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Volumn 56, Issue 3, 1996, Pages 616-622

Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE;

EID: 0030023142     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (29)

References (56)
  • 1
    • 0026317881 scopus 로고
    • High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer
    • El-Detry, W. S., Nelkin, B. D., Celano, P , Yen, R-W. C., Falco, J P., Hamilton, S. R., and Baylin, S. B. High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer. Proc. Natl. Acad. Sci. USA, 88: 3470-3474, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3470-3474
    • El-Detry, W.S.1    Nelkin, B.D.2    Celano, P.3    Yen, R.-W.C.4    Falco, J.P.5    Hamilton, S.R.6    Baylin, S.B.7
  • 3
    • 0026076727 scopus 로고
    • Abnormal patterns of DNA methylation in human neoplasia: Potential consequences for tumor progression
    • Baylin, S B , Makos, M., Wu, J., Yen, R-W. C., de Bustros, A , Vertino, P., and Nelkin, B. D. Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression. Cancer Cells, 3: 383-390, 1991.
    • (1991) Cancer Cells , vol.3 , pp. 383-390
    • Baylin, S.B.1    Makos, M.2    Wu, J.3    Yen, R.-W.C.4    De Bustros, A.5    Vertino, P.6    Nelkin, B.D.7
  • 4
    • 0028074299 scopus 로고
    • DNA methylation and cancer
    • Laird, P. W., and Jaenisch, R. DNA methylation and cancer. Hum Mol. Genet., 3: 1487-1495, 1994.
    • (1994) Hum Mol. Genet. , vol.3 , pp. 1487-1495
    • Laird, P.W.1    Jaenisch, R.2
  • 5
    • 0027504621 scopus 로고
    • Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
    • Wu, J., Issa, J-P., Herman, J., Bassett, D E Jr., Nelkin, B. D., and Baylin, S. B. Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells. Proc. Natl. Acad. Sci. USA. 90: 8891-8895, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8891-8895
    • Wu, J.1    Issa, J.-P.2    Herman, J.3    Bassett Jr., D.E.4    Nelkin, B.D.5    Baylin, S.B.6
  • 7
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • Cedar, H. DNA methylation and gene activity. Cell, 53: 3-4, 1988.
    • (1988) Cell , vol.53 , pp. 3-4
    • Cedar, H.1
  • 8
    • 0025266610 scopus 로고
    • Alternative chromatin structure at CpG islands
    • Tazi, J., and Bird, A. Alternative chromatin structure at CpG islands. Cell. 60: 909-920, 1990.
    • (1990) Cell , vol.60 , pp. 909-920
    • Tazi, J.1    Bird, A.2
  • 9
    • 0025975985 scopus 로고
    • DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
    • Boyes, J., and Bird, A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein Cell, 64: 1123-1134, 1991.
    • (1991) Cell , vol.64 , pp. 1123-1134
    • Boyes, J.1    Bird, A.2
  • 10
    • 0022545498 scopus 로고
    • DNA methylation affects the formation of active chromatin
    • Keshet, I., Lieman-Hurwitz, J., and Cedar, H. DNA methylation affects the formation of active chromatin. Cell, 44: 535-543, 1986.
    • (1986) Cell , vol.44 , pp. 535-543
    • Keshet, I.1    Lieman-Hurwitz, J.2    Cedar, H.3
  • 12
    • 0025006860 scopus 로고
    • High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
    • Antequera, F., Boyes, J., and Bird, A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell, 62: 503-514, 1990.
    • (1990) Cell , vol.62 , pp. 503-514
    • Antequera, F.1    Boyes, J.2    Bird, A.3
  • 14
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita, N., Fujita, T., Aoike, A., Osifchin, N. E., Robbins, P. D., and Sakai, T. CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene, 8: 1063-1067, 1993.
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 16
    • 0029011539 scopus 로고
    • 5′CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Burger, P. C. Baylin, S. B., and Sidransky, D. 5′CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med., 1, 686-692, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Burger, P.C.5    Baylin, S.B.6    Sidransky, D.7
  • 17
    • 0027093283 scopus 로고
    • High frequency mutagenesis by a DNA methyltransferase
    • Shen, J-C., Rideout, W M , III, and Jones, P. A. High frequency mutagenesis by a DNA methyltransferase. Cell, 71: 1073-1080, 1992.
    • (1992) Cell , vol.71 , pp. 1073-1080
    • Shen, J.-C.1    Rideout III, W.M.2    Jones, P.A.3
  • 18
    • 0026697174 scopus 로고
    • Activation of mammalian DNA methyltransferase by cleavage of a zinc-binding regulatory domain
    • Bestor, T. Activation of mammalian DNA methyltransferase by cleavage of a zinc-binding regulatory domain. EMBO J., 11: 2611-2617, 1992.
    • (1992) EMBO J. , vol.11 , pp. 2611-2617
    • Bestor, T.1
  • 19
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. the carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor, T , Laudano, A., Mattaliano, R., and Ingram, V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J. Mol Biol., 203: 971-983, 1988.
    • (1988) J. Mol Biol. , vol.203 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 20
    • 0024604147 scopus 로고
    • Predictive motifs derived from cytosine methyltransferases
    • Posfai, J., Bhagwat, A S , Posfai, G., and Roberts, R. J. Predictive motifs derived from cytosine methyltransferases. Nucleic Acids Res., 17: 2421-2435, 1989.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 2421-2435
    • Posfai, J.1    Bhagwat, A.S.2    Posfai, G.3    Roberts, R.J.4
  • 22
    • 0023273532 scopus 로고
    • Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase
    • Caserta, M., Zacharias, W , Nwankwo, D., Wilson, G. G., and Wells, R. D. Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase. J. Biol. Chem., 262: 4770-4777, 1987
    • (1987) J. Biol. Chem. , vol.262 , pp. 4770-4777
    • Caserta, M.1    Zacharias, W.2    Nwankwo, D.3    Wilson, G.G.4    Wells, R.D.5
  • 23
    • 0021674863 scopus 로고
    • Construction and applications of a highly transmissible murine retrovirus shuttle vector
    • Cepko, C. L., Roberts, B., and Mulligan, R. C. Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell, 37: 1053-1062, 1984.
    • (1984) Cell , vol.37 , pp. 1053-1062
    • Cepko, C.L.1    Roberts, B.2    Mulligan, R.C.3
  • 24
    • 0025318790 scopus 로고
    • A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells
    • Morgenstern, J. P., and Land, H. A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells. Nucleic Acids Res., 18: 1068, 1990.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1068
    • Morgenstern, J.P.1    Land, H.2
  • 25
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Washington DC
    • Baker, S J., Markowitz, S , Fearon, E. R., Wilson, J. K. V , and Vogelstein, B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science (Washington DC), 249: 912-915, 1990.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3    Wilson, J.K.V.4    Vogelstein, B.5
  • 26
    • 0024529886 scopus 로고
    • Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene
    • Karasuyama, H , Tohyama, N., and Tada, T. Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene J Exp. Med., 169: 13-25, 1989.
    • (1989) J Exp. Med. , vol.169 , pp. 13-25
    • Karasuyama, H.1    Tohyama, N.2    Tada, T.3
  • 27
    • 0023877744 scopus 로고
    • Differential expression of four linked sheep metallothionein genes
    • Peterson, M. G., and Mercer, J F Differential expression of four linked sheep metallothionein genes Eur J. Biochem., 174: 425-429, 1988.
    • (1988) Eur J. Biochem. , vol.174 , pp. 425-429
    • Peterson, M.G.1    Mercer, J.F.2
  • 28
    • 0025896042 scopus 로고
    • Inducible transformation of fibroblasts using a metallothionein-v-myc gene construct
    • Bonham, L , Kwok, J., Chisholm, O , and Symonds, G. Inducible transformation of fibroblasts using a metallothionein-v-myc gene construct. Oncogene, 6: 1073-1077, 1991.
    • (1991) Oncogene , vol.6 , pp. 1073-1077
    • Bonham, L.1    Kwok, J.2    Chisholm, O.3    Symonds, G.4
  • 29
    • 85016731055 scopus 로고
    • Using PCR to engineer DNA
    • H. A. Erlich (ed.), New York: Stockton Press
    • Higachi, R Using PCR to engineer DNA. In: H. A. Erlich (ed.), PCR Technology, pp. 61-70. New York: Stockton Press, 1994.
    • (1994) PCR Technology , pp. 61-70
    • Higachi, R.1
  • 31
    • 0026585662 scopus 로고
    • Substitutions of a cysteine conserved among DNA cytosine methylases result in a variety of phenotypes
    • Wyszynski, M. W., Gabbara, S., and Bhagwat, A. S. Substitutions of a cysteine conserved among DNA cytosine methylases result in a variety of phenotypes Nucleic Acids Res., 20. 319-326, 1992
    • (1992) Nucleic Acids Res. , vol.20 , pp. 319-326
    • Wyszynski, M.W.1    Gabbara, S.2    Bhagwat, A.S.3
  • 32
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham, F. L., and van der Eb, A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology, 52: 456-467, 1973.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 33
    • 0019801414 scopus 로고
    • Enhancing the efficiency of DNA-mediated gene transfer in mammalian cells
    • Corsaro, C. M., and Pearson, M. L. Enhancing the efficiency of DNA-mediated gene transfer in mammalian cells. Somat. Cell Genet., 7: 603-616, 1981.
    • (1981) Somat. Cell Genet. , vol.7 , pp. 603-616
    • Corsaro, C.M.1    Pearson, M.L.2
  • 35
    • 0021086610 scopus 로고
    • Two DNA methyltransferases from murine erythroleukemia cells, purification, sequence specificty, and mode of interaction with DNA
    • Bestor, T. H , and Ingram, V. H Two DNA methyltransferases from murine erythroleukemia cells, purification, sequence specificty, and mode of interaction with DNA. Proc. Natl. Acad. Sci. USA, 80: 5559-5563, 1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 5559-5563
    • Bestor, T.H.1    Ingram, V.H.2
  • 36
    • 0026629881 scopus 로고
    • Vector methylation inhibits transcription from the SV40 early promoter
    • Bryans, M., Kass, S., Servwright, C., and Adams, R. L. Vector methylation inhibits transcription from the SV40 early promoter. FEBS Lett., 309: 97-102, 1992.
    • (1992) FEBS Lett. , vol.309 , pp. 97-102
    • Bryans, M.1    Kass, S.2    Servwright, C.3    Adams, R.L.4
  • 37
    • 0022371467 scopus 로고
    • Very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
    • Boshart, M., Weber, F., Jahn, G., Dorsch-Hasler, K., Fleckenstein, B., and Schaffner, W A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus Cell, 41: 521-530, 1985.
    • (1985) Cell , vol.41 , pp. 521-530
    • Boshart, M.1    Weber, F.2    Jahn, G.3    Dorsch-Hasler, K.4    Fleckenstein, B.5    Schaffner, W.A.6
  • 38
    • 0022365333 scopus 로고
    • Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors
    • Keller, G., Paige, C., Gilboa, E., and Wagner, E. F. Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors. Nature (Lond.), 318: 149-154, 1985
    • (1985) Nature (Lond.) , vol.318 , pp. 149-154
    • Keller, G.1    Paige, C.2    Gilboa, E.3    Wagner, E.F.4
  • 39
    • 0020582124 scopus 로고
    • Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
    • Mann, R., Mulligan, R. C., and Baltimore, D. Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell, 33: 153-159, 1983.
    • (1983) Cell , vol.33 , pp. 153-159
    • Mann, R.1    Mulligan, R.C.2    Baltimore, D.3
  • 40
    • 0021924493 scopus 로고
    • Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene
    • Miller, A. D., Law, M-F., and Verma, I. M. Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene. Mol. Cell. Biol., 5: 431-437, 1985.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 431-437
    • Miller, A.D.1    Law, M.-F.2    Verma, I.M.3
  • 41
    • 0026478814 scopus 로고
    • Mode of action of the spiroplasma CpG methylase M.SssI
    • Renbaum, P. and Razin, A. Mode of action of the spiroplasma CpG methylase M.SssI. FEBS Lett., 313: 243-247, 1992.
    • (1992) FEBS Lett. , vol.313 , pp. 243-247
    • Renbaum, P.1    Razin, A.2
  • 42
    • 0025220507 scopus 로고
    • Cloning, characterization, and expression in Escherichia coli of the gene coding for the CpG DNA methylase from Spiroplasma sp. strain MQ1(M.SssI)
    • Renbaum, P., Abrahamove, D , Fainsod, A., Wilson, G. G., Rottem, S., and Razin, A Cloning, characterization, and expression in Escherichia coli of the gene coding for the CpG DNA methylase from Spiroplasma sp. strain MQ1(M.SssI). Nucleic Acids Res., 18: 1145-1152, 1990.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1145-1152
    • Renbaum, P.1    Abrahamove, D.2    Fainsod, A.3    Wilson, G.G.4    Rottem, S.5    Razin, A.6
  • 44
    • 0023270085 scopus 로고
    • Hypermethylation of the 5′ region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies
    • Baylin, S. B., Fearon, E R., Vogelstein, B., de Bustros, A , Sharkis, S. J., Burke, P. J., Staal, S. P., and Nelkin, B. D. Hypermethylation of the 5′ region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies. Blood, 70: 412-417, 1987.
    • (1987) Blood , vol.70 , pp. 412-417
    • Baylin, S.B.1    Fearon, E.R.2    Vogelstein, B.3    De Bustros, A.4    Sharkis, S.J.5    Burke, P.J.6    Staal, S.P.7    Nelkin, B.D.8
  • 45
    • 0025219432 scopus 로고
    • The role of DNA methylation in cancer
    • Jones, P. A., and Buckley, J. D. The role of DNA methylation in cancer. Adv. Cancer Res., 54: 1-23, 1990.
    • (1990) Adv. Cancer Res. , vol.54 , pp. 1-23
    • Jones, P.A.1    Buckley, J.D.2
  • 47
    • 0026556867 scopus 로고
    • Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer
    • Makos, M., Nelkin, B. D., Lerman, M. I., Latif, F., Zbar, B , and Baylin, S. B Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer Proc. Natl. Acad. Sci USA, 89: 1929-1933, 1992.
    • (1992) Proc. Natl. Acad. Sci USA , vol.89 , pp. 1929-1933
    • Makos, M.1    Nelkin, B.D.2    Lerman, M.I.3    Latif, F.4    Zbar, B.5    Baylin, S.B.6
  • 48
    • 0027207886 scopus 로고
    • Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors
    • Makos, M., Nelkin, B. D , Reiter, R. E., Gnarra, J. R., Brooks, J , Isaacs, W., Linehan, M , and Baylin, S B. Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors. Cancer Res., 53. 2719-2722, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 2719-2722
    • Makos, M.1    Nelkin, B.D.2    Reiter, R.E.3    Gnarra, J.R.4    Brooks, J.5    Isaacs, W.6    Linehan, M.7    Baylin, S.B.8
  • 50
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird, A. P. CpG-rich islands and the function of DNA methylation. Nature (Lond.), 321: 209-213, 1986.
    • (1986) Nature (Lond.) , vol.321 , pp. 209-213
    • Bird, A.P.1
  • 51
    • 0025145277 scopus 로고
    • 5-Methylcytosine as an endogenous mutagen in human LDL receptor and p53 genes
    • Washington DC
    • Rideout, III, W. M., Coetzee, G. A , Olumi, A F., and Jones, P. A. 5-Methylcytosine as an endogenous mutagen in human LDL receptor and p53 genes. Science (Washington DC), 249: 1288-1290, 1990.
    • (1990) Science , vol.249 , pp. 1288-1290
    • Rideout III, W.M.1    Coetzee, G.A.2    Olumi, A.F.3    Jones, P.A.4
  • 52
    • 0023853921 scopus 로고
    • The CpG dinucletide and human genetic diseases
    • Cooper, D. N., and Youssoufian, H. The CpG dinucletide and human genetic diseases. Hum. Genet., 78: 151-155, 1988.
    • (1988) Hum. Genet. , vol.78 , pp. 151-155
    • Cooper, D.N.1    Youssoufian, H.2
  • 53
  • 54
    • 0023176797 scopus 로고
    • Kinetic and catalytic mechanism of HhaI methyltransferase
    • Wu, J. C , and Santi, D. V Kinetic and catalytic mechanism of HhaI methyltransferase J Biol Chem., 262. 4778-4786, 1987.
    • (1987) J Biol Chem. , vol.262 , pp. 4778-4786
    • Wu, J.C.1    Santi, D.V.2
  • 55
    • 0023718544 scopus 로고
    • 5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylase
    • Osterman, D G , DePillis, G. D., Wu, J. C., Matsuda, A , and Santi, D. V. 5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylase. Biochemistry, 27: 5204-5210, 1988.
    • (1988) Biochemistry , vol.27 , pp. 5204-5210
    • Osterman, D.G.1    DePillis, G.D.2    Wu, J.C.3    Matsuda, A.4    Santi, D.V.5
  • 56
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Washington DC
    • Nowell, P C The clonal evolution of tumor cell populations. Science (Washington DC), 194 23-28, 1976.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1


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