Cooperative regulation of CYP3A5 gene transcription by NF-Y and Sp family members

Biochemical and Biophysical Research Communications

Volumn 286, Issue 1, 2001, Pages 55-60

  Iwano, Shunsuke ^a   Saito, Tetsuya ^a   Takahashi, Yoshiki ^a   Fujita, Ken ichi ^a   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

BTE; Cap site hunting method; CCAAT box; cis acting element; Gel shift assay; Luciferase assay; Transcriptional initiation site

Indexed keywords

CIS ACTING ELEMENT; CYTOCHROME P450 3A5; CYTOCHROME P450 ISOENZYME; LUCIFERASE; NUCLEAR FACTOR; NUCLEAR FACTOR Y; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME SYNTHESIS; GENE CONTROL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION;

EID: 0034809534     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5352     Document Type: Article

References (25)

1. P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
2. The role of individual human cytochromes P450 in drug metabolism and clinical response
3. Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver
4. Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver
5. Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase
6. Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver
7. Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver, cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
8. P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate
9. Isolation of a new human fetal liver cytochrome P450 cDNA clone: Evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers
10. cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450
11. Genomic organization of the human CYP3A locus: Identification of a new, inducible CYP3A gene
12. Identification of glucocorticoic-inducible cytochromes P-450 in the intestinal mucosa of rats and man
13. Expression of cytochrome P450 3A in amphibian, rat, and human kidney
14. Detection of human lung cytochromes P450 that are immunechemically related to cytochrome IIE1 and cytochrome IIIA
15. Selective expression of CYP3A5 and not CYP3A4 in human blood
16. Sequence of the 5′-flanking region of CYP3A5: Comparative analysis with CYP3A4 and CYP3A7
17. Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells
18. A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions
19. Introducing cloned genes into cultured mammalian cells
20. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
21. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family
22. Nuclear factor I (NF I) binds to an NF I-type site but not to the CCAAT site in the human alpha-globin gene promoter
23. Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box
24. Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y
25. Sp1 and NF-Y are necessary and sufficient for growth-dependent regulation of the hamster thymidine kinase promoter