Rolipram, a selective phosphodiesterase type-IV inhibitor, prevents induction of heat shock protein HSP-70 and hsp-70 mRNA in rat retrosplenial cortex by the NMDA receptor antagonist dizocilpine

European Journal of Neuroscience

Volumn 9, Issue 9, 1997, Pages 1891-1901

  Hashimoto, Kenji ^a,b,c   Tomitaka, Shin Ichiro ^a   Bi, Ying ^b   Narita, Natsuko ^a   Minabe, Yoshio ^a   Iyo, Masaomi ^b  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^c Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

Immediate early genes; Microglia activation; Neurotoxicity; Phencyclidine; Phosphodiesterase inhibitors

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; DIZOCILPINE; HEAT SHOCK PROTEIN 70; ISOBUTYLMETHYLXANTHINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE IV; ROLIPRAM;

ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; CELL VACUOLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HISTOPATHOLOGY; IMMEDIATE EARLY GENE; INTRAPERITONEAL DRUG ADMINISTRATION; MICROGLIA; NEUROTOXICITY; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT;

ANIMALS; BEHAVIOR, ANIMAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HSP70 HEAT-SHOCK PROTEINS; LIMBIC SYSTEM; MICROGLIA; NERVE TISSUE PROTEINS; PHOSPHODIESTERASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-FOS; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; ROLIPRAM;

EID: 0030981741     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb00756.x     Document Type: Article

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