Is p53 haploinsufficient for tumor suppression? Implications for the p53+/- mouse model in carcinogenicity testing

Toxicologic Pathology

Volumn 29, Issue 5 SUPPL., 2001, Pages 147-154

  Donehower, Lawrence A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Carcinogenicity testing; Genotoxic carcinogens; Knockout mice; Loss of heterozygosity; Mouse cancer model; Tumor suppressor

Indexed keywords

EID: 0034750997     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. +/- mouse. Toxicol Pathol 27: 519-527.
2. +/- mice: Evidence of chromosomal recombination. Cancer Res 60: 2831-2835.