Biotinylation of substituted cysteines in the nicotinic acetylcholine receptor reveals distinct binding modes for α-bungarotoxin and erabutoxin a

Journal of Biological Chemistry

Volumn 275, Issue 29, 2000, Pages 22452-22460

  Spura, Armin ^a   Riel, Ryan U ^a   Freedman, Neal D ^a   Agrawal, Shantanu ^a   Seto, Christopher ^b   Hawrot, Edward ^a  

^a BROWN UNIVERSITY   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; CYSTEINE; ERABUTOXIN A; NICOTINIC RECEPTOR; PHENYLALANINE; PROLINE; TRYPTOPHAN; TYROSINE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; BIOTINYLATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RECEPTOR BINDING; TOXIN ANALYSIS;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BUNGAROTOXINS; CYSTEINE; ERABUTOXINS; MICE; PROTEIN BINDING; RECEPTORS, NICOTINIC; SIGNAL TRANSDUCTION;

EID: 0034698055     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M001283200     Document Type: Article

References (49)

1. Karlin, A., and Akabas, M. H. (1995) Neuron 15, 1231-1244
2. White, S. H. (ed.) (1994) Membrane Structure: Methods in Physiology, Oxford University Press Inc., New York
3. Bennett, J. A., and Dingledine, R. (1995) Neuron 14, 373-384
4. Anand, R., Bason, L., Saedi, M. S., Gerzanich, V., Peng, X., and Lindstrom, J. (1993) Biochemistry 32, 9975-9984
5. Chavez, R. A., and Hall, Z. W. (1992) J. Cell Biol. 116, 385-393
6. Pedemonte, C. H., Sachs, G., and Kaplan, J. H. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9789-9793
7. Olivares, L., Aragon, C., Gimenez, C., and Zafra, F. (1997) J. Biol. Chem. 272, 1211-1217
8. Bennett, E. R., and Kanner, B. I. (1997) J. Biol. Chem. 272, 1203-1210
9. Unwin, N. (1993) Cell 72, 31-41
10. Gallivan, J. P., Lester, H. A., and Dougherty, D. A. (1997) Chem. Biol. 4, 739-749
11. Saedi, M., Anand, R., Conroy, W., and Lindstrom, J. (1990) FEBS Lett. 267, 55-59
12. Akabas, M. H., Stauffer, D. A., Xu, M., and Karlin, A. (1992) Science 258, 307-310
13. Stauffer, D. A., and Karlin, A. (1994) Biochemistry 33, 6840-6849
14. Sine, S. M. (1997) J. Biol. Chem. 272, 23521-23527
15. Machold, J., Weise, C., Utkin, Y., Tsetlin, V., and Hucho, F. (1995) Eur. J. Biochem. 234, 427-430
16. Spura, A., Russin T. S., Freedman N. D., Grant M., McLaughlin J. T., and Hawrot, E. (1999) Biochemistry 38, 4912-4921
17. McLaughlin, J. T., Hawrot, E., and Yellen, G. (1995) Biochem. J. 310, 765-769
18. Sigal, G., Mammen, M., Dahmann, G., and Whitesides, G. (1996) J. Am. Chem. Soc. 118, 3789-3800
19. Becker, J. M., Wilchek, M., and Katchalski, E. (1971) Proc. Natl. Acad. Sci. U. S. A. 68, 2604-2607
20. Currier, S. F., and Mautner, H. G. (1977) Biochemistry 16, 1944-1948
21. Bruice, T., and Kenyon, G. (1982) J. Protein Chem. 1, 47-58
22. Sine, S., and Taylor, P. (1981) J. Biol. Chem. 256, 6692-6699
23. Kreienkamp, H.-J., Sine, S. M., Maeda, R. K., and Taylor, P. (1994) J. Biol. Chem. 269, 8108-8114
24. Laemmli, U. K. (1970) Nature 227, 680-685
25. Chase, B. A., Holliday, J., Reese, J. H., Chun, L. L., and Hawrot, E. (1987) Neuroscience 3, 959-976
26. Sine, S., and Taylor, P. (1978) J. Biol. Chem. 254, 3315-3325
27. Damle, V. N., McLaughlin, M., and Karlin, A. (1978) Biochem. Biophys. Res. Commun. 84, 845-851
28. De Souza-Otero, A., and Hamilton, S. L. (1984) Biochemistry 23, 2321-2328
29. Criado, M., Sarin, V., Fox, J. L., and Lindstrom, J. (1986) Biochemistry 25, 2839-2846
30. Ackermann, E. J., and Taylor, P. (1997) Biochemistry 36, 12836-12844
31. Ackermann, E. J., Ang, E. T.-H., Kanter, J. R., Tsigelny, I., and Taylor, P. (1998) J. Biol. Chem. 273, 10958-10965
32. Grunewald, M., Bendahan, A., and Kanner, B. I. (1998) Neuron 21, 623-632
33. Boileau, A. J., Evers, A. R., Davis, A. F., and Czajkowski, C. (1999) J. Neurosci. 19, 4847-4854
34. Pascual, J. M., and Karlin, A. (1998) J. Gen. Physiol. 111, 717-739
35. Schelte, P., Boeckler, C., Frisch, B., and Schuber, F. (2000) Bioconjugate Chem. 11, 118-123
36. Basus, V., Song, G., and Hawrot, E. (1993) Biochemistry 32, 12290-12298
37. Keller, S. H., Kreienkamp, H.-J., Kawanishi, C, and Taylor, P. (1995) J. Biol. Chem. 270, 4165-4171
38. Zhang, H., and Karlin, A. (1997) Biochemistry 36, 15
39. Levandoski, M. M., Lin, Y., Moise, L., McLaughlin, J. T., Cooper, E., and Hawrot, E. (1999) J. Biol. Chem. 274, 26113-26119
40. Tremeau, O., Lemaire, C., Drevet, P., Pinkasfeld, S., Ducancel, F., Boulain, J. C., and Menez, A. (1995) J. Biol. Chem. 270, 9362-9369
41. Love, R. A., and Stroud, R. M. (1986) Protein Eng. 1, 37-46
42. Harel, M., and Sussman, J. L. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 9031-9035
43. Miyazawa, A., Fujiyoshi, Y., Stowell, M., and Unwin, N. (1999) J. Mol. Biol. 288, 765-786
44. Cerveòansky, C., Engstrom, A., and Karlsson, E. (1994) Biochim. Biophys. Acta 1199, 1-5
45. Sussman, J. L., and Silman, I. (1991) Science 253, 872-879
46. Bourne, Y., Taylor, P., and Marchot, P. (1995) Cell 83, 503-512
47. Harel, M., Kleywegt, G. J., Ravelli, R. B. G., Silman, I., and Sussman, J. L. (1995) Structure 3, 1355-1366
48. Lentz, T., and Wilson, P. (1988) Int. Rev. Neurobiol. 29, 117-160
49. Rosenthal, J. A., Levandoski, M. M., Chang, B., Potts, J. F., Shi, Q. L., and Hawrot, E. (1999) Biochemistry 38, 7847-55