Safety and immunogenicity in neonatal mice of a hyperattenuated Listeria vaccine directed against human immunodeficiency virus

Journal of Virology

Volumn 76, Issue 2, 2002, Pages 918-922

  Rayevskaya, M ^a   Kushnir, N ^a   Frankel, F R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; CD8 ANTIGEN; LISTERIA MONOCYTOGENES VACCINE; LIVE VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HOST RESISTANCE; HOST SUSCEPTIBILITY; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE SYSTEM; IMMUNOGENICITY; LISTERIA MONOCYTOGENES; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; VACCINATION;

EID: 0036138856     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.2.918-922.2002     Document Type: Article

References (27)

1. Exclusive Th2 primary effector function in spleens but mixed Th1/Th2 function in lymph nodes of murine neonates
2. The generation of Th memory in neonates versus adults: Prolonged primary Th2 effector function and impaired development of Th1 memory effector function in murine neonates
3. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
4. Actively acquired tolerance of foreign cells
5. Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
6. Cellular immune responses in neonates
7. Induction of TH1 and TH2 immunity in neonatal mice
8. Protective T-cell-based immunity induced in neonatal mice by a single replicative cycle of herpes simplex virus
9. Induction of cell-mediated immune responses to human immunodeficiency virus type 1 Gag protein by using Listeria monocytogenes as a live vaccine vector
10. Induction of human immunodeficiency virus (HIV)-specific CD8 T-cell responses by Listeria monocytogenes and a hyperattenuated Listeria strain engineered to express HIV antigens
11. IL-12, IFN-gamma, and T cell proliferation to measles in immunized infants
12. Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization
13. Immunity to intracellular bacteria
14. Newborns develop a Th1-type immune response to Mycobacterium bovis bacillus Calmette-Guerin vaccination
15. Preferential localization of effector memory cells in nonlymphoid tissue
16. d through interactions between a glutamine at P3 and pocket D
17. The ability of B cells and dendritic cells to present antigen increases during ontogeny
18. Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection
19. Systemic immunity and mucosal immunity are induced against human immunodeficiency virus Gag protein in mice by a new hyperattenuated strain of Listeria monocytogenes
20. Visualizing the generation of memory CD4 T cells in the whole body
21. Neonatal tolerance revisited: Turning on newborn T cells with dendritic cells
22. Induction of protective CTL responses in newborn mice by a murine retrovirus
23. Vaccination in the neonatal period and early infancy
24. Pathogenicity and immunogenicity of a Listeria monocytogenes strain that requires D-alanine for growth
25. Diminished HIV-specific CTL activity is associated with lower type 1 and enhanced type 2 responses to HIV-specific peptides during perinatal HIV infection
26. Cutting edge: Antilisterial activity of CD8+ T cells derived from TNF-deficient and TNF/perforin double-deficient mice
27. Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha