In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model

Gene Therapy

Volumn 9, Issue 16, 2002, Pages 1055-1064

  Hanazono, Y ^a   Nagashima, T ^b   Takatoku, M ^a   Shibata, H ^c   Ageyama, N ^c   Asano, T ^a   Ueda, Y ^b   Dunbar, C E ^d   Kume, A ^a   Terao, K ^c   Hasegawa, M ^b   Ozawa, K ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b DNAVEC Research Inc   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Gene therapy; Hematopoietic stem cell; In vivo expansion; Nonhuman primate; Retroviral vector; Selective amplifier gene; Transplantation

Indexed keywords

CD34 ANTIGEN; CHIMERIC PROTEIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; HORMONE BINDING PROTEIN; HYDROXYTAMOXIFEN; RETROVIRUS VECTOR; TAMOXIFEN; TAMOXIFEN DERIVATIVE; TOREMIFENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE THERAPY; GENE TRANSFER; GENETIC CODE; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR CLONING; MONKEY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROGENY; PROVIRUS; TRANSPLANTATION;

ANIMALS; ANTIGENS, CD34; CELL DIVISION; FEMALE; GENE AMPLIFICATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC MARKERS; GENETIC VECTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MACACA FASCICULARIS; MALE; RECEPTORS, ESTROGEN; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; RETROVIRIDAE;

ANIMALIA; MACACA FASCICULARIS; PRIMATES; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 0036056412     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301781     Document Type: Article

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