Genetic and epigenetic alterations of the INK4a-ARF pathway in cholangiocarcinoma

Journal of Pathology

Volumn 197, Issue 5, 2002, Pages 624-631

  Tannapfel, Andrea ^a   Sommerer, Florian ^a   Benicke, Markus ^a   Weinans, Lars ^a   Katalinic, Alexander ^b   Gei, Felix ^a   Uhlmann, Dirk ^a   Hauss, Johann ^a   Wittekind, Christian ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Cholangiocarcinoma; Histopathology; k ras; Methylation; p14ARF; p16INK4a; p53; pRb; Prognosis

Indexed keywords

DNA; MESSENGER RNA; MICROSATELLITE DNA; PROTEIN P14; PROTEIN P16; PROTEIN P53; RESTRICTION ENDONUCLEASE; RETINOBLASTOMA PROTEIN;

ARTICLE; BILE DUCT CARCINOMA; CARCINOGENESIS; CONTROLLED STUDY; CORRELATION FUNCTION; DISSECTION; DNA DETERMINATION; DNA METHYLATION; DNA SEQUENCE; EXON; GENE DELETION; GENE INACTIVATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOMA; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; PROTEIN ANALYSIS; RESTRICTION MAPPING; RNA TRANSCRIPTION;

BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CHOLANGIOCARCINOMA; CHROMOSOMES, HUMAN, PAIR 9; DNA METHYLATION; DNA, NEOPLASM; GENES, P16; GENES, P53; GENES, RAS; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; NEOPLASM PROTEINS; ODDS RATIO; PROGNOSIS; RETINOBLASTOMA PROTEIN; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 0036056617     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1139     Document Type: Article

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