Endothelial-derived nitric oxide and angiotensinogen: Blood pressure and metabolism during mouse pregnancy

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 280, Issue 1 49-1, 2001, Pages

  Hefler, Lukas A ^a   Tempfer, Clemens B ^a   Moreno, Rene M ^a   O'Brien, William E ^a   Gregg, Anthony R ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Nitric oxide synthase gene Nos3

Indexed keywords

ANGIOTENSINOGEN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; FEMALE; GENOTYPE; KIDNEY FUNCTION; LIVER FUNCTION; METABOLIC REGULATION; MOUSE; MUTATION; NONHUMAN; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SOUTHERN BLOTTING;

EID: 0035017619     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.2001.280.1.r174     Document Type: Article

References (31)

1. Arngrimsson R, Hayward C, Nadaud S, Baldursdottir A, Walker JJ, Liston WA, Bjarnadottir RI, Brock DJ, Geirsson RT, Connor JM, and Soubrier F. Evidence for a familial pregnancy-induced hypertension locus in the eNOS-gene region. Am J Hum Genet 61: 354-362, 1997.
2. Arngrimsson R, Purandare S, Connor M, Walker JJ, Bjornsson S, Soubrier F, Kotelevtsev YF, Geirsson RT, and Bjornsson H. Angiotensinogen: a candidate gene involved in preeclampsia? Nat Genet 4: 114-115, 1993.
3. Clouston WM, Evans BA, Haralambidis J, and Richards RI. Molecular cloning of the mouse angiotensinogen gene. Genomics 2: 240-248, 1988.
4. Conrad KP and Benyo DF. Placental cytokines and the pathogenesis of preeclampsia. Am J Reprod Immunol 37: 240-249, 1997.
5. Cunningham F, MacDonald PC, Gant NF, Leveno KJ, Gilstrap LC, Hankins GD, and Clark SL. Hypertensive disorders in pregnancy. In: Williams Obstetrics. Stamford, CT: Appleton & Lange. 1997, p. 693-744.
6. Edwards DL, Arora CP, Bui DT, and Castro LC. Long-term nitric oxide blockade in the pregnant rat: effects on blood pressure and plasma levels of endothelin-1. Am J Obstet Gynecol 175: 484-488, 1996.
7. Gregg AR, Schauer A, Shi O, Liu Z, Lee CG, and O'Brien WE. Limb reduction defects in endothelial nitric oxide synthase-deficient mice. Am J Physiol Heart Circ Physiol 275: H2319-H2324, 1998.
8. Hayman R, Brockelsby J, Kenny L, and Baker P. Preeclampsia: the endothelium, circulating factor(s) and vascular endothelial growth factor. J Soc Gynecol Investig 6: 3-10, 1999.
9. Herrera PL, Harlan DM, and Vassalli P. A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF. Proc Natl Acad Sci USA 97: 279-284, 2000.
10. Huang PL, Huang Z, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, and Fishman MC Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377: 239-242, 1995.
11. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, and Lalouel JM. Molecular basis of human hypertension: role of angiotensinogen. Cell 71: 169-180, 1992.
12. Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, and Smithies O. Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci USA 92: 2735-2739, 1995.
13. Leiter EH, Prochazka M, and Shultz LD. Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice. J Immunol 138: 3224-3229, 1987.
14. Loeb WF and Quimby FW. The Clinical Chemistry of Laboratory Animals. Philadelphia, PA: Taylor & Francis, 1999.
15. Meneton P, Ichikawa I, Inagami T, and Schnermann J. Renal physiology of the mouse. Am J Physiol Renal Physiol 278: F339-F351, 2000.
16. Miyamoto Y, Saito Y, Kajiyama N, Yoshimura M, Shimasaki Y, Nakayama M, Kamitani S, Harada M, Ishikawa M, Kuwahara K, Ogawa E, Hamanaka I, Takahashi N, Kaneshige T, Teraoka H, Akamizu T, Azuma N, Yoshimasa Y, Yoshimasa T, Itoh H, Masuda I, Yasue H, and Nakao K. Endothelial nitric oxide synthase gene is positively associated with essential hypertension. Hypertension 32: 3-8, 1998.
17. Moncada S and Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 329: 2002-2012, 1993.
18. Murakami K and Fukamizu A. Transgenic and knockout models in renin-angiotensin system. Immunopharmacology 44: 1-7, 1999.
19. Reid IA, Morris BJ, and Ganong WF. The renin-angiotensin system. Annu Rev Physiol 40: 377-410, 1978.
20. Rochat RW, Koonin LM, Atrash HK, and Jewett JF. Maternal mortality in the United States: report from the Maternal Mortality Collaborative. Obstet Gynecol 72: 91-97, 1988.
21. Sharma K, Wang L, Zhu Y, DeGuzman A, Cao GY, Lynn RB, and Joseph SK. Renal type I inositol 1,4,5-trisphosphate receptor is reduced in streptozotocin-induced diabetic rats and mice. Am J Physiol Renal Physiol 276: F54-F61, 1999.
22. Shesely EG, Maeda N, Kim HS, Desai KM, Krege JH, Laubach VE, Sherman PA, Sessa WC, and Smithies OS. Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proc Natl Acad Sci USA 93: 13176-13181, 1996.
23. Smithies O and Kim HS. Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice. Proc Natl Acad Sci USA 91: 3612-3615, 1994.
24. Stockelman MG, Lorenz JN, Smith FN, Boivin GP, Sahota A, Tischfield JA, and Stambrook PJ. Chronic renal failure in a mouse model of human adenine phosphoribosyltransferase deficiency. Am J Physiol Renal Physiol 275: F154-F163, 1998.
25. Takimoto E, Ishida J, Sugiyama F, Horiguchi H, Murakami K, and Fukamizu A. Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen. Science 274: 995-998, 1996.
26. Tempfer C, Moreno RM, O'Brien WE, and Gregg AR. Genetic contributions of the endothelial nitric oxide synthase gene to ovulation and menopause in a mouse model. Fertil Steril 73: 1025-1031, 2000.
27. Tempfer C, Zeisler H, Hefler L, Schatten C, Husslein P, and Kainz C. Serum levels of ELAM-1, but not CD44, predict the clinical outcome of patients with preeclampsia. Hypertens Pregnancy 18: 45-55, 1999.
28. Vane JR, Anggard EE, and Botting RM. Regulatory functions of the vascular endothelium. N Engl J Med 323: 27-36, 1990.
29. Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C, Farrington PF, Ogasawara M, Suzumori K, and Tomoda S. A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 4: 59-61, 1993.
30. Wight E, Rung CF, Moreau P, Takase H, and Luscher TF. Chronic blockade of nitric oxide-synthase and endothelin receptors during pregnancy in the rat: effect on pregnancy outcome. J Soc Gynecol Investig 5: 132-139, 1998.
31. Zhou Y, Genbacev O, Damsky CH, and Fisher SJ. Oxygen regulates human cytotrophoblast differentiation and invasion: implications for endovascular invasion in normal pregnancy and in preeclampsia. J Reprod Immunol 39: 197-213, 1998.