TonB-dependent iron acquisition: Mechanisms of siderophore-mediated active transport

Molecular Microbiology

Volumn 28, Issue 4, 1998, Pages 675-681

  Moeck, Gregory S ^a,b   Coulton, James W ^a  

^a MCGILL UNIVERSITY   (Canada)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CYTOPLASM PROTEIN; IRON; IRON CHELATE; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; PORIN; SIDEROPHORE;

ACTIVE TRANSPORT; BACTERIAL OUTER MEMBRANE; GRAM NEGATIVE BACTERIUM; IRON TRANSPORT; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTON MOTIVE FORCE; RECEPTOR AFFINITY; SHORT SURVEY; SIGNAL TRANSDUCTION;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; IRON; LIGANDS; MEMBRANE PROTEINS; RECEPTORS, CELL SURFACE; SIDEROPHORES; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 0031803840     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00817.x     Document Type: Short Survey

References (32)

1. Bonhivers, M., Ghazi, A., Boulanger, P., and Letellier, L. (1996) FhuA, a transporter of the Escherichia coli outer membrane, is converted into a channel upon binding of bacteriophage T5. EMBO J15: 1850-1856.
2. Boulanger, P., le Maire, M., Bonhivers, M., Dubois, S., Desmadril, M., and Letellier, L. (1996) Purification and structural and functional characterization of FhuA, a transporter of the Escherichia coli outer membrane. Biochemistry 35: 14216-14224.
3. Braun, V. (1997) Avoidance of iron toxicity through regulation of bacterial iron transport. Biol Chem 378: 779-786.
4. Ghosh, A., Ghosh, M., Niu, C., Malouin, F., Moellmann, U., and Miller, MJ. (1996) Iron transport-mediated drug delivery using mixed-ligand siderophore-β-lactam conjugates. Chem Biol 3: 1011-1019.
5. Guerinot, M.L. (1994) Microbial iron transport. Annu Rev Microbiol 48: 743-772.
6. Jiang, X., Payne, M.A., Cao, Z., Foster, S.B., Feix, J.B., Newton, S.M.C., et al. (1997) Ligand-specific opening of a gated porin channel in the outer membrane of living bacteria. Science 276: 1261-1264.
7. Iwata, S., Ostermeier, C., Ludwig, B., and Michel, H. (1995) Structure at 2.8 A resolution of cytochrome c oxidase from Paracoccus denitrificans. Nature 376: 660-669.
8. 12 transport in Escherichia coli: energy coupling between membranes. Mol Microbiol 4: 2027-2033.
9. Kadner, R.J., and Heller, K.J. (1995) Mutual inhibition of cobalamin and siderophore uptake systems suggests their competition for TonB function. J Bacteriol 177: 4829-4835.
10. Killmann, H., Benz, R., and Braun, V. (1993) Conversion of the FhuA transport protein into a diffusion channel through the outer membrane of Escherichia coli. EMBO J 12: 3007-3016.
11. Killmann, H., Videnov, G., Jung, G., Schwarz, H., and Braun, V. (1995) Identification of receptor binding sites by competitive peptide mapping: phages T1, T5, and phi 80 and colicin M bind to the gating loop of FhuA. J Bacteriol 177: 694-698.
12. Killmann, H., Benz, R., and Braun, V. (1996) Properties of the FhuA channel in the Escherichia coli outer membrane after deletion of FhuA portions within and outside the predicted gating loop. J Bacteriol 178: 6913-6920.
13. Klebba, P.E., Rutz, J.M., Liu, J., and Murphy, O.K. (1993) Mechanisms of TonB-catalyzed iron transport through the enteric bacterial cell envelope. J Bioenerg Biomemb 25: 603-611.
14. v fragments as a tool for the one-step purification of integral multisubunit membrane protein complexes. BioTechnology 13: 155-160.
15. Koebnik, R., and Braun, V. (1993) Insertion derivatives containing segments of up to 16 amino acids identify surfaceand periplasm-exposed regions of the FhuA outer membrane receptor of Escherichia coil K-12. J Bacteriol 175: 826-839.
16. Larsen, R.A., Myers, P.S., Skare, J.T., Seachord, C.L., Darveau, R.P., and Postle, K. (1996) Identification of TonB homologs in the family Enterobacteriaceae and evidence for conservation of TonB-dependent energy transduction complexes. J Bacteriol 178: 1363-1373.
17. Larsen, R.A., Foster-Hartnett, D., McIntosh, M.A., and Postle, K. (1997) Regions of Escherichia coli TonB and FepA proteins essential for in vivo physical interactions. J Bacteriol 179: 3213-3221.
18. Lathrop, J.T., Wei, B.-Y., Tochie, G.A., and Kadner, R.J. (1995) Sequences of the Escherichia coli BtuB protein essential for its insertion and function in the outer membrane. J Bacteriol 177: 6810-6819.
19. Letain, T.E., and Postle, K. (1997) TonB protein appears to transduce energy by shuttling between the cytoplasmic membrane and the outer membrane in Escherichia coli. Mol Microbiol 24: 271-283.
20. Letellier, L., Locher, K.P., Plançon, L., and Rosenbusch, J.P. (1997) Modeling ligand-gated receptor activity. FhuA-mediated ferrichrome efflux from lipid vesicles triggered by phage T5. J Biol Chem 272: 1448-1451, 8836.
21. Liu, J., Rutz, J.M., Feix, J.B., and Klebba, P.E. (1993) Permeability properties of a large gated channel within the ferric enterobactin receptor, FepA. Proc Natl Acad Sci USA 9O: 10653-10657.
22. Liu, J., Rutz, J.M., Klebba, P.E., and Feix, J.B. (1994) Ligand-induced conformational change in the ferric enterobactin receptor, FepA: a spin labeling study. Biochemistry 33: 13274-13283.
23. Moeck, G.S., Ratcliffe, M.J.H., and Coulton, J.W. (1995) Topological analysis of the Escherichia coli ferrichrome-iron receptor by using monoclonal antibodies. J Bacteriol 177: 6118-6125.
24. Moeck, G.S., Tawa, P., Xiang, H., Ismail, A.A., Turnbull, J.L., and Coulton, J.W. (1996) Ligand-induced conformational change in the ferrichrome-iron receptor of Escherichia coli K-12. Mol Microbiol 22: 459-471.
25. Moeck, G.S., Postle, K., and Coulton, J.W. (1997) Cell envelope signalling in Escherichia coli. Ligand binding to the ferrichrome-iron receptor FhuA promotes interaction with the energy-transducing protein TonB. J Biol Chem 272: 28391-28397.
26. Newton, S.M.C., Allen, J.S., Cao, Z., Qi, Z., Jiang, X., Sprencel, C., et al. (1997) Double mutagenesis of a positive charge cluster in the ligand-binding site of the ferric enterobactin receptor, FepA. Proc Natl Acad Sci USA 94: 4560-4565.
27. Plançon, L., Chami, M., and Letellier, L. (1997) Reconstitution of FhuA, an Escherichia coli outer membrane protein, into liposomes. Binding of phage T5 to FhuA triggers the transfer of DNA into the proteoliposomes. J Biol Chem 272: 16868-16872.
28. Postle, K. (1993) TonB protein and energy transduction between membranes. J Bioenerg Biomemb 25: 591-601.
29. 12 in Escherichia coli. Some observations on the roles of the gene products of btuC and tonB. J Biol Chem 255: 4313-4319.
30. Rutz, J.M., Liu, J., Lyons, J.A., Goranson, J., Armstrong, S.K., McIntosh, M.A., et al. (1992) Formation of a gated channel by a ligand-specific transport protein in the bacterial outer membrane. Science 258: 471-475.
31. Skare, J.T., Ahmer, B.M.M., Seachord, C.L, Darveau, R.P., and Postle, K. (1993) Energy transduction between membranes. TonB, a cytoplasmic membrane protein, can be chemically cross-linked in vivo to the outer membrane receptor FepA. J Biol Chem 268: 16302-16308.
32. Stojiljkovic, I., and Srinavasan, N. (1997) Neisseria meningitidis tonB, exbB, and exbD genes: Ton-dependent utilization of protein-bound iron in Neisseriae. J Bacteriol 179: 805-812.