Apical Na+/H+ exchange near the base of mouse colonic crypts

American Journal of Physiology - Cell Physiology

Volumn 283, Issue 1 52-1, 2002, Pages

  Chu, Jingsong ^a   Chu, Shaoyou ^a   Montrose, Marshall H ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b Med Sci 307H ^*  (United States)

Author keywords

2 ,7 bis(2 carboxyethyl) 5(6) carboxyfluorescein; Epithelial polarity; Immunofluorescence; Intracellular pH; Laser scanning confocal microscopy; Lucifer yellow; NHE1; NHE2; NHE3; Sodium absorption

Indexed keywords

(3 METHYLSULFONYL 4 PIPERIDINOBENZOYL)GUANIDINE METHANESULFONATE; 2',7' BIS(2 CARBOXYETHYL) 5(6) CARBOXYFLUORESCEIN; CHLORIDE ION; FLUORESCEIN; HYDROGEN; LUCIFER YELLOW; SODIUM ION; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; CHLORIDE TRANSPORT; COLON; COLON MUCOSA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EPITHELIUM CELL; EXTRACELLULAR FLUID; IMMUNOHISTOCHEMISTRY; INTESTINE ABSORPTION; INTESTINE CRYPT; LAMINA PROPRIA; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; SEROSA;

ANIMALIA;

EID: 0036086460     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.01380.2000     Document Type: Article

References (59)

1. + exchange activity by Cl
2. Short-chain fatty acids stimulate active sodium and chloride absorption in vitro in the rat distal colon
3. Electrolyte transport in the mammalian colon
4. + exchangers, NHE-1 and NHE-3 of rat intestine: Expression and localization
5. + exchanger isoforms NHE2 and NHE4 in rat intestine and kidney
6. Gut instincts: Thoughts on intestinal epithelial stem cells
7. Influence of ammonia on sodium absorption in rat proximal colon
8. Nonionic diffusion of short-chain fatty acids across rat colon
9. Acidic pH of the lateral intercellular spaces of MDCK cells cultured on permeable supports
10. The sodium concentration of the lateral intercellular spaces of MDCK cells: A microspectrofluorimetric study
11. + absorption in rats by increasing NHE3 expression of the proximal colon
12. Quantitative confocal imaging along the crypt-to-surface axis of colonic crypts
13. Extracellular pH regulation in microdomains of colonic crypts: Effects of short-chain fatty acids
14. Non-ionic diffusion and carrier mediated transport drive extracellular pH regulation of mouse colonic crypts
15. Pharmacological characterization of stably transfected Na/H antiporter isoforms using amiloride analogs and a new inhibitor with anti-ischemic properties
16. Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH
17. + exchanger in colon and is increased by a low-NaCl diet
18. + exchanger isoforms NHE-1, NHE-2, and NHE-3 mRNA
19. Maintenance of acidic lateral intercellular spaces by endogenous fixed buffers in MDCK cell epithelium
20. - absorption in isolated sheep rumen mucosa
21. +-dependent fluid absorption in intact perfused rat colonic crypts
22. Maintenance and regulation of the pH microclimate at the luminal surface of the distal colon of guinea-pig
23. Trans/paracellular, surface/crypt, and epithelial/subepithelial resistances of mammalian colonic epithelia
24. Regulation of intracellular pH gradients by a short-chain fatty acid and identified Na/H exchanger isoforms
25. pH, morphology, and diffusion in lateral intercellular spaces of epithelial cell monolayers
26. NHE2 and NHE3 are human and rabbit intestinal brush-border proteins
27. Differential regulation of NHE isoforms by sodium depletion in proximal and distal segments of rat colon
28. Preparation and characterization of viable epithelial cells from rabbit distal colon
29. + exchange on the apical side of surface colonocytes using BCECF
30. Surface pH at the basolateral membrane of the caecal mucosa of guinea pig
31. + absorption of the distal rat colon is confined to surface epithelium: A voltage scanning study
32. Determination of the Na permeability of the tight junctions of MDCK cells by fluorescence microscopy
33. Diffusion of small solutes in the lateral intercellular spaces of MDCK cell epithelium grown on permeable supports
34. pH heterogeneity at intracellular and extracellular plasma membrane sites in HT29-C1 cells
35. Expression and phosphorylation of NHE1 in wild-type and transformed human and rodent fibroblasts
36. + exchange
37. - transport and cystic fibrosis transmembrane conductance regulator mRNA in human intestinal cells
38. Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine
39. + exchanger isoforms
40. Differential localization of Na/H exchanger isoforms (NHE-1 and NHE-3) in polarized epithelial cells
41. The relationship between ionizing radiation-induced apoptosis and stem cells in the small and large intestine
42. NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells
43. Characterization of apical membrane Cl-dependent Na/H exchange in crypt cells of rat distal colon
44. Chloride-dependent Na-H exchange
45. Role of Cl channels in Cl-dependent Na/H exchange
46. + exchange function is pliable in response to transepithelial gradients of propionate
47. Absorption of Na, H ions and short-chain fatty acids from the sheep colon
48. + exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion
49. + exchanger
50. + exchanger subtype 3 in various cell types
51. Short-chain fatty acids have polarized effects on sodium transport and intracellular pH in rabbit proximal colon
52. Fluid absorption in isolated perfused colonic crypts
53. A novel role for carbonic anhydrase: Cytoplasmic pH gradient dissipation in mouse small intestinal enterocytes
54. + exchanger isoform (NHE3)
55. + exchanger gene family
56. - secretion
57. Molecular physiology of vertebrate Na/H exchangers
58. Diffusion coefficients in the lateral intercellular spaces of Madin-Darby canine kidney cell epithelium determined with caged compounds
59. Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exhanger-deficient Chinese hamster ovary cells