A kinase activity associated with Simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1

Molecular and Cellular Biology

Volumn 19, Issue 4, 1999, Pages 2791-2802

  Zhai, Weiguo ^a   Comai, Lucio ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UPSTREAM BINDING FACTOR; VIRUS LARGE T ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CARBOXY TERMINAL SEQUENCE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIMIAN VIRUS; STOICHIOMETRY; TRANSACTIVATION; TRANSCRIPTION INITIATION;

DNA VIRUSES; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0032915372     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.4.2791     Document Type: Article

References (64)

1. cdk2. J. Virol. 67:6551-6557.
2. Anderson, M. M., J. Chen, C. N. Cole, and S. E. Conrad. 1996. Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites. J. Virol. 70:6304-6313.
3. Bell, S. P., R. M. Learned, H.-M. Jantzen, and R. Tjian. 1988. Functional cooperatively between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. Science 241:1192-1197.
4. Berger, L. C., D. B. Smith, I. Davidson, J. J. Hwong, E. Fanning, and A. G. Wildeman. 1996. Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control. J. Virol. 70:1203-1212.
5. Boyle, W. J., P. van der Geer, and T. Hunter. 1991. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201:110-149.
6. Bradley, M. K., J. D. Griffin, and D. M. Livingston. 1982. Relationship of oligomerization to enzymatic and DNA-binding properties of the SV40 large T antigen. Cell 28:125-134.
7. Brinster, R. L., H. Y. Chen, A. Messing, T. van Dyke, A. J. Levine, and R. D. Palmiter. 1984. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 37:367-379.
8. Cao, S. X., H. Mishoe, J. Elion, P. E. Berg, and A. N. Schechter. 1989. Activation of the human epsilon-and beta-globin promoters by SV40 T antigen. Biochem. J. 258:769-776.
9. Cegielska, A., I. Moarefi, E. Fanning, and D. M. Virshup. 1994. T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123. J. Virol. 68:269-275.
10. Chen, H., J. Campisi, and R. Padmanabhan. 1996. SV40 large T antigen transactivates the human cdc2 promoter by inducing a CCAAT box binding factor. J. Biol. Chem. 271:13959-13967.
11. Comai, L., N. Tanese, and R. Tjian. 1992. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell 68:965-976.
12. Comai, L., J. C. B. M. Zomerdijk, H. Beckmann, S. Zhou, A. Admon, and R. Tjian. 1994. Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. Science 266:1966-1972.
13. Conzen, S. D., and C. N. Cole. 1994. The transforming proteins of simian virus 40. Semin. Virol. 5:349-356.
14. Damania, B., and J. C. Alwine. 1996. TAF-like function of SV40 large-T antigen. Genes Dev. 10:1369-1381.
15. Damania, B., P. Lieberman, and J. C. Alwine. 1998. Simian virus 40 large T antigen stabilizes the TATA-binding protein-TFIIA complex on the TATA element. Mol. Cell. Biol. 18:3926-3935.
16. Damania, B., R. Mital, and J. C. Alwine. 1998. Simian virus 40 large T antigen interacts with human TFIIB-related factor and small nuclear RNA-activating protein complex for transcriptional activation of TATA-containing polymerase III promoters. Mol. Cell. Biol. 18:1331-1338.
17. DeCaprio, J. A., J. W. Ludlow, J. Figge, J. Y. Shew, C. M. Huang, W. H. Lee, E. Marsilio, E. Paucha, and D. M. Livingston. 1988. SV40 large tumor antigen forms a specific complex with the product of retinoblastoma susceptibility gene. Cell 54:275-283.
18. Dunnick, W., L. Elenich, K. Cunningham, C. Chris, and L. Claflin. 1995. Tumorigenesis in mice with an SV40 T antigen transgene driven by the immunoglobulin gamma 1 heavy chain germline promoter. Curr. Top. Microbiol. Immunol. 194:163-169.
19. Dyson, N., K. Buchkovich, P. Whyte, and E. Harlow. 1989. The cellular 107k protein that binds to adenovirus E1A also associates with the large T antigen of SV40 and JC virus. Cell 58:249-255.
20. Dyson, N., P. Guida, K. Munger, and E. Harlow. 1992. Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. J. Virol. 66:6893-6902.
21. Eckner, R., J. W. Ludlow, N. L. Lill, E. Oldread, Z. Arany, N. Modjtahedi, J. A. Decaprio, D. M. Livingston, and J. A. Morgan. 1996. Association of p300 and CBP with simian virus 40 large T antigen. Mol. Cell. Biol. 16:3454-3464.
22. Fanning, E., and R. Knippers. 1992. Structure and function of simian virus 40 large tumor antigen. Annu. Rev. Biochem. 61:55-85.
23. Gallo, G. J., M. C. Gruda, J. R. Manuppello, and J. C. Alwine. 1990. Activity of simian DNA-hinding factors is altered in the presence of simian virus 40 (SV40) early proteins: characterization of factors binding to elements involved in activation of the SV40 late promoter. J. Virol. 64:173-184.
24. Garcia-Martinez, L. F., G. Mavankal, J. M. Neveu, W. S. Lane, D. Ivanov, and R. B. Gaynor. 1997. Purification of a tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription. EMBO J. 16:2836-2850.
25. Gilinger, G., and J. C. Alwine. 1993. Transcriptional activation by simian virus 40 large T antigen: requirements for simple promoter structures containing either TATA or initiator elements with variable upstream factor binding sites. J. Virol. 67:6682-6688.
26. Glibetic, M., L. Taylor, D. Larson, R. Hannan, B. Sells, and L. Rothblum. 1995. The RNA polymerase I transcription factor UBF is the product of a primary response gene. J. Biol. Chem. 270:4209-4212.
27. Gotz, C., M. G. Koenig, O.-G. Issinger, and M. Montenarh. 1995. A casein-kinase-2 related protein kinase is tightly associated with the large-T antigen of simian virus 40. Eur. J. Biochem. 233:327-334.
28. Griffin, J. D., G. Spangler, and D. M. Livingston. 1979. Protein kinase activity associated with simian virus 40 T antigen. Proc. Natl. Acad. Sci. USA 76:2610-2614.
29. Gruda, M., and J. C. Alwine. 1991. Simian virus 40 (SV40) transcriptional activation mediated through the Oct/SPH region of the SV40 late promoter. J. Virol. 65:3553-3558.
30. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
31. Hempel, W. M., A. H. Canvanaugh, R. D. Hannan, L. Taylor, and L. I. Rothblum. 1996. The species-specific RNA polymerase I transcription factor SL1 binds to the upstream binding factor. Mol. Cell. Biol. 16:557-563.
32. Herrmann, C. H., L. K. Su, and E. Harlow. 1991. Adenovirus E1A is associated with a serine/threonine protein kinase. J. Virol. 65:5848-5859.
33. Inoue, T., Y. Hirabayashi, H. Mitsui, Y. Furuta, Y. Suda, S. I. Aizawa, and Y. Ikawa. 1994. Experimental model for MDS-like myelodysplasia in transgenic mice harboring the SV40 large T antigen under an immunoglobulin enhancer. Leukemia 8:S202-S205.
34. Jantzen, H.-M., A. Admon, S. P. Bell, and R. Tjian. 1990. Nuclear transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins. Nature 344:830-836.
35. Jantzen, H.-M., A. M. Chow, D. S. King, and R. Tjian. 1992. Multiple domains of the RNA polymerase I activator hUBF interacts with the TATA-binding protein complex hSL1 to mediate transcription. Genes Dev. 6:1950-1963.
36. Keller, J. M., and J. C. Alwine. 1984. Activation of the SV40 late promoter: direct effects of T antigen in the absence of viral DNA replication. Cell 36:381-389.
37. Keller, J. M., and J. C. Alwine. 1985. Sequences in the simian virus 40 late promoter required for T-antigen-mediated trans activation. Mol. Cell. Biol. 5:1859-1869.
38. Kumar, T. R., K. E. Graham, S. L. Asa, and M. J. Low. 1998. Simian virus 40 T antigen induced gonadotroph adenomas: a model of human null cell adenomas. Endocrinology 139:3342-3351.
39. Learned, R. M., T. K. Learned, M. M. Haltiner, and R. Tjian. 1986. Human rRNA transcription is modulated by the coordinate binding of two factors to an upstream control element. Cell 45:847-857.
40. Learned, R. M., and R. Tjian. 1982. In vitro transcription of human ribosomal RNA genes by RNA polymerase I. J. Mol. Appl. Genet. 1:575-584.
41. Levine, A. J. 1990. The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses. Virology 177:419-426.
42. Lill, N., M. J. Tevethia, R. Eckner, D. M. Livingston, and N. Modjtahedi. 1997. p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen. J. Virol. 71:129-137.
43. Loeken, M. R., G. Khoury, and J. Brady. 1986. Stimulation of the adenovirus E2 promoter by simian virus 40 T antigen or E1A occurs by different mechanisms. Mol. Cell. Biol. 6:2020-2026.
44. Ludlow, J. W. 1993. Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53. FASEB J. 7:866-871.
45. Meijer, L. 1996. Chemical inhibitors of cyclin-dependent kinases. Trends Cell Biol. 6:393-397.
46. Muller, E., and K. H. Scheidtmann. 1995. Purification and characterization of a protein kinase which is activated by SV40 large T antigen and phosphorylates the tumor suppressor protein p53. Oncogene 10:1175-1185.
47. O'Mahony, D. J., S. D. Smith, W. Xie, and L. I. Rothblum. 1992. Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2. Nucleic Acids Res. 20:1301-1308.
48. O'Mahony, D. J., W. Xie, S. D. Smith, H. A. Singer, and L. I. Rothblum. 1992. Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. J. Biol. Chem. 267:35-38.
49. Paule, M. R. 1998. Transcription of ribosomal RNA genes by eukaryotic RNA polymerase I. Springer-Verlag Inc., New York, N.Y.
50. Pines, J., and T. Hunter. 1990. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature 346:760-763.
51. Prives, C., J. Bargonetti, P. N. Freidman, J. J. Manfredi, and E. H. Wang. 1993. Functional consequences of the interactions of the p53 tumor suppressor protein and SV40 large tumor antigen. Cold Spring Harbor Symp. Quant. Biol. 54:227-235.
52. Rice, P. W., and C. N. Cole. 1993. Efficient transcriptional activation of many simple modular promoters by simian virus 40 large T antigen. J. Virol. 67:6689-6697.
53. Scheidtmann, K. H., and A. Haber. 1990. Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53. J. Virol. 64:672-679.
54. Schreier, A. A., and J. Gruber. 1990. Viral T antigen interacts with cellular proto-oncogene and anti-oncogene products. J. Natl. Cancer Inst. 82:354-360.
55. Shibata, M. A., C. L. Jorcyk, M. L. Liu, K. Yoshidome, L. G. Gold, and J. E. Green. 1998. The C3(1)/SV40 T antigen transgenic mouse model of prostate and mammary cancer. Toxicol. Pathol. 26:177-182.
56. Simanis, V., and D. P. Lane. 1985. An immunopurification procedure for SV40 large-T antigen. Virology 144:88-100.
57. Tjian, R., and A. Robbins. 1979. Enzymatic activities associated with a purified simian virus 40 T antigen-related protein. Proc. Natl. Acad. Sci. USA 76:610-614.
58. CDK2 and cyclin A. Oncogene 8:195-202.
59. Tuao, J, W. Zhai, and L. Comai. 1999. Recruitment of TATA-binding protein-TAF, complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation. Mol. Cell. Biol. 19:2872-2879.
60. Voit, R., A. Kuhn, E. E. Sander, and I. Grummt. 1995. Activation of mammalian ribosomal gene transcription requires phosphorylation of the nuclear transcription factor UBF. Nucleic Acids Res. 23:2593-2599.
61. Voit, R., A. Schnapp, A. Kuhn, H. Rasenbauer, P. Hirschmann, H. G. Stunnenberg, and I. Grummt. 1992. The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation. EMBO J. 11:2211-2218.
62. Walser, A., and W. Deppert. 1986. The kinase activity of SV40 large T antigen is mediated by a cellular kinase. EMBO J. 5:883-889.
63. Zhai, W., J. Tuan, and L. Comai. 1997. SV40 large T antigen binds to the TBP-TAFI complex SL2 and coactivates ribosomal RNA transcription. Genes Dev. 11:1605-1617.
64. Zhai, W., and L. Comai. Unpublished data.