Regulation by calcium of the nitric oxide/cyclic GMP system in cerebellar granule cells and astroglia in culture

Journal of Neuroscience Research

Volumn 49, Issue 3, 1997, Pages 333-341

  Baltrons, Maria Antonia ^a   Saadoun, Samira ^a   Agulló, Luis ^a   García, Agustina ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Astroglia; Cyclic GMP phosphodiesterase; Granule neurons; Guanylyl cyclase; Nitric oxide

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCIMYCIN; CALCIUM ION; CALMODULIN INHIBITOR; CYCLIC GMP; ISOBUTYLMETHYLXANTHINE; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; N METHYL DEXTRO ASPARTIC ACID; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE (CALCIUM,CALMODULIN); UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; ENZYME ACTIVATION; GRANULE CELL; INTRACELLULAR TRANSPORT; MACROGLIA; MEMBRANE DEPOLARIZATION; NONHUMAN; PRIORITY JOURNAL; RAT;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; ASTROCYTES; CALCIUM; CELLS, CULTURED; CEREBELLUM; CYCLIC GMP; ENZYME INHIBITORS; GUANYLATE CYCLASE; MALE; N-METHYLASPARTATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; VASODILATOR AGENTS;

EID: 0030860554     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19970801)49:3<333::AID-JNR8>3.0.CO;2-D     Document Type: Article

References (30)

1. Agulló L, García A (1992): Characterization of noradrenaline-stimulated cyclic GMP formation in brain astrocytes in culture. Biochem J 288:619-624.
2. 2+/calmodulin-dependent cyclic GMP phosphodiesterase activity in granule neurons and astrocytes from cerebellum. Eur J Pharmacol (in press).
3. Agulló; L, Baltrons MA, García A (1995): Calcium-dependent nitric oxide formation in glial cells. Brain Res 686:160-168.
4. Arbonés ML, Ribera J, Agulló L, Baltrons MA, Casanovas A, Riveros-Moreno V, García A (1996): Characteristics of nitric oxide synthase type I of rat cerebellar astrocytes. Glia 18:224-232.
5. Bredt DS, Snyder SH (1990): Isolation of nitric oxide synthetase, a calmodulin requiring enzyme. Proc Natl Acad Sci USA 87:682-685.
6. Bredt DS, Hwang PM, Snyder SH (1990): Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 347:768-770.
7. Bredt DS, Glatt CE, Hwang PM, Fotuhi M, Dawson TM, Snyder SH (1991): Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron 7:615-624.
8. Brenman JE, Chao DS, Gee SH, Mcgee AW, Craven SE, Santillano DR, Wu ZQ, Huang F, Xia HH, Peters MF, Froehner SC, Bredt DS (1996): Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha 1-syntrophin mediated by PDZ domains. Cell 84:757-767.
9. De Vente J, Bol JGJM, Steinbusch HWM (1989): cGMP-producing, atrial natriuretic factor-responding cells in the rat brain. Eur J Neurosci 1:436-460.
10. De Vente J, Bol JGJM, Berkelmans HS, Schipper J, Steinbusch HMW (1990): Immunocytochemistry of cGMP in the cerebellum of the immature, adult, and aged rat: The involvement of nitric oxide. A micropharmacological study. Eur J Neurosci 2:845-862.
11. Garthwaite J, Boulton CL (1995): Nitric oxide signaling in the central nervous system. Annu Rev Physiol 57:683-706.
12. Garthwaite J, Garthwaite G (1987): Cellular origins of cyclic GMP B responses to excitatory amino acid receptor agonists in rat cerebellum in vitro. J Neurochem 48:29-39.
13. Garthwaite J, Charles SL, Chess-Williams R (1988): Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intracellular messenger in the brain. Nature 336:385-388.
14. Kiedrowski L, Costa E, Wroblewski TJ (1992): Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells. J Neurochem 58:335-341.
15. Kiedrowski L, Costa E, Wroblewski JT (1994): Sodium nitroprusside inhibits N-methyl-D-aspartate-evoked calcium influx via a nitric oxide- and cGMP-independent mechanism. Mol Pharmacol 41:779-784.
16. Knowles RG, Palacios M, Palmer MJ, Moncada S (1989): Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of the soluble guanylate cyclase. Proc Natl Acad Sci USA 86:5159-5162.
17. Kugler P, Drenckhahn D (1996): Astrocytes and Bergmann glia as an important site of nitric oxide synthase I. Glia 16:165-173.
18. Levi G, Aloisi F, Ciotti MT, Thangnipon W, Kingsbury A, Balazs R (1989): Preparation of 98% pure cerebellar granule cell cultures. In Shahar A, de Vellis J, Vernadakis A, Haber B (eds): "A Dissection and Tissue Culture Manual of the Nervous System." New York: Alan R. Liss, pp 211-214.
19. Lowry OM, Roebrough NJ, Farr AL, Randall RJ (1951): Protein measurements with the Folin phenol reagent. J Biol Chem 193:265-275.
20. Malcom C, Grieve A, Ritchie L, Schousboe A, Griffiths R (1996): NMDA receptor-mediated cGMP synthesis in primary cultures of mouse cerebellar granule cells appears to involve neuronastrocyte communication with NO operating as the intercellular messenger. J Neurosci Res 45:129-142.
21. 2+. J Neurochem 59:2024-2029.
22. Murphy S, Simmons ML, Agulló L, García A, Feinstein DL, Galea E, Reis DJ, Minc-Golom D, Schwartz JP (1993): Synthesis of nitric oxide in CNS glial cells. Trends Neurosci 16:323-328.
23. Nakane M, Ichikawa M, Deguchi T (1983): Light and electron microscopic demonstration of guanylate cyclase in rat brain. Brain Res 273:9-15.
24. Novelli A, Nicoletti F, Wroblewski JT, Alho H, Costa E, Guidotti A (1987): Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells. J Neurosci 7:40-47.
25. Schmidt HHHW, Gagne GD, Nakane M, Pollock JS, Miller MF, Murad F (1992): Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction. J Histochem Cytochem 40:1439-1456.
26. Schmidt HHHW, Lohmann SM, Walter U (1993): The nitric oxide and cGMP signal transduction system: Regulation and mechanism of action. Biochim Biophys Acta 1178:153-175.
27. Southam E, Garthwaite J (1993): The nitric oxide-cyclic GMP signalling pathway in rat brain. Neuropharmacology 32:1267-1277.
28. Southam E, Morris R, Garthwaite J (1992): Sources and targets of nitric oxide in rat cerebellum. Neurosci Lett 137:241-244.
29. Van C, Zhao AZ, Bentley JK, Beavo JA (1996): The calmodulin-dependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner. J Biol Chem 271:25699-25706.
30. Zwiller J, Ghandour MS, Revel MO, Basset P (1981): Immunohistochemical localization of guanylate cyclase in rat cerebellum. Neurosi Lett 23:31-36.