Positive selection scanning reveals decoupling of enzymatic activities of carbamoyl phosphate synthetase in Helicobacter pylori

Journal of Molecular Evolution

Volumn 54, Issue 4, 2002, Pages 458-464

  Davids, Wagied ^a   Gamieldien, Junaid ^b   Liberles, David A ^a   Hide, Winston ^b  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

Adaptation; Bioinformatics; Human pathogen; Molecular evolution; Pathoadaptive mutations; Structure function correlation

Indexed keywords

ARGININE; CARBAMOYL PHOSPHATE SYNTHASE; PYRIMIDINE;

ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ISOLATION; GENETIC SELECTION; HELICOBACTER PYLORI; NONHUMAN; NUCLEOTIDE METABOLISM; PRESSURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CARBON-NITROGEN LIGASES WITH GLUTAMINE AS AMIDE-N-DONOR; EVOLUTION, MOLECULAR; HELICOBACTER PYLORI; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HELICOBACTER; HELICOBACTER PYLORI;

EID: 0036213742     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-001-0029-6     Document Type: Article

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