Unique motif for nucleolar retention and nuclear export regulated by phosphorylation

Molecular and Cellular Biology

Volumn 22, Issue 4, 2002, Pages 1126-1139

  Catez, Frédéric ^a   Erard, Monique ^a   Schaerer Uthurralt, Nathalie ^a   Kindbeiter, Karine ^a   Madjar, Jean Jacques ^a   Diaz, Jean Jacques ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GLUTATHIONE TRANSFERASE; NUCLEOLAR PROTEIN; PROLINE; PROTEIN US11; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; COMPUTER MODEL; CONTROLLED STUDY; CYTOPLASM; ENERGY; ENZYME PURIFICATION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MICROINJECTION; MUTAGENESIS; NONHUMAN; NUCLEAR PORE COMPLEX; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TEMPERATURE DEPENDENCE;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL NUCLEOLUS; GLUTATHIONE TRANSFERASE; HELA CELLS; HUMANS; MICROINJECTIONS; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; SERUM ALBUMIN, BOVINE; VIRAL PROTEINS;

DNA VIRUSES; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 0036148545     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.4.1126-1139.2002     Document Type: Article

References (56)

1. The road to ribosomes. Filling potholes in the export pathway
2. Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase
3. In situ hybridization and immunoelectron microscope analyses of the Us11 gene of herpes simplex virus type 1 for transient expression
4. Definition of a consensus transportin-specific nucleocytoplasmic transport signal
5. Nuclear localization signals (NLS)
6. The Rev protein is able to transport to the cytoplasm small nucleolar RNAs containing a Rev binding element
7. The herpes simplex virus US11 protein effectively compensates for the γ1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2
8. Sequence requirements for synthetic peptide-mediated translocation to the nucleus
9. Determination of the functional domains involved in nucleolar targeting of nucleolin
10. Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism
11. Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins
12. Posttranscriptional transactivation of human retroviral envelope glycoprotein expression by herpes simplex virus Us11 protein
13. Fine-structure map of the human ribosomal protein gene RPS14
14. The herpes simplex virus type 1 Us11 gene product is a phosphorylated protein found to be nonspecifically associated with both ribosomal subunits
15. Herpes simplex virus Us11 protein enhances recovery of protein synthesis and survival in heat shock treated HeLa cells
16. The herpes simplex virus 1 Us11 protein cooperates with suboptimal amounts of human immunodeficiency virus type 1 (HIV-1) Rev protein to rescue HIV-1 production
17. Functional architecture in the cell nucleus
18. The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
19. Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-beta
20. Analogs of staurosporine: Potential anticancer drugs?
21. Transport between the cell nucleus and the cytoplasm
22. Nucleocytoplasmic transport
23. The DNA sequence coding for the 5′ untranslated region of herpes simplex type 1 ICP22 mRNA mediates high level of gene expression
24. Characteristics of the binding of rotenone in the respiratory chain and the inhibition sites of amytal and piericidin A
25. Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells
26. Telomeres, the nucleolus and aging
27. Sequence requirements for nuclear location of simian virus 40 large-T antigen
28. Cleavage of structural proteins for the assembly of the head of bacteriophage T4
29. Like attracts like: Getting RNA processing together in the nucleus
30. Exportin 4: A mediator of a novel nuclear export pathway in higher eukaryotes
31. In vivo interaction of nucleophosmin/B23 and protein C23 for cell cycle progression in HeLa cells
32. Nucleolar and nuclear localization properties of a herpesvirus bZIP oncoprotein
33. Identification of a cryptic nucleolar-localization signal in MDM2
34. Spot position of rat liver ribosomal proteins by four different two-dimensional electrophoreses in polyacrylamide gel
35. Nucleocytoplasmic shuttling signals: Two for the price of one
36. Maturation and intranuclear transport of preribosomes requires noc proteins
37. Protein dynamics: Implications for nuclear architecture and gene expression
38. Identification of the nucleolar targeting signal of human angiogenin
39. Transport of proteins and RNAs in and out of the nucleus
40. The nucleolus: An old factory with unexpected capabilities
41. The plurifunctional nucleolus
42. High mobility of proteins in the mammalian cell nucleus
43. Localization of viral-specific 21kDa protein in nucleoli of herpes simplex infected cells
44. The nucleolus is the site of Borna disease virus RNA transcription and replication
45. Herpes simplex viruses and their replication
46. Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: Mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitro
47. The herpes simplex virus 1 RNA binding protein Us11 is a virion component and associates with ribosomal 60S subunits
48. Ribozymes in the nucleolus
49. Distinct domains in herpes simplex virus type 1 US11 protein mediate posttranscriptional transactivation of human T-lymphotropic virus type I envelope glycoprotein gene expression and specific binding to the Rex responsive element
50. Structure and function of the nucleolus
51. Phosphorylation of herpes simplex virus type 1 Us11 protein is independent of viral genome expression
52. Sequence requirements for nucleolar localization of human T-cell leukemia virus type I pX protein, which regulates viral RNA processing
53. A structural basis for substrate specificities of protein Ser/Thr kinases: Primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulindependent kinase II, CDK5, and Erk1
54. Identification of a signal for rapid export of proteins from the nucleus
55. A kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1
56. Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev