVE; VILLIN;

ADULT; APOPTOSIS; ARTICLE; CELL DEATH; CELL FREE SYSTEM; CELL FUNCTION; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; INTESTINE CELL; JEJUNUM; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADULT; CALCIUM CHANNEL BLOCKERS; CARRIER PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; ENTEROCYTES; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GENOTYPE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JEJUNUM; MALE; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; PHOSPHOPROTEINS; POLYMORPHISM, GENETIC; VERAPAMIL;

EID: 0036215323     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2002.121370     Document Type: Article

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