Polymorphisms of the angiotensinogen gene, the endothelial nitric oxide synthase gene, and the interleukin-1β gene promoter in women with idiopathic recurrent miscarriage

Molecular Human Reproduction

Volumn 8, Issue 1, 2002, Pages 95-100

  Hefler, Lukas A ^a,b   Tempfer, Clemens B ^a   Bashford, Michael T ^c   Unfried, Gertrud ^a   Zeillinger, Robert ^a   Schneeberger, Christian ^a   Koelbl, Heinz ^c   Nagele, Fritz ^a   Huber, Johannes C ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Angiotensinogen; Idiopathic recurrent miscarriage; Interleukin 1 ; Nos3; Polymorphism

Indexed keywords

ANGIOTENSINOGEN; ASPARTIC ACID; CYTOSINE; GLUTAMIC ACID; INTERLEUKIN 1BETA; NITRIC OXIDE SYNTHASE; OLIGONUCLEOTIDE; THYMINE;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DNA POLYMORPHISM; ENDOTHELIUM; EXON; FEMALE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HUMAN; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; NUCLEIC ACID HYBRIDIZATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RECURRENT DISEASE; SEQUENCE ANALYSIS; SPONTANEOUS ABORTION; STATISTICAL ANALYSIS;

ABORTION, HABITUAL; ADULT; ANGIOTENSINOGEN; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; INTERLEUKIN-1; MUTATION, MISSENSE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; POLYMORPHISM, GENETIC; PREGNANCY; PROMOTER REGIONS (GENETICS); VARIATION (GENETICS);

EID: 0036146840     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Inhibition of nitric oxide production rescues LPS-induced fetal abortion in mice
2. Allelic polymorphism in IL-1 beta and IL-1 receptor antagonist (IL-1Ra) genes in inflammatory bowel disease
3. Karyotype of the abortus in recurrent miscarriage
4. Linkage of the angiotensinogen gene to essential hypertension
5. Genetic determinants of type 2 diabetes
6. Immunocytochemical kininogens during the initial stages of the rat liver differentiation
7. Genetic hypofibrinolysis in complicated pregnancies
8. Early embryo loss is associated with local production of nitric oxide by decidual mononuclear cells
9. Endothelial-derived nitric oxide and angiotensinogen: Blood pressure and metabolism during mouse pregnancy
10. T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion
11. Evidence of a TH1 type response associated with recurrent miscarriage
12. Haplotypes of angiotensinogen in essential hypertension
13. Genetic control of blood pressure and the angiotensinogen locus
14. Hypercoagulable state mutation analysis in white patients with early first-trimester recurrent pregnancy loss
15. Genetics of hypertension: From experimental models to clinical applications
16. Endothelium-dependent vasodilation in hypertension: A review
17. Human trophoblast invasion and spiral artery transformation: The role of nitric oxide
18. Mutations in coagulation factors in women with unexplained late fetal loss
19. Increased risk for fetal loss in carriers of the factor V Leiden mutation
20. The L-arginine-nitric oxide pathway
21. T-786 C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
22. The effects of angiotensin II and specific angiotensin receptor blockers on embryonic cardiac development and looping patterns
23. The carriage of pro-inflammatory cytokine gene polymorphisms in recurrent pregnancy loss
24. Pathogenesis and genetics of pre-eclampsia
25. Hypertension, serum angiotensinogen, and molecular variants of the angiotensinogen gene among Nigerians
26. Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro
27. Early expression of all the components of the renin-angiotensin-system in human development
28. Enhanced expression of cytokines may play a fundamental role in the mechanisms of immunologically mediated recurrent spontaneous abortion
29. Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction
30. The renin-angiotensin system and its receptors
31. Genetic control of fertility and embryonic waste in the mouse: A role for angiotensinogen
32. Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: Cleavage of proteins with aspartate vs. glutamate at position 298
33. Angiotensin-converting enzyme gene polymorphism and cardiovascular endocrine system in coronary angiography patients
34. Interleukin 1 receptor antagonist polymorphism in women with idiopathic recurrent miscarriage
35. A molecular variant of angiotensinogen associated with preeclampsia
36. Bidirectional cytokine interaction in maternal-fetal relationship: Is successful pregnancy a TH2 phenomenon?
37. Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease
38. Primary habitual abortions are associated with high frequency of factor V'Leiden mutation
39. Mapping of the genes encoding human inducible and endothelial nitric oxide synthase (NOS2 and NOS3) to the pericentric region of chromosome 17 and to chromosome 7, respectively
40. The missense Glu298Asp variant of the endothelial nitric oxide synthase gene is strongly associated with placental abruption
41. Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with severe preeclampsia
42. Polymorphisms in biotransformation enzymes and the risk for recurrent early pregnancy loss