-
1
-
-
0020073188
-
Mechanistic studies on C-19 demethylation in oestrogen biosynthesis
-
Akhtar M, Calder MR, Corina DL and Wright JN (1982) Mechanistic studies on C-19 demethylation in oestrogen biosynthesis. Biochem J 201:569-580.
-
(1982)
Biochem J
, vol.201
, pp. 569-580
-
-
Akhtar, M.1
Calder, M.R.2
Corina, D.L.3
Wright, J.N.4
-
2
-
-
0023182989
-
Vasoactivity of arachidonic acid epoxides
-
Carroll MA, Schwartzman M, Capdevila J, Falok JR and McGiff JC (1987) Vasoactivity of arachidonic acid epoxides. Eur J Pharmacol 138:281-283.
-
(1987)
Eur J Pharmacol
, vol.138
, pp. 281-283
-
-
Carroll, M.A.1
Schwartzman, M.2
Capdevila, J.3
Falok, J.R.4
McGiff, J.C.5
-
4
-
-
0018076222
-
Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate
-
Dahl GA, Miller J and Miller EC (1978) Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate. Cancer Res 38:3793-3804.
-
(1978)
Cancer Res
, vol.38
, pp. 3793-3804
-
-
Dahl, G.A.1
Miller, J.2
Miller, E.C.3
-
5
-
-
0018139858
-
Regio-and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA
-
Deutsch J, Leutz JC, Yang SK, Gelboin HV, Chiang YL, Vatsis KP and Coon MJ (1978) Regio-and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA. Proc Natl Acad Sci USA 75:3123-3127.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 3123-3127
-
-
Deutsch, J.1
Leutz, J.C.2
Yang, S.K.3
Gelboin, H.V.4
Chiang, Y.L.5
Vatsis, K.P.6
Coon, M.J.7
-
7
-
-
0022557419
-
Biological strategies for the manipulation of dioxygen: The chemistry of cytochrome P-450
-
Groves JT (1986) Biological strategies for the manipulation of dioxygen: The chemistry of cytochrome P-450. Ann NY Acad Sci 471:99-107.
-
(1986)
Ann NY Acad Sci
, vol.471
, pp. 99-107
-
-
Groves, J.T.1
-
8
-
-
0017800253
-
Aliphatic hydroxylation by highly purified liver microsomal cytochrome P-450: Evidence for a carbon radical intermediate
-
Groves JT, McClusky GA, White RE and Coon MJ (1978) Aliphatic hydroxylation by highly purified liver microsomal cytochrome P-450: Evidence for a carbon radical intermediate. Biochem Biophys Res Commun 81:154-160.
-
(1978)
Biochem Biophys Res Commun
, vol.81
, pp. 154-160
-
-
Groves, J.T.1
McClusky, G.A.2
White, R.E.3
Coon, M.J.4
-
9
-
-
0026063020
-
Enzymatic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadcnosine
-
Guengerich FP, and Kim D-H (1991) Enzymatic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadcnosine. Chem Res Toxicol 4:413-421.
-
(1991)
Chem Res Toxicol
, vol.4
, pp. 413-421
-
-
Guengerich, F.P.1
Kim, D.-H.2
-
10
-
-
0025307009
-
Mechanisms of cytochrome P-450 catalysis
-
Guengerich FP and Macdonald TL (1990) Mechanisms of cytochrome P-450 catalysis. FASEB J 4:2453-2459.
-
(1990)
FASEB J
, vol.4
, pp. 2453-2459
-
-
Guengerich, F.P.1
Macdonald, T.L.2
-
11
-
-
0001541099
-
Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: Possible role of the hydroxy amino acid in oxygen activation
-
Imai M, Shimada H, Watanabe Y, Matsushima-Hibiya Y, Makino R, Koga H, Horiuchi T and Ishimura Y (1989) Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: Possible role of the hydroxy amino acid in oxygen activation. Proc Natl Acad Sci USA 86:7823-7827.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7823-7827
-
-
Imai, M.1
Shimada, H.2
Watanabe, Y.3
Matsushima-Hibiya, Y.4
Makino, R.5
Koga, H.6
Horiuchi, T.7
Ishimura, Y.8
-
12
-
-
0028986232
-
Role of Thr-252 in cytochrome P450cam: A study with unnatural amino acid mutagenesis
-
Kimata Y, Shimada H, Hirose T and Ishimura T (1995) Role of Thr-252 in cytochrome P450cam: A study with unnatural amino acid mutagenesis. Biochem Biophys Res Commun 208:96-102.
-
(1995)
Biochem Biophys Res Commun
, vol.208
, pp. 96-102
-
-
Kimata, Y.1
Shimada, H.2
Hirose, T.3
Ishimura, T.4
-
13
-
-
0030882878
-
Metabolic activation of trans-4-hydroxy-2-nonenal, a toxic product of membrane lipid peroxidation and inhibitor of P450 cytochromes
-
Kuo C-L, Vaz ADN and Coon MJ (1997) Metabolic activation of trans-4-hydroxy-2-nonenal, a toxic product of membrane lipid peroxidation and inhibitor of P450 cytochromes. J Biol Chem 272:22611-22616.
-
(1997)
J Biol Chem
, vol.272
, pp. 22611-22616
-
-
Kuo, C.-L.1
Vaz, A.D.N.2
Coon, M.J.3
-
14
-
-
0024832753
-
A conserved residue of cytochrome-P-450 is involved in heme-oxygen stability and activation
-
Martinis SA, Atkins WM, Stayton PS and Sligar SG (1989) A conserved residue of cytochrome-P-450 is involved in heme-oxygen stability and activation. J Am Chem Soc 111:9252-9253.
-
(1989)
J Am Chem Soc
, vol.111
, pp. 9252-9253
-
-
Martinis, S.A.1
Atkins, W.M.2
Stayton, P.S.3
Sligar, S.G.4
-
15
-
-
0017724462
-
Phenytoin teratogenesis: Correlation between embryopathic effect and covalent binding of putative arene oxide metabolite in gestational tissue
-
Martz F, Faillinger C and Blake DA (1977) Phenytoin teratogenesis: Correlation between embryopathic effect and covalent binding of putative arene oxide metabolite in gestational tissue. J Pharmacol Exp Ther 203:231-239.
-
(1977)
J Pharmacol Exp Ther
, vol.203
, pp. 231-239
-
-
Martz, F.1
Faillinger, C.2
Blake, D.A.3
-
16
-
-
0017150474
-
Metabolic activation of furosemide to a chemically reactive, hepatotoxic metabolite
-
Mitchell JR, Nelson WL, Potter WZ, Sasame HA and Jollow DL (1976) Metabolic activation of furosemide to a chemically reactive, hepatotoxic metabolite. J Pharmacol Exp Ther 199:41-52.
-
(1976)
J Pharmacol Exp Ther
, vol.199
, pp. 41-52
-
-
Mitchell, J.R.1
Nelson, W.L.2
Potter, W.Z.3
Sasame, H.A.4
Jollow, D.L.5
-
17
-
-
0026352457
-
Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala
-
Raag R, Martinis SA. Sligar SG and Poulos TL (1991) Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala. Biochemistry 30:11420-11429.
-
(1991)
Biochemistry
, vol.30
, pp. 11420-11429
-
-
Raag, R.1
Martinis, S.A.2
Sligar, S.G.3
Poulos, T.L.4
-
18
-
-
0029918184
-
Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral
-
Raner GM, Vaz ADN and Coon MJ (1996) Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral. Mol Pharmacol 49:515-522.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 515-522
-
-
Raner, G.M.1
Vaz, A.D.N.2
Coon, M.J.3
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