Structure and function of pore-forming β-barrels from bacteria

Journal of Molecular Microbiology and Biotechnology

Volumn 4, Issue 1, 2002, Pages 1-10

  Delcour, A H ^a  

^a University of Houston   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL TOXIN; HEMOLYSIN; OUTER MEMBRANE PROTEIN; POLYPEPTIDE; PORIN;

CONFERENCE PAPER; CRYSTALLOGRAPHY; DIFFUSION; ESCHERICHIA; NONHUMAN; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN STRUCTURE, FUNCTION AND VARIABILITY; PROTEIN TRANSPORT; RHODOBACTER; STAPHYLOCOCCUS;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL TOXINS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HEMOLYSIN PROTEINS; ION CHANNEL GATING; LIGANDS; MODELS, MOLECULAR; PORINS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS;

EID: 0036132540     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (98)

1. Evaluation of the rate constants of sugar transport through maltoporin (LamB) of Escherichia coli from the sugar-induced current noise
2. Study of sugar binding to the sucrose-specific ScrY channel of enteric bacteria using current noise analysis
3. Charged residues in surface-located loops influence voltage gating of porin from Haemophilus influenzae type b
4. Refolded outer membrane protein OmpA of Escherichia coli forms ion channels with two conductance states in planar lipid bilayers
5. Voltage-gating of Escherichia coli porin: A cysteine-scanning mutagenesis study of loop 3
6. One single lysine residue is responsible for the special interaction between polyphosphate and the outer membrane porin PhoE of Escherichia coli
7. Designed membrane channels and pores
8. TolC of Escherichia coli functions as an outer membrane channel
9. Fast and slow kinetics of porin channels from Escherichia coli reconstituted into giant liposomes and studied by patch-clamp
10. Electrophysiological characteristics of the PhoE porin channel from Escherichia coli. Implications for the possible existence of a superfamily of ion channels
11. High-conductance channel induced by the interaction of phage lambda with its receptor maltoporin
12. Structure of the lc and nmpC outer membrane porin genes of lambdoid bacteriophage
13. The β-barrel domain of FhuAΔ5-160 is sufficient for TonB-dependent FhuA activities of Escherichia coli
14. The amino terminus of Pseudomonas aeruginosa outer membrane OprF forms channels in lipid bilayer membranes: Correlation with a three-dimensional model
15. FhuA, a transporter of the Escherichia coli outer membrane, is converted into a channel upon binding of phage T5
16. Crystal structure of the outer membrane active transporter FepA from Escherichia coli
17. β-Barrel proteins from bacterial outer membranes: Structure, function and refolding
18. Plasticity of Escherichia coli porin channels
19. Biochemical and biophysical characterization of OmpG: A monomeric porin
20. Crystal structures explain functional properties of two E. coli porins
21. The selectivity filter of voltage-dependent channels formed by phosphoporin (PhoE) from E. coli
22. Selectivity for maltose and maltodextrins of maltoporin, a pore-forming protein of E. coli outer membrane
23. Cadaverine induces closing of E. coli porins
24. Polyamines decrease Escherichia coli outer membrane permeability
25. Membrane-derived oligosaccharides (MDOs) promote closing of an E. coli porin channel
26. Function and modulation of porins: Insights from electrophysiology
27. Exotoxins of Staphylococcus aureus
28. Extended sugar slide function for the periplasmic coiled coil domain of ScrY
29. Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway
30. Crystal structure and functional characterization of OmpK36, the osmoporin of Klebsiella pneumoniae
31. Role of the constriction loop in the gating of outer membrane porin PhoE of Escherichia coli
32. Biochemistry and regulation of a novel Escherichia coli K-12 porin protein, OmpG, which produces unusually large channels
33. Site-directed spin labeling of membrane proteins and peptide-membrane interactions
34. Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide
35. Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose
36. Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters
37. Plasmid-mediated sucrose metabolism in Escherichia coli: Characterization of scrY, the structural gene for a phosphoenolpyruvate-dependent sucrose phosphotransferase system outer membrane porin
38. Complex inhibition of OmpF and OmpF bacterial porins by polyamines
39. Molecular basis for the polyamine - OmpF porin interactions: Inhibitor and mutant studies
40. Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria
41. Electrostatic properties of two porin channels from Escherichia coli
42. Genetically engineered metal ion binding sites on the outside of a channel's transmembrane beta-barrel
43. Conversion of the FhuA transport protein into a diffusion channel through the outer membrane of Escherichia coli
44. Structure and function of bacterial outer membrane proteins: Barrels in a nutshell
45. Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
46. Structure of the membrane channel porin from Rhodopseudomonas blastica at 2.0 Å resolution
47. OmpC mutants which allow growth on maltodextrins show increased channel size and greater voltage sensitivity
48. Porins of Escherichia coli: Unidirectional gating by pressure
49. Disruption of polyamine modulation by a single amino acid substitution on the L3 loop of the OmpC porin channel
50. The spontaneous gating activity of OmpC porin is affected by mutations of a putative hydrogen bond network or of a salt bridge between the L3 loop and the barrel
51. Inhibitory effect of acidic pH on OmpC porin: Wildtype and mutant studies
52. Regulation of porin-mediated outer membrane permeability by nutrient limitation in Escherichia coli
53. Effects of pore mutations and permeant ion concentration on the spontaneous gating activity of OmpC porin
54. Global adaptations resulting from high population densities in Escherichia coli cultures
55. Transmembrane signaling across the ligand-gated FhuA receptor: Crystal structures of free and ferrichrome-bound states reveal allosteric changes
56. Heptameric structures of two α-hemolysin mutants imaged with in situ atomic force microscopy
57. Ionic channels formed by Staphylococcus aureus alpha-toxin: Voltage-dependent inhibition by divalent and trivalent cations
58. A novel mutation, cog, which results in production of a new porin protein (OmpG) of Escherichia coli K-12
59. TonB-dependent iron acquisition: Mechanisms of siderophore-mediated active transport
60. Characterization of in vitro interactions between a truncated TonB protein from Escherichia coli and the outer membrane receptors FhuA and FepA
61. Voltage and pH-induced channel closure of porin OmpF visualized by atomic force microscopy
62. Outer membrane
63. Influence of pH on bacterial gene expression
64. Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel
65. Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states
66. Structure of the outer membrane protein A transmembrane domain
67. Voltage gating of Escherichia coli porin channels: Role of the constriction loop
68. Stability of trimeric OmpF porin: The contribution of the latching loop L2
69. From acids to osmZ-multiple factors influence synthesis of the OmpF and OmpC porins in Escherichia coli
70. Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form
71. Aerolysin - A paradigm for membrane insertion of beta-sheet protein toxins?
72. Ionophore properties of OmpA of Escherichia coli
73. Structural and functional characterization of OmpF porin mutants selected for larger pore size
74. Replacement of the sole histidinyl residue in OmpF porin from E. coli by threonine (H21T) does not affect channel structure and function
75. Ion channel formation by N-terminal domain: A common feature of OprF's of Pseudomonas and OmpA or Escherichia coli
76. E. coli PhoE porin has an opposite voltage-dependence from the homologous OmpF
77. Distinct sensitivities of OmpF and PhoE to charged modulators
78. Excretion of endogenous cadaverine leads to a decrease in porin-mediated outer membrane permeability
79. Expression of outer membrane proteins in Escherichia coli growing at acid pH
80. Matrix protein from Escherichia coli outer membranes forms voltage-controlled channels in lipid bilayers
81. Structural basis for sugar translocation through maltoporin channels at 3.1 Å resolution
82. General and specific porins from bacterial outer membranes
83. β-Barrel membrane proteins
84. Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore
85. OmpA protein of Escherichia coli outer membrane occurs in open and closed channel forms
86. Substrate-induced assembly of a contiguous channel for protein export from E. coli: Reversible bridging of an inner-membrane translocase to an outer membrane exit pore
87. Effects of pH on bacterial porin function
88. Site-directed mutagenesis of loop L3 of sucrose porin ScrY leads to changes in substrate selectivity
89. Transmembrane β-barrel of staphylococcal α-toxin forms in sensitive but not in resistant cells
90. Staphylococcal alpha-toxin: Repair of a calcium-impermeable pore in the target cell membrane
91. Plasticity of the transmembrane β-barrel
92. Voltage sensing in the PhoE and OmpF outer membrane porins of Escherichia coli: Role of charged residues
93. Oriented channels reveal asymmetric energy barrier for sugar translocation through maltoporin of Escherichia coli
94. The structure of porin from Rhodobacter capsulatus at 1.8 Å resolution
95. Insertion mutagenesis and membrane topology model of the Pseudomonas aeruginosa outer membrane protein OprM
96. Crystal structure of Omp32, the anion-selective porin from Comamonas acidovorans, in complex with a periplasmic peptide at 2.1 Å resolution
97. Bypassing the periplasm: Reconstitution of the AcrAB multidrug efflux pump of Escherichia coli
98. Multidrug resistance mechanisms: Drug efflux across two membranes