Protection of myelin basic protein immunized mice from free-radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid

Neuroscience Letters

Volumn 292, Issue 2, 2000, Pages 137-141

  Spitsin, Sergei V ^a   Scott, Gwen S ^a   Kean, Rhonda B ^a   Mikheeva, Tatiana ^a   Hooper, D Craig ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Autoimmunity; Blood brain barrier; Demyelinating diseases; Encephalomyelitis; Multiple sclerosis; Nitric oxide; Peroxynitrite; Uric acid

Indexed keywords

MYELIN BASIC PROTEIN; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; URIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DEMYELINATION; ENCEPHALOMYELITIS; INFLAMMATION; MONOCYTE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; BLOOD-BRAIN BARRIER; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FREE RADICALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMMUNIZATION; LIPID PEROXIDATION; MICE; MICE, INBRED STRAINS; MONOCYTES; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; NITRATES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; URIC ACID;

EID: 0034613447     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01446-4     Document Type: Article

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