N-oxidative transformation of free and N-substituted amine functions by cytochrome P450 as means of bioactivation and detoxication

Drug Metabolism Reviews

Volumn 34, Issue 3, 2002, Pages 451-477

  Hlavica, Peter ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

N Oxygenation; Nitrogen centers; Oxenoid peroxidative pathways

Indexed keywords

AMINE; CARBON; CYTOCHROME P450; HEMOPROTEIN; HYDROGEN; HYDROPEROXIDE; IRON DERIVATIVE; ISOENZYME; NITROGEN; OXIDIZING AGENT; RECOMBINANT PROTEIN; IRON; MIXED FUNCTION OXIDASE; OXYGEN; PEROXYGENASE;

CHEMICAL MODIFICATION; CONFERENCE PAPER; DEALKYLATION; DETOXIFICATION; ELECTRON TRANSPORT; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; IMMUNOCHEMISTRY; NONHUMAN; OXIDATION; ANIMAL; BIOTRANSFORMATION; LIVER MICROSOME; METABOLISM; OXIDATION REDUCTION REACTION; PH; REVIEW;

AMINES; ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROGEN-ION CONCENTRATION; IRON; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NITROGEN; OXIDATION-REDUCTION; OXYGEN;

EID: 0036039362     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-120005646     Document Type: Conference Paper

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