The chemokine repertoire of human dermal microvascular endothelial cells and its regulation by inflammatory cytokines

Journal of Investigative Dermatology

Volumn 108, Issue 4, 1997, Pages 445-451

  Goebeler, Matthias ^a   Yoshimura, Teizo ^b   Toksoy, Atiye ^a   Ritter, Uwe ^a   Bröcker, Eva Bettina ^a   Gillitzer, Reinhard ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

GRO; interleukin 8; monocyte chemoattractant protein 1; RANTES

Indexed keywords

CHEMOKINE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 8; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SKIN INFLAMMATION; VASCULAR ENDOTHELIUM;

EID: 0030929693     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12289711     Document Type: Article

References (47)

1. Ades EW, Candal FJ, Swerlick RA, George VG, Summers S, Bosse DC, Lawley TJ: HMEC-1: establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol 99:683-690, 1992
2. Anisowicz A, Bardwell L, Sager R: Constitutive overexpression of a growth-related gene in transformed Chinese hamster ovary cells. Proc Natl Acad Sci USA 84:7188-7192, 1987
3. Baggiolini M, Dewald B, Moser B: Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol 55:97-179, 1994
4. Barker JNWN, Jones ML, Swenson CL, Sarma V, Mitra RS, Ward PA, Johnson KJ, Fantone JC, Dixit VM, Nickoloff BJ: Monocyte chemotaxis and activating factor production by keratinocytes in response to 1FN-γ. J Immunol 146:1192-1197, 1991
5. Boorsma DM, de Haan P, Willemze R, Stoof TJ: Human growth factor (huGRO), interleukin-8 (IL-8) and interferon-γ-inducible protein (γ-IP-10) gene expression in cultured normal human keratinocytes. Arch Dermatol Res 286:471-475, 1994
6. Brown Z, Gerritsen ME, Carley WW, Strieter RM, Kunkel SL, Westwick J: Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Differential regulation of monocyte chemoattractant protein-1 and interleukin-8 in response to interferon-gamma. Am J Pathol 145:913-921, 1994
7. Callard RE, Matthews DJ, Hibbert L: IL-4 and IL-13 receptors: are they one and the same? Immunol Today 17:108-110, 1996
8. Carr MW, Alon R, Springer TA: The C-C chemokine MCP-1 differentially modulates the avidity of β1 and β2 integrins on T lymphocytes. Immunity 4:179-187, 1996
9. Farber JM: HuMIG: a new memher of the chemokine family of cytokines. Biochem Biophys Res Commun 192:223-230, 1993
10. Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD: Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 2:449-456, 1996
11. Gillitzer R, Berger R, Mielke V, Müller W, Wolff K, Stingl G: Upper keratinocytes of psoriatic skin lesions express high levels of NAP-1/IL-8 mRNA in situ. J Invest Dermatol 97:73-79, 1991
12. Gillitzer R, Wolff K, Tong D, Müller C, Yoshimura T, Hartmann AA, Stingl G, Berger R: MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions. J Invest Dermatol 101:127-131, 1993
13. Gimbrone MA, Jr., Obin MS, Brock AF, Luis EA, Hass PE, Hebert CA, Yip YK, Leung DW, Lowe DG, Kohr WJ, Dabronne W, Bechtal KB, Baker JB: Endothelial interleukin-8: a novel inhibitor of leukocyte-endothelial interactions. Science 246:1601-1603, 1989
14. Goebeler M, Roth J, Bröcker EB, Sorg C, Schulze Osthoff K: Activation of nuclear factor-kappa B and gene expression in human endothelial cells by the common haptens nickel and cobalt. J Immunol 155:2459-2467, 1995
15. Gröger M, Sarmay G, Fiebiger E, Wolff K, Petzelbauer P: Dermal microvascular endothelial cells express CD32 receptors in vivo and in vitro. J Immunol 156:1549-1556, 1996
16. Haskill S, Peace A, Morris J, Sporn SA, Anisowicz A, Lee SW, Smith T, Martin G, Ralph P, Sager R: Identification of three related human GRO genes encoding cytokine functions. Proc Natl Acad Sci USA 87:7732-7736, 1990
17. Huber AR, Kunkel SL, Todd III RF, Weiss SJ: Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 254:99-102, 1991
18. Kuratsu J, Yoshizato K, Yoshimura T, Leonard EJ, Takeshima H, Ushio Y: Quantitative study of monocyte chemoattractant protein-1 (MCP-1) in cerebrospinal fluid and cyst fluid from patients with malignant glioma. J Natl Cancer Inst 85:1836-1839, 1993
19. Li J, Ireland GW, Farthing PM, Thornhill MH: Epidermal and oral keratinocytes are induced to produce RANTES and IL-8 by cytokine stimulation, J Invest Dermatol 106:661-666, 1996
20. Lloyd AR, Oppenheim JJ, Kelvin DJ, Taub DD: Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins. J Immunol 156:932-938, 1996
21. Luster AD, Ravetch JV: Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J Exp Med 166:1084-1097, 1987
22. Mantovani A, Bussolino F, Dejana E: Cytokine regulation of endothelial cell function. FASEB J 6:2591-2599, 1992
23. Marfaing Koka A, Devergne O, Gorgone G, Portier A, Schall TJ, Galanaud P, Emilie D: Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13. J Immunol 154:1870-1878, 1995
24. Noso N, Sticherling M, Bartels J, Mallet AI, Christophers E, Schröder J-M: Identification of an N-terminally truncated form of the chemokine RANTES and granulocyte-macrophage colony-stimulating factor as major eosinophil attractants released by cytokine-stimulated fibroblasts. J Immunol 156:1946-1953, 1996
25. Osborn L: Leukocyte adhesion to endothelium in inflammation. Cell 62:3-6, 1990
26. Petzelbauer P, Bender JR, Wilson J, Pober JS: Heterogeneity of dermal microvascular endothelial cell antigen expression and cytokine responsiveness in situ and in cell culture. J Immunol 151:5062-5072, 1993
27. Ponath PD, Quin S, Ringler DJ, Clark-Lewis I, Wang J, Kassam N, Smith H, Shi X, Gonzalo J-A, Newman W, Gutierrez-Ramos J-C, Mackay CR: Cloning of human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J Clin Invest 97:604-612, 1996
28. Randolph GJ, Furie MB: A soluble gradient of endogenous monocyte chemoattractant protein-1 promotes the transendothelial migration of monocytes In vitro. J Immunol 155:3610-3618, 1995
29. Ritter U, Moll H, Laskay T, Bröcker EB, Velazco O, Becker I, Gillitzer R: Differential expression of chemokines in patients with localized and diffuse American leishmaniasis. J Infect Dis 173:699-709, 1996
30. Rollins BJ, Pober JS: Interleukin-4 induces synthesis and secretion of MCP-1/JE by human endothelial cells. Am J Pathol 138:1315-1319, 1991
31. Rollins BJ, Yoshimura T, Leonard EJ, Pober JS: Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE. Am J Pathol 136:1229-1233, 1990
32. Rot A, Hub E, Middleton J, Pons F, Rabeck C, Thierer K, Wintle J, Wolff B, Zsak M, Dukor P: Some aspects of IL-8 pathophysiology III: chemokine interaction with endothelial cells. J Leukocyte Biol 59:39-44, 1996
33. Ruszczak Z, Detmar M, Imcke E, Orfanos CE: Effects of rIFN alpha, beta and gamma on the morphology, proliferation, and cell surface antigen expression of human dermal microvascular endothelial cells in vitro. J Invest Dermatol 95:693-699, 1990
34. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989
35. Schröder JM, Christophers E: Secretion of novel and homologous neutrophil-activating peptides by LPS-stimulated human endothelial cells. J Immunol 142: 244-251, 1989
36. Schröder J-M, Christophers E: Identification of C5a desarg and an anionic neutrophil-activating peptide (ANAP) in psoriatic scales. J Invest Dermatol 87:53-58, 1986
37. 3 integrin complex on human microvascular endothelial cells. J Invest Dermatol 103:295-299, 1994
38. Springer TA: Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301-314, 1994
39. Sticherling M, Hetzel F, Schröder J-M, Christophers E: Time- and stimulus-dependent secretion of NAP-1/IL-8 by human fibroblasts and endothelial cells. J Invest Dermatol 101:573-576, 1993
40. Swerlick RA, Garcia-Gonzalez E, Kubota Y, Xu Y, Lawley TJ: Human dermal microvascular endothelial but not human umbilical vein endothelial cells express CD36 in vivo and in vitro. J Immunol 148:78-83, 1992a
41. Swerlick RA, Lawley TJ: Role of microvascular endothelial cells in inflammation. J Invest Dermatol 100:111S-115S, 1993
42. Swerlick RA, Lee KH, Li LJ, Sepp NT, Caughman SW, Lawley TJ: Regulation of vascular cell adhesion molecule 1 on human dermal microvascular endothelial cells. J Immunol 149:698-705, 1992b
43. Tanaka Y, Adams DH, Hubscher S, Hirano H, Siebenlist U, Shaw S: T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature 361:79-82, 1993
44. Wen D, Rowland A, Derynck R: Expression and secretion of gro/MGSA by stimulated human endothelial cells. EMBO J 8:1761-1766, 1989
45. Xu Y, Swerlick RA, Sepp N, Bosse N, Ades AW, Lawley TJ: Characterization of expression and modulation of cell adhesion molecules on an immortalized human dermal microvascular endothelial cell line (HMEC-1). J Invest Dermatol 102:833-837, 1994
46. Yoshimura T, Takeya M, Takahashi K, Kuratsu J, Leonard EJ: Production and characterization of mouse monoclonal antibodies against human monocyte chemoattractant protein-1. J Immunol 147:2229-2233, 1991
47. Yoshimura T, Yuhki N, Moore SK, Apella E, Lerman MI, Leonard EJ: Human monocyte chemoattractant protein-1 (MCP-1): Full length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE. FEBS Lett 244:487-493, 1989