SCOPUS 정보 검색 플랫폼

Volumn 10, Issue 3, 2002, Pages 493-500

Synthesis and enzymatic activation of N-[Nα-(4-amino-4-deoxypteroyl)-Nδ- hemiphthaloyl-L-ornithiny]-L-phenylalanine, a candidate for Antibody-Directed Enzyme Prodrug Therapy (ADEPT)

(2) Wright, Joel E b Rosowsky, Andre a

a HARVARD MEDICAL SCHOOL (United States)

b NONE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE A; DIHYDROFOLIC ACID; N [NALPHA (4 AMINO 4 DEOXYPTEROYL)NDELTA HEMIPHTHALOYLORNITHINY]PHENYLALANINE; NALPHA (4 AMINO 4 DEOXYPTEROYL) NDELTA HEMIPHTHALOYLORNITHINE; PHENYLALANINE DERIVATIVE; PRODRUG; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; ANTINEOPLASTIC AGENT; CARBOXYPEPTIDASE; DIHYDROFLAVANOL 4 REDUCTASE; DIHYDROFLAVANOL 4-REDUCTASE; DIPEPTIDE; ENZYME INHIBITOR; N (N (4 AMINO 4 DEOXYPTEROYL) N HEMIPHTHALOYL ORNITHINY) PHENYLALANINE; N-(N-(4-AMINO-4-DEOXYPTEROYL)-N-HEMIPHTHALOYL-ORNITHINY)-PHENYLALANINE;

ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ARTICLE; ASSAY; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVATION; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; LYMPHOBLAST; SPECTROPHOTOMETRY; STOICHIOMETRY; ANIMAL; CATTLE; CELL CULTURE; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BOVINAE;

ALCOHOL OXIDOREDUCTASES; ANIMALS; ANTINEOPLASTIC AGENTS; CARBOXYPEPTIDASES; CARBOXYPEPTIDASES A; CATTLE; CELL DIVISION; DIPEPTIDES; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0036155243 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(01)00298-X Document Type: Article

Times cited : (10)

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