Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique

Clinical Pharmacology and Therapeutics

Volumn 70, Issue 3, 2001, Pages 217-227

  Von Richter, Oliver ^{a,b,c,d,e,f,g}   Greiner, Bernd ^{a,b,c,d,e,f,g}   Fromm, Martin F ^{a,b,c,d,e,f,g}   Fraser, Robert ^{a,b,c,d,e,f,g}   Omari, Taher ^{a,b,c,d,e,f,g}   Barclay, Murray L ^{a,b,c,d,e,f,g}   Dent, John ^{a,b,c,d,e,f,g}   Somogyi, Andrew A ^{a,b,c,d,e,f,g}   Eichelbaum, Michel ^{a,b,c,d,e,f,g,h}  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b MERCK KGAA   (Germany)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d ROYAL ADELAIDE HOSPITAL   (Australia)

^e Dentsleeve Pty Ltd   (Australia)

^f WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^g Christchurch Hospital   (Germany)

^h DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; VERAPAMIL;

ADULT; ARTICLE; BILIARY EXCRETION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG ELIMINATION; DRUG METABOLISM; DRUG TRANSPORT; FIRST PASS EFFECT; HUMAN; HUMAN EXPERIMENT; INTESTINE CELL; INTESTINE SECRETION; INTESTINE WALL; LIVER; MALE; NORMAL HUMAN; PERFUSION; PRIORITY JOURNAL;

ADULT; ALGORITHMS; AREA UNDER CURVE; BILE; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CALCIUM CHANNEL BLOCKERS; HUMANS; INTESTINAL ABSORPTION; INTESTINES; LIVER; MALE; MIDDLE AGED; PERFUSION; PHARMACEUTICAL PREPARATIONS; VERAPAMIL;

EID: 0034827018     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2001.117937     Document Type: Article

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