Immunopathology and immunoprotection in CNS virus infections: Mechanisms of virus clearance from the CNS

Current Topics in Microbiology and Immunology

Volumn 265, Issue , 2002, Pages 163-182

  Hooper, D C ^a   Sauder, C ^b   Scott, G S ^a   Dietzschold, B ^a   Richt, J A ^c,d  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

^d National Animal Oisease Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CHEMOKINE; CYTOKINE; FREE RADICAL; INTERFERON; TUMOR NECROSIS FACTOR ALPHA;

BLOOD BRAIN BARRIER; BORNA DISEASE VIRUS; BRAIN INFECTION; CELL LINEAGE; CELLULAR IMMUNITY; CLEARANCE; CYTOLYSIS; EFFECTOR CELL; HUMAN; HUMORAL IMMUNITY; IMMUNITY; IMMUNOPATHOLOGY; MONOCYTE; NEUROTROPISM; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RABIES VIRUS; REVIEW; T LYMPHOCYTE; VIRUS INFECTION; VIRUS PATHOGENESIS; VIRUS REPLICATION;

ANIMALS; ANTIBODY FORMATION; BORNA DISEASE VIRUS; CENTRAL NERVOUS SYSTEM VIRAL DISEASES; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY, CELLULAR; RABIES VIRUS; VIRAL PHYSIOLOGY;

BORNA DISEASE VIRUS; RABIES VIRUS;

EID: 0036131252     PISSN: 0070217X     EISSN: None     Source Type: Journal    
DOI: 10.1007/978-3-662-09525-6_8     Document Type: Review

References (83)

1. Chemokine gene expression in the brains of mice with lymphocytic choriomeningitis
2. The double-edged role of nitric oxide in brain function and superoxide-mediated injury
3. Cellular responses to interferon-γ
4. Differential chemokine induction by the mouse adenovirus type-1 in the central nervous system of susceptible and resistant strains of mice
5. Interferon-inducible T cell α chemoattractant (I-TAC): A novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3
6. Rabies virus glycoprotein. Biological and serological characterization
7. --mediated oxidations
8. Determination of immune cells and expression of major histocompatibility complex class II antigen in encephalitic lesions of experimental Borna disease
9. Antiviral activity of α-interferon in Sindbis virus-infected cells is restored by anti-E2 monoclonal antibody treatment
10. The blood-brain barrier in neuroinflammatory diseases
11. Antibody-mediated clearance of viruses from the mammalian central nervous system
12. The role of nitric oxide in physiology and pathophysiology
13. Mechanisms of rabies virus neutralization by glycoprotein-specific monoclonal antibodies
14. Delineation of putative mechanisms involved in antibody-mediated clearance of rabies virus from the CNS
15. Expression of Clq, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis
16. Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is up-regulated following cerebral hypoxic-ischemic injury to the developing rat brain
17. Theiler's virus infection of 129Sv mice that lack the interferon α/β or interferon γ receptors
18. Gamma interferon is a major mediator of antiviral defense in experimental measles virus-induced encephalitis
19. Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-γ over IL-4 responses
20. Interferons: Cell signalling, immune modulation, antiviral response and virus countermeasures
21. Cytokine-induced viral purging-role in viral pathogenesis
22. Noncytolytic control of viral infections by the innate and adaptive immune response
23. Suppression of rat cytomegalovirus replication by antibodies against interferon-γ
24. Inhibition of Borna disease virus multiplication by interferon: Cell line differences in susceptibility
25. Mx proteins: Mediators of innate resistance to RNA viruses
26. Evolution of the immune response in the central nervous system following infection with Borna disease virus
27. Perform is not essential for development of T cell-mediated neurological disease after Borna disease virus infection of susceptible mice
28. Local nitric oxide production in viral and autoimmune diseases of the central nervous system
29. Collaboration of antibody and inflammation in the clearance of rabies virus from the CNS
30. Uric acid, a peroxynitrite-scavenger, inhibits CNS inflammation, blood-CNS barrier permeability changes, and tissue damage in a mouse model of multiple sclerosis
31. The CNS inflammatory response to neurotropic virus infection is peroxynitrite-dependent
32. Regulation of human immunodeficiency virus type 1 replication in human T lymphocytes by nitric oxide
33. Role of peroxynitrite as a mediator of pathophysiological alterations in experimental pneumococcal meningitis
34. The peroxynitrite scavenger uric acid prevents inflammatory cell invasion into the CNS in experimental allergic encephalomyelitis through maintenance of blood-CNS barrier integrity
35. Role of chemokines in the regulation of Th1/Th2 and autoimmune encephalomyelitis
36. IFN-γ is not required in the IL-12 response to vesicular stomatitis virus infection of the olfactory bulb
37. T cell-dependent IFN-γ exerts an antiviral effect in the central nervous system but not in peripheral solid organs
38. Dynamic regulation of α- and β-chemokine expression in the central nervous system during mouse hepatitis virus-induced demyelinating disease
39. Disassociation between the in vitro and in vivo effects of nitric oxide on a neurotropic murine coronavirus
40. Complement depletion does not reduce brain injury in a rabbit model of thromboembolic stroke
41. Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis
42. Neuroprotective versus neurodestructive effects of NO-related species
43. Chemokine receptor specific for IP10 and mig: Structure, function, and expression in activated T-lymphocytes
44. C-C chemokines differentially alter interleukin-4 production from lymphocytes
45. MHV infection of the CNS: Mechanisms of immune-mediated control
46. Immunobiology of the blood-brain barrier
47. Cytokines: Interferon-γ
48. Virus-specific CD4+ T cells eliminate Borna disease virus from the brain via induction of cytotoxic CD8 + T cells
49. Vaccination for disease
50. Induction of protection against Borna disease by inoculation with high-dose-attenuated Borna disease virus
51. IFN-γ is required for viral clearance from central nervous system oligodendroglia
52. Cytokine induction during T-cell-mediated clearance of mouse hepatitis virus from neurons in vivo
53. Lysis of major histocompatibility complex class-bearing cells in Borna disease virus-induced degenerative encephalopathy
54. A case for cytokines as effector molecules in the resolution of virus infection
55. Does nitric oxide play a critical role in viral infections?
56. Influence of interferon on persistent infection caused by Borna disease virus
57. Borna disease virus infected astrocytes function in vitro as antigen-presenting and target cells for virus-specific CD4-bearing lymphocytes
58. Borna disease, a progressive encephalomyelitis as a model for CD4+ T cell-mediated immunopathology in the brain
59. Borna disease virus-induced meningoencephalomyelitis caused by a virus-specific CD4+ T cell-mediated immune reaction
60. Borna disease virus-specific T cells protect against or cause immunopathological Borna disease
61. Upregulation of COX-2 and CGRP expression in resident cells of the Borna Disease virus-infected brain is dependent upon inflammation
62. In vivo protective effect of tumour necrosis factor α against experimental infection with herpes simplex virus type 1
63. Natural and experimental Borna disease
64. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
65. Chemokine gene expression in astrocytes of Borna disease virus-infected rats and mice in the absence of inflammation
66. Immune surveillance and autoantigen recognition in the central nervous system
67. Recombinant interferon-γ applied to the brain ventricular system protects rats against pseudorabies
68. Tumour necrosis factor-α, interferon-γ and interferon-β exert antiviral activity in nervous tissue cells
69. Use of mouse anti-rabies monoclonal antibodies in postexposure treatment of rabies
70. Kinetics of virus spread and changes in levels of several cytokine mRNAs in the brain after intranasal infection of rats with Borna disease virus
71. The role of γ interferon in infection of susceptible mice with murine coronavirus MHV-JHM
72. Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the CNS by the natural peroxynitrite scavenger uric acid
73. Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid
74. σ/β Interferon promotes transcription and inhibits replication of Borna disease virus in persistently infected cells
75. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells
76. Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro
77. An essential role for type 1 interferon-γ in terminating persistent viral infection
78. Inhibition of nitric oxide synthesis increases mortality in Sindbis virus encephalitis
79. - oxidations by carbon dioxide
80. Interferons and other cytokines
81. The murine chemokine CXCL11(IFN-inducible T cell α chemoattractant) is an IFN-γ- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia
82. Identification of a population of CD4+ CTL that utilizes perforinrather than a Fas ligand-dependent cytotoxic mechanism
83. Severity of neurological signs and degree of inflammatory lesions in the brains of rats with Borna disease correlate with the induction of nitric oxide synthase