Distinctions in agonist and antagonist specificity conferred by anionic residues of the nicotinic acetylcholine receptor

Journal of Biological Chemistry

Volumn 273, Issue 21, 1998, Pages 12758-12765

  Osaka, Hitoshi ^a   Sugiyama, Naoya ^a,b   Taylor, Palmer ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ASPARTIC ACID; CARBACHOL; NICOTINIC RECEPTOR; PROADIFEN; TUBOCURARINE CHLORIDE;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; INHIBITION KINETICS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR OCCUPANCY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; CARBACHOL; CELL LINE; CHOLINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PROADIFEN; RECEPTORS, NICOTINIC; SEQUENCE ALIGNMENT; TUBOCURARINE; TYROSINE;

EID: 0032557561     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.21.12758     Document Type: Article

References (39)

1. Unwin, N. (1993) J. Mol. Biol. 229, 1101-1124
2. Karlin, A., and Akabas, M. H. (1995) Neuron 15, 1231-1244
3. Hucho, F., Tsetlin V. I., and Machold, J. (1996) Eur. J. Biochem. 239, 539-557
4. Changeux, J-P. (1995) Biochem. Soc. Trans. 23, 195-205
5. Cohen, J. B., Blanton, M. P., Chiara, D. C., Sharp, S. D., and White, B. H. (1992) J. Cell. Biochem. 16E, 217 (abstr.)
6. Sine, S. M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9436-9440
7. Czajkowski, C., Kaufmann, C., and Karlin, A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6285-6289
8. O' Leary, M. E., Filatov, G. N., and White M. M. (1994) Am. J. Physiol. 266, C648-C653
9. Sine, S. M., Kreienkamp, H.-J., Bren, N., Maeda, R., and Taylor, P. (1995) Neuron 15, 205-211
10. Prince, R. J., and Sine, S. M. (1996) J. Biol. Chem. 271, 25770-25777
11. Sine, S. M. (1997) J. Biol. Chem. 272, 23521-23527
12. Bren N., and Sine, S. M. (1997) J. Biol. Chem. 272, 30793-30798
13. Taigelny, I., Sugiyama, N., Sine, S. M., and Taylor, P. (1997) Biophys. J. 73, 52-66
14. Dougherty, D. A. (1996) Science 271, 163-168
15. Segal, D. M., Padlan, E. A., Cohen, G. H., Rudikoff, S., Potter, M., and Davies, D. R. (1974) Proc. Natl. Acad. Sci. U. S. A. 71, 4295-4302
16. Sussman, J. L., Harel, M., Frolow, F., Oefner, C., Goldman, A., Toker, L., and Silman, I. (1991) Science 253, 872-879
17. Czajkowski, C., and Karlin, A. (1991) J. Biol. Chem. 266, 22603-22612
18. Czajkowski, C., and Karlin, A. (1995) J. Biol. Chem. 270, 3160-3164
19. Martin, M., Czajkowski, C., and Karlin, A. (1996) J. Biol. Chem. 271, 13497-13503
20. Sugiyama, N., Boyd A. E., and Taylor, P. (1996) J. Biol. Chem. 271, 26575-26581
21. Sine, S. M., and Taylor, P. (1979) J. Biol. Chem. 254, 3315-3325
22. Sine, S. M., and Taylor, P. (1981) J. Biol. Chem. 256, 6692-6699
23. Martin, M. D., and Karlin, A. (1997) Biochemistry 36, 10742-10750
24. Weber, M., and Changeux, J.-P. (1974) Mol. Pharmacol. 10, 15-34
25. Sine, S. M., and Taylor, P. (1982) J. Biol. Chem. 257, 8106-8114
26. Taylor, P., Brown, R. D., and Johnson, D. A. (1983) Current Top. Membr. Transp. 18, 407-444
27. Boyd, N. D, and Cohen, J. B. (1984) Biochemistry 23, 4023-4033
28. Sine, S. M., and Claudio, T. (1991) J. Biol. Chem. 266, 19369-19377
29. Sine, S. M., and Claudio, T. (1991) J. Biol. Chem. 266, 13679-13689
30. Auerbach, A. (1993) J. Physiol. 461, 339-378
31. Pressman, D., Grossberg, A. C., Pence, L. H., and Pauling L. (1946) J. Am. Chem. Soc. 68, 250-255
32. Radić, Z., Kirchhoff, P. D., Quinn, D. M., McCammon J. A., and Taylor, P. (1997) J. Biol. Chem. 272, 23265-23277
33. Galzi, J.-L., and Changeux, J.-P. (1994) Curr. Opin. Struct. Biol. 4, 554-565
34. Taylor, P., and Radić, Z. (1994) Annu. Rev. Pharmacal. Toxicol. 34, 281-320
35. Shaffertnan, A., Ordentlich, A., Barak, D., Stein, D., Ariel, N., and Velan, B. (1996) Biochem. J. 318, 833-840
36. Staufier D. A, and Karlin A (1994) Biochemistry 33, 6840-6849
37. Pauling, P., and Petcher, T. J. (1973) Chem. Biol. Interact. 6, 351-365
38. Sine, S. M., Quiram, P., Papanikolaou, F., Kreienkamp, H.-J., and Taylor, P. (1994) J. Biol. Chem. 269, 8808-8816
39. Akk, G., Sine, S., and Auerbach, A. (1996) J. Physiol. 496, 185-196