SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 1, 2002, Pages 71-77

Synthesis of novel paclitaxel prodrugs designed for bioreductive activation in hypoxic tumour tissue

(5) Damen, Eric W P a Nevalainen, Tapio J b Van den Bergh, Toine J M a De Groot, Franciscus M H a Scheeren, Hans W a

a RADBOUD UNIVERSITY NIJMEGEN (Netherlands)

b UNIVERSITY OF EASTERN FINLAND (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

PACLITAXEL; PRODRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ACTIVATION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYPOXEMIA; REDUCTION;

ANTINEOPLASTIC AGENTS; CELL DIVISION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION-REDUCTION; PACLITAXEL; PRODRUGS; SPECTRUM ANALYSIS; TUMOR CELLS, CULTURED;

EID: 0036131908 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(01)00235-8 Document Type: Article

Times cited : (66)

References (30)

1
- 0033405294
- (1999) Cancer Res. , vol.59 , pp. 5863
- Brown, J.M.¹

2
- 0034176782
- (2000) Mol. Med. Today , vol.6 , pp. 157
- Brown, J.M.¹

3
- 0006695378
- Denny, W.A. In Cancer Chemotherapeutic Agents; Foye, W.O. Ed., Am. Chem. Soc.: Washington DC, 1995; p 483.

4
- 0031306972
- (1997) Oncol. Res. , vol.9 , pp. 357
- Siim, B.G.¹ Denny, W.A.² Wilson, W.R.³

5
- 0034695519
- (2000) Tetrahedron , vol.56 , pp. 645
- Hay, M.P.¹ Wilson, W.² Denny, W.A.³

6
- 0027288316
- (1993) Br. J. Cancer , vol.67 , pp. 1163
- Brown, J.M.¹

7
- 0033545676
- (1999) J. Med. Chem. , vol.42 , pp. 941
- Shyam, K.¹ Penketh, P.G.² Shapiro, M.³ Belcourt, M.F.⁴ Loomis, R.H.⁵ Rockwell, S.⁶ Sartorelli, A.C.⁷

8
- 0027738619
- (1993) Bioorg. Med. Chem. Lett. , vol.3 , pp. 2471
- Kant, J.¹ Huang, S.² Wong, H.³ Fairchild, C.⁴ Vyas, D.⁵ Farina, V.⁶

9
- 0019453510
- For mechanistic details, see:
- (1981) J. Med. Chem. , vol.24 , pp. 479
- Carl, P.L.¹ Chakravarty, P.K.² Katzenellenbogen, J.A.³

10
- 0000231181
- (1983) New J. Chem. , vol.7 , pp. 439
- Wakselman, M.¹

11
- 0343337640
- For recent reviews about the prodrug concept, see:
- (1996) Adv. Drug Delivery Rev. , vol.19 , pp. 241
- Sinhababa, D.K.¹ Thakker, D.R.²

12
- 0033180164
- (1999) Pharmacol. Ther. , vol.83 , pp. 67
- Dubowchik, G.M.¹ Walker, M.A.²

13
- 0034941481
- (2001) Curr. Med. Chem. , vol.18 , pp. 1093
- De Groot, F.M.H.¹ Damen, E.W.P.² Scheeren, H.W.³

14
- 0025773708
- (1991) Xenobiotica , vol.21 , pp. 935
- Nicholls, D.¹ Gescher, A.² Griffin, R.J.³

15
- 0002934074
- Although reduction by endogenous thiols may hamper the application of azides in hypoxia selective prodrugs.
- (1996) J. Chem. Soc., Perkin Trans 1 , pp. 1205
- Griffin, R.J.¹ Evers, E.² Davidson, R.³ Gibson, A.E.⁴ Layton, D.⁵ Irwin, W.J.⁶

16
- 0006681293
- Commercially available or prepared according to literature procedures: see ref 10.
- (1985) J. Chem. Res. Miniprint , vol.5 , pp. 1814
- Beadle, C.D.¹ Bowman, W.R.²

17
- 0027406010
- (1993) Tetrahedron Lett. , vol.34 , pp. 1747
- Rao, V.P.¹ Jen, A.K.² Wong, K.Y.³ Drost, K.J.⁴

18
- 0032396955
- (1998) Chem. Lett , pp. 3
- Shiina, I.¹ Saitoh, K.² Fréchard-Ortuno, I.³ Mukaiyama, T.⁴

19
- 0032514504
- (1998) Tetrahedron Lett. , vol.39 , pp. 6081
- Damen, E.W.P.¹ Braamer, L.² Scheeren, J.W.³

20
- 0001781416
- (1986) J. Org. Chem. , vol.51 , pp. 46
- Denis, J.N.¹ Greene, A.E.² Serra, A.A.³ Luche, M.J.⁴

21
- 0000633977
- (1994) Tetrahedron Lett. , vol.35 , pp. 4486
- Kingston, D.G.I.¹ Chaudhary, A.G.² Gunatilaka, A.A.L.³ Middleton, M.L.⁴

22
- 0034632849
- The preparation of 2′-carbamate prodrugs of paclitaxel with an additional ring-closure spacer may lead to more stable prodrugs, see:
- (2000) J. Med. Chem. , vol.43 , pp. 3093
- De Groot, F.M.H.¹ Van Berkom, L.W.A.² Scheeren, J.W.³

23
- 0028058771
- (1994) J. Org. Chem. , vol.59 , pp. 5104
- Wang, Z.¹ Kolb, H.C.² Sharpless, K.B.³

24
- 0006650548
- (1985) Synthesis , pp. 653
- Sur, B.¹ Adak, M.M.² Pathak, T.³ Hazra, B.⁴ Banerjec, A.⁵

25
- 0024409225
- (1989) Chem. Pharm. Bull. , vol.37 , pp. 1904
- Mori, M.¹ Kawajiri, T.² Sayama, M.³ Miyahara, T.⁴ Kozuka, H.⁵

26
- 0001460085
- (1996) J. Org. Chem. , vol.61 , pp. 1155
- Showalter, H.D.H.¹ Sun, L.² Sercel, A.D.³ Winters, R.T.⁴ Denny, W.A.⁵ Palmer, B.D.⁶

27
- 37049085499
- (1987) J. Chem. Soc. Perkin Trans 1 , pp. 2819
- Adebayo, A.T.O.M.¹ Russel, B.W.² Salt, W.G.³

28
- 33749093333
- (1997) J. Chem. Soc. Perkin Trans 1 , pp. 1147
- Berry, J.M.¹ Watson, C.Y.² Threadgill, M.D.³

29
- 0027406010
- (1993) Tetrahedron Lett. , vol.34 , pp. 1747
- Rao, V.P.¹ Jen, A.K.² Wong, K.Y.³ Drost, K.J.⁴

30
- 0025878872
- (1991) Eur. J. Cancer , vol.27 , pp. 897
- Kepers, Y.P.¹ Peters, G.J.² Van Ark-Otte, J.³ Winograd, B.⁴ Pinedo, H.M.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.