Tumor necrosis factor-α increases sodium and chloride conductance across the tight junction of CACO-2 BBE, a human intestinal epithelial cell line

Journal of Membrane Biology

Volumn 161, Issue 3, 1998, Pages 263-274

  Marano, C W ^a   Lewis, S A ^b   Garulacan, L A ^a   Peralta Soler, A ^a   Mullin, J M ^a  

^a LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Cytokine; Epithelia; Intestine; Paracellular; Tight junction; Tumor necrosis factor

Indexed keywords

AMILORIDE; CHLORIDE ION; SODIUM ION; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL STRAIN CACO 2; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; SODIUM CONDUCTANCE; SODIUM TRANSPORT; TIGHT JUNCTION;

CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHLORIDES; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; EPITHELIAL CELLS; HUMANS; INTESTINAL MUCOSA; SODIUM; TIGHT JUNCTIONS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032005048     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900333     Document Type: Article

References (71)

1. Andrieu, N., Salvayre, R., Levade, T. 1996. Comparative study of the metabolic pools of Sphingomyelin and phosphatidylcholine sensitive to tumor necrosis factor. Eur. J. Biochem. 236:738-745
2. Artursson, P., Ungell, A.L., Lofroth, J.E. 1993. Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments. Pharm. Res. 10:1123-1129
3. Balaban, R.S., Mandel, L.J., Benos, D.J. 1979. On the cross-reactivity of amiloride and 2,4,6 triaminopyrimidine (TAP) for the cellular entry and tight junctional cation permeation pathways in epithelial. J. Membrane Biol. 49:363-390
4. Balda, M.S., Whitney, J.A., Flores, C., Gonzalez, S., Cereijido, M., Matter, K. 1996. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J. Cell Biol. 134:1031-1049
5. Barry, P.H. 1989. Ionic permeation mechanisms in epithelia: biionic potentials, dilution potentials, conductance and streaming potentials. Methods in Enzymology 171:678-715
6. +-selective channel in colonic carcinoma cell line: CACO-2 is activated with membrane stretch. BBA. 1069:267-272
7. Bear, C.E., Reyes, E. 1992. cAMP-activated chloride conductance in the colonic cell line. Am. J. Physiol. 262:C251-C256
8. Braegger, C.P., Nicholls, S., Murch, S.H., Stephens, S., MacDonald, T.T. 1992. Tumor necrosis factor alpha in stool as a marker of intestinal inflammation. Lancet 339:89-91
9. Breese, E.J., Michie, C.J., Nicholls, S.W., Murch, S.H., Williams, C.B., Domizio, P., Walker-Smith, J.A., Mac Donald, T.T. 1994. Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 106:1455-1466
10. Burton, K. 1956. A study of the conditions and mechanism of the diphenylamine reaction for the color metric estimation of deoxyribonucleic acid. Biochemistry 62:315-323
11. Chan, H., Aggarwal, B.B. 1994. Role of tumor necrosis factor receptors in the activation of nuclear factor XB in human histiocytic lymphoma U-937 cells. J. Biol. Chem. 269:31424-31429
12. Chen, T.R. 1977. In-situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. Exp. Cell Res. 104:255-261
13. Colgan, S.P., Parkos, C.A., Matthews, J.B., D'Andrea, L., Awtrey, C.S., Lichtman, L.H., Delp-Archer, A., Madara, J.L. 1994. Interferon-γ induces a cell surface phenotype switch on T84 intestinal epithelial cells. Am. J. Physiol. 267:C402-410
14. Colgan, S.P., Resnick, M.B., Parkos, C.P., Delp-Arecher, C., McGuirk, D., Bacarra, A.E., Weller, P.F., Madara, J.L. 1994, IL-4 directly modulates function of a model human intestinal epithelium. J. Immunol. 153:2122-2129
15. Cremaschi, D., Ferguson, D.R., Hénin, S., James, P.S., Meyer, G., Smith, M.W. 1979. Postnatal development of amiloride-sensitive sodium transport in pig distal colon. J. Physiol. 292:481-494
16. Delamere, N.A., Duncan, G. 1977. A comparison of ion concentrations, potentials and conductances of amphibian, bovine and cephalod lenses. J. Physiol. 271:167-186
17. Elson, C.O. 1996. The basis of current and future therapy for inflammatory bowel disease. Am. J. Med. 100:656-662
18. Farquhar, M.G., Palade, G.E. 1965. Cell Junctions in Amphibian Skin. J. Cell Biol. 26:263-291
19. Fogh, J., Fogh, J.M., Orfeo, T. 1977. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59:221-226
20. Frizzell, R.A., Turnheim, K. 1978. Unidirectional transport by rabbit colon: II Unidirectional sodium influx and the effects of amphotericin B and amiloride. J. Membrane Biol. 40:193-211
21. Goldman, D. 1943. Potential impedance and rectification in membranes. J. Gen. Physiol. 27:37-60
22. Gorodeski, G., Peterson, D.E., De Santis, B.J., Hopfer, U. 1996. Nucleotide receptor-mediated decrease of tight-junctional permeability in cultured human cervical epithelium. Am. J. Physiol. 270:C1715-C1725
23. Grasset, E., Pinto, M., Dussaulx, E., Zweibaum, A., Desjeux, J.-F. 1984. Epithelial properties of human colonic carcinoma cell CACO-2: electrical parameters. Am. J. Physiol. 247:C260-C267
24. Hidalgo, I.J., Raub, T.J., Borchardt, R.T. 1989. Characterization of the human colonic carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96:736-749
25. Hodgkin, A.L., Katz, B. 1949. Effect of temperature on electrical activity of giant squid axon. J. Physiol. 109:240-249
26. Hollander, D., Vadheim, C.M., Brettholz, E., Petersen, G.M., Delahunty, T., Rotler, J.I. 1989. Increased intestinal permeability in patients with Crohn's disease and their relatives: A possible etiologic factor. Ann. Intern. Med. 105:883-885
27. Ijiri, K., Potten, C.S. 1983. Response of intestinal cells of differing topographical and hierarchial status to tencytotoxic drugs and five sources of radiation. Br. J. Cancer 47:175-185
28. Kagan, B.L., Baldwin, R.L., Munoz, D., Wisnieski, B. 1992. Formation of ion-permeable channels by tumor necrosis factor-α. Science 255:1427-1430
29. Kimizuka, H. 1966. Ion current and potential across membranes. J. Theor. Biol. 13:145-163
30. Kimizuka, H., Koketsu, K. 1964. Ion transport through cell membrane. J. Theor. Biol. 6(2):290-305
31. + antiporter in human fibroblasts: dissociation between intracellular alkanization and cytokine mRNA accumulation. Blood 79:2262-2266
32. Lu, S., Goough, A.W., Bobrowski, W.F., Stewart, B.H. 1996. Transport properties are not altered across CACO-2 cells with heightened TEER despite underlying physiological and ultrastructural changes. J. Pharmaceut. Sci. 85:270-273
33. Ma, T.Y., Hollander, D., Tran, L.T., Nguyen, D., Hoa, N., Bhalla, D. 1995. Cytoskeletal regulation of CACO-2 intestinal monolayer parscellular permeability. J. Cell. Physiol. 164:533-545
34. Madara, J.L., Dharmasathaphorn, K. 1985. Occluding junction structure-function relationships in a cultured epithelial monolayer. J. Cell. Biol. 101:2124-2133
35. Madara, J.L., Stafford, J. 1989. Interferon-y directly affects barrier function of cultured intestinal epithelial monolayers. J. Clin. Invest. 83:724-727
36. Madara, J.L., Stafford, J., Dharmasathaphorn, K., Carlson, S. 1987. Structural analysis of a human intestinal epithelial cell line. Gastroenterology 92:1133-1145
37. Madsen, K.L., Tavernini, M.M., Mosmann, T.R., Fedorak, R.N. 1996. IL-10 modulates ion transport in rat small intestine. Gastroenterology 111:936-944
38. Malin, M., Isolauri, E., Pikkarainen, P., Karikoski, R., Isolauri, J. 1996. Enhanced absorption of macromolecules: a secondary factor in Crohn's disease. Dig. Dis. Sci. 41:1423-1428
39. Mano, Y., Ishü. M., Okamoto, H., Igarashi, T., Koboyashi, K., Toyota, T. 1996. Effect of tumor necrosis factor on intrahepatic bile duct epithelial cells of rat liver. Hepatology 23:1602-1607
40. 1 transepithelial resistance. J. Cell Physiol. 157:519-527
41. Martí, F., Muńoz, J., Peio, M., et al. 1995. Higher cytotoxic activity and increased levels of IL-1β IL-6, and TNF-α in patients undergoing cardiopulmonary bypass. Am. J. Hematol. 49:237-239
42. McKay, D.M., Croitoru, K., Perdue, M.H. 1996. T cell-monocyte interactions regulate epithelial physiology in a coculture model of inflammation. Am. J. Physiol. 270:C418-C428
43. Mullin, J.M., Fluk, L., Kleinzeller, A. 1986. Basal-lateral transport and transcellular flux of methylα-D-glucoside across LLC-PK1 renal epithelial cells. BBA 885:233-239
44. Mullin, J.M., Laughlin, K.V., Marano, C.W., Russo, L.M., Peralta Soler, A. 1992. Modulation of tumor necrosis factor-induced increase in renal (LLC-PK1) transepithelial permeability. Am. J. Physiol. 263:F915-F924
45. Mullin, J.M., Marano, C.W., Laughlin, K.V., Nuciglio, M., Stevenson, B.R., Peralta Soler, A. 1997. Different size limitations for increased transepithelial paracellular solute flux across phorbol ester and tumor necrosis factor-treated epithelial cell sheets. J. Cell Physiol. 17:226-233
46. Mullin, J.M., McGinn, M.T. 1988. Effects of diacylglycerols on LLC-PK1 renal epithelia: similarity to phorbol ester tumor promoters. J. Cell Physiol. 134:357-366
47. Mullin, J.M., Snock, K.V. 1990. Effect of tumor necrosis factor on epithelial tight junctions and transepithelial permeability. Cancer Res. 50:2172-2176
48. Mullin, J.M., Weibel, J., Diamond, L., Kleinzeller, A. 1980. Sugar transport in LLC-PK1 renal epithelial cell line: similarity to mammalian kidney and the influence of cell density. J. Cell Physiol. 104:375-389
49. Murch, S.H., Braegger, C.P., Walker-Smith, J.A., MacDonald, T.T. 1993. Location of tumor necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease. Gut 34:1705-1709
50. Noach, A.B.J., Sakai, M., Blom-Roosemalen, C.M., de Jonge, H.R., de Boer, A.G., Breimer, D.D. 1994. Effect of anisotonic conditions on the transport of hydrophilic compounds across monolayers of human colonic cell lines. J. Pharmacol. Exp. Therapeut. 270:1373-1380
51. 1, renal epithelial cells. Am. J. Physiol. 270:F869-F879
52. BBE clones of the human intestinal cell line, Caco-2. J. Cell Sci. 102:581-600
53. Pinto, M., Robine-Leon, S., Appay, A.-D., Kedinger, M., Triadou, N., Dussaulx, E., Lacroix, B., Simon-Assmann, P., Haffen, K., Fogh, J., Zweibaum, A. 1983. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line CACO-2 in culture. Biol. Cell. 47:323-330
54. Potten, C.S., Li, Y.Q., O'Connor, P.J., Winton, D.J. 1992. A possible explanation for the differential cancer incidence in the intestine based on distribution of the cytotoxic effects of carcinogens in the murine large bowel. Carcinogenesis 13:2302-2312
55. Riddington, D.W., Venkatesh, B., Boivin, C.M., Bonser, R.S., Elliot, T.S.J., Marshall, Mountford P.J., Bion, J.F. 1996. Intestinal permeability, gastric intramucosal pH, and systemic endotoxemia in patients undergoing cardiopulmonary bypass. JAMA 275:1007-1012
56. Riley, S.A., Warhurst, G., Crowe, P.T., Turnberg, L.A. 1991. Active hexose transport across cultured human Caco-2 cells: characterisation and influence of culture conditions. BBA 1066:175-182
57. Saladik, D.T., Peralta Soler, A., Lewis, S.A., Mullin, J.M. 1995. Cell division does not increase transepithelial permeability of LLC-PK1 cell sheets. Exp. Cell Res. 220:446-455
58. Salzman, A.L., Menconi, M.J., Unno, N., Ezzell, R.M., Casey, D.M., Gonzalez, P.K., Fink, M.P. 1995. Nitric oxide dilates tight junctions and depletes ATP in cultured Caco-2Bbe intestinal epithelial monolayers. Am. J. Physiol. 268:G361-G373
59. Sategna-Guidetti, C., Pulitano, R., Fenoglio, L., Bologna, E., Manes, M., Camussi, G. 1993. Tumor necrosis factor/cachectin in Crohn's disease. Relation of Serum concentration to disease activity. Recenti Progressi in Medicina 84:93-99
60. Schneeberger, E.E., Lynch, R.A. 1992. Structure, function, and regulation of cellular tight junctions. Am. J. Physiol. 262:L647-L661
61. Sinclair, D.G., Haslam, P.L., Quinlan, G.J., Pepper, J.R., Evans, T.W. 1995. The effect of cardiopulmonary bypass on intestinal and pulmonary endothelial permeability. Chest 108:718-724
62. Stack, W.A., Keely, S.J., O'Donaghue, D.P., Baird, A.W. 1995. Immune regulation of human colonie electrolyte transport in vitro. Gut 36:395-400
63. Stenson, W.F., Easom, R.A., Riehl, T.E., Turk, J. 1993. Regulation of paracellular permeability in CACO-2 cell monolayers by protein kinase C. Am. J. Physiol. 265:G955-G962
64. Thwaites, D.T., Cavet, M., Hirst, B.H., Simmons, N.L. 1995. Angiotensin-converting enzyme (ACE) inhibitor transport in human intestinal epithelial (Caco-2) cells. Br. J. Pharmacol. 114:981-986
65. +-independent lysine transport in human intestinal Caco-2 cells. J. Membrane Biol. 151:215-224
66. Tracey, K.J., Lowry, S.F., Beutler, B., Cerami, A., Albert, J.D., Shires, G.T. 1986. Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential. J. Exp. Med 164:1368-1373
67. Unno, N., Menconi, M.J., Salzman, A., Smith, M., Hagen, S., Ge, Y., Ezzell, R.M., Fink, M.P. 1996. Hyperpermeability and ATP depletion induced by chronic hypoxia or glycolytic inhibition in Caco2BBe monolayers. Am. J. Physiol. 270:G1010-G1021
68. Van Dullemen, H.M., Van Deventer, S.J.H., Hommes, D.W., Bijl, H.A., Jansen, J., Tytgat, G.N.J., Woody, J. 1995. Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody. Gastroenterology 109:129-135
69. Wertz, I.E., Hanley, M.R. 1996. Diverse molecular provocation of programmed cell death. Trends Biochem. Sci. 21:359-364
70. Zweibaum, A., Hauri, H.-P., Sterchi, E., Chantret, I., Haffen, K., Bamat, J. 1984. Immunohistochemical evidence, obtained with monoclonal antibodies, of small intestinal brush border hydrolases in human colon cancers and foetal colons. Int. J. Cancer 34:591-598
71. Zweibaum, A., Triadou, N., Kedinger, M., Augeron, C., Robine-Leon, S., Pinto, M., Rousset, M., Haffen, K. 1983. Sucrase-isomaltase: a marker of foetal and malignant epithelial cells of the human colon. Int. J. Cancer 32:407-412