Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor

Blood

Volumn 99, Issue 1, 2002, Pages 372-374

  Kratz, Christian P ^c   Emerling, Brooke M ^c   Bonifas, Jeannette ^c   Wang, Winfred ^c   Green, Eric D ^c   Le Beau, Michelle M ^c   Shannon, Kevin M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PHOSPHATIDYLINOSITOL 3 KINASE;

ALLELE; ARTICLE; CHROMOSOME 7Q; CHROMOSOME DELETION; COLON CANCER; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MISSENSE MUTATION; MONOSOMY 7; MYELOID LEUKEMIA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; TELOMERE; TUMOR SUPPRESSOR GENE;

EID: 0036090377     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.1.372     Document Type: Article

References (27)

1. Structural insights into phosphoinositide 3-kinase catalysis and signalling
2. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
3. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation
4. Roles of PLC-beta2 and -beta3 and P13Kgamma in chemoattractant-mediated signal transduction
5. Function of P13Kgamma in thymocyte development, T cell activation, and neutrophil migration
6. Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma
7. Nonrandom chromosomal abnormalities in acute nonlymphocytic leukemia in patients treated for Hodgkin disease and non-Hodgkin lymphoma
8. Childhood monosomy 7: Epidemiology, biology and mechanistic implications
9. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
10. Tumor suppressor genes
11. Cytogenetic and molecular deliniation of the region of chromosome 7 commonly deleted in malignant myeloid disorders
12. Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies
13. Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias
14. Chromosome 7 long-arm deletions in myeloid disorders: Terminal DNA sequences are commonly conserved and breakpoints vary
15. Molecular anatomy of chromosome 7q deletions in myeloid leukemia: Evidence for multiple critical loci
16. Delineation of multiple deleted regions in 7q in myeloid disorders
17. ras
18. Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
19. Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia
20. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
21. Aberrant methylation of gene promoters in cancer: Concepts, misconcepts, and promise
22. Developmental defects and tumor predisposition in Rb mutant mice
23. Tumor spectrum analysis in p53-mutant mice
24. Haplo-insufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
25. A new angle on a pervasive oncogene
26. The murine gene p27Kip1 is haplo-insufficient for tumour suppression
27. Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation