Induction of the IFN-γ gene and protein is linked to the establishment of cell polarity in a porcine epithelial cell line

Experimental Cell Research

Volumn 280, Issue 1, 2002, Pages 33-44

  Marcelo, Paulo ^a   Lefèvre, François ^a  

^a INRA Institut National de la Recherche Agronomique   (France)

Author keywords

Cell polarization; Epithelial cell; Interferon gamma; Phorbol ester; Pig; Trophectoderm; Trophoblast

Indexed keywords

F ACTIN; GAMMA INTERFERON; MESSENGER RNA; OCCLUDIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN ZO1;

ANIMAL CELL; ARTICLE; CELL LINE; CELL POLARITY; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTRIC RESISTANCE; EPITHELIUM CELL; GENE EXPRESSION; GENE INDUCTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; TIGHT JUNCTION;

SUIDAE; SUS SCROFA;

EID: 0036031831     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2002.5619     Document Type: Article

References (52)

1. Rodriguez-Boulan, E., and Nelson, W. J. (1989). Morphogenesis of the polarized epithelial cell phenotype. Science 245, 718-725.
2. Drubin, D. G., and Nelson, W. J. (1996). Origins of cell polarity. Cell 84, 335-344.
3. Cereijido, M., Valdes, J., Shoshani, L., and Contreras, R. G. (1998). Role of tight junctions in establishing and maintaining cell polarity. Annu. Rev. Physiol. 60, 161-177.
4. Stevenson, B. R., and Keon, B. H. (1998). The tight junction: Morphology to molecules. Annu. Rev. Cell. Dev. Biol. 14, 89-109.
5. Kirkpatrick, C., and Peifer, M. (1995). Not just glue: Cell-cell junctions as cellular signaling centers. Curr. Opin. Genet. Dev. 5, 56-65.
6. Tsukita, S., Furuse, M., and Itoh, M. (1999). Structural and signalling molecules come together at tight junctions. Curr. Opin. Cell Biol. 11, 628-633.
7. Zahraoui, A., Louvard, D., and Galli, T. (2000). Tight junction, a platform for trafficking and signaling protein complexes. J. Cell Biol. 151, F31-36.
8. Ben-Ze'ev, A., Shtutman, M., and Zhurinsky, J. (2000). The integration of cell adhesion with gene expression: The role of beta-catenin. Exp. Cell Res. 261, 75-82.
9. Sharpe, C., Lawrence, N., and Martinez Arias, A. (2001). Wnt signalling: A theme with nuclear variations. BioEssays 23, 311-318.
10. He, T. C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B., and Kinzler, K. W. (1998). Identification of c-MYC as a target of the APC pathway. Science 281, 1509-1512.
11. Shtutman, M., Zhurinsky, J., Simcha, I., Albanese, C., D'Amico, M., Pestell, R., and Ben-Ze'ev, A. (1999). The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc. Natl. Acad. Sci. USA 96, 5522-5527.
12. Crawford, H. C., Fingleton, B. M., Rudolph-Owen, L. A., Goss, K. J., Rubinfeld, B., Polakis, P., and Matrisian, L. M. (1999). The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. Oncogene 18, 2883-2891.
13. Billiau, A. (1996). Interferon-gamma: biology and role in pathogenesis. Adv. Immunol. 62, 61-130.
14. Avni, O., and Rao, A. (2000). T cell differentiation: A mechanistic view. Curr. Opin. Immunol. 12, 654-659.
15. Glimcher, L. H., and Murphy, K. M. (2000). Lineage commitment in the immune system: The T helper lymphocyte grows up. Genes Dev. 14, 1693-1711.
16. Murphy, K. M., Ouyang, W., Farrar, J. D., Yang, J., Ranganath, S., Asnagli, H., Afkarian, M., and Murphy, T. L. (2000). Signaling and transcription in T helper development. Annu. Rev. Immunol. 18, 451-494.
17. Lefèvre, F., Martinat-Botté, F., Guillomot, M., Zouari, K., Charley, B., and La Bonnardière, C. (1990). Interferon-gamma gene and protein are spontaneously expressed by the porcine trophectoderm early in gestation. Eur. J. Immunol. 20, 2485-2490.
18. La Bonnardière, C., Martinat-Botté, F., Terqui, M., Lefèvre, F., Zouari, K., Martal, J., and Bazer, F. W. (1991). Production of two species of interferon by Large White and Meishan pig conceptuses during the peri-attachment period. J. Reprod. Fertil. 91, 469-478.
19. Fleming, T. P., Ghassemifar, M. R., and Sheth, B. (2000). Junctional complexes in the early mammalian embryo. Semin. Reprod. Med. 18, 185-193.
20. Lefèvre, F., Martinat-Botté, F., Locatelli, A., Niu, P.-D., Terqui, M., and La Bonnardière, C. (1998). Intrauterine infusion of high doses of pig trophoblast interferons has no antiluteolytic effect in cyclic gilts. Biol. Reprod. 58, 1026-1031.
21. La Bonnardière, C., Fléchon, J. E., Battegay, S., Fléchon, B., Degrouard, J., and Lefèvre, F. (2002). Polarised trophoblastic cell lines spontaneously secrete IFN-gamma. Placenta, in press.
22. Whyte, A., Bacon, M., and Ellis, S. (1984). A monoclonal antibody to an antigen present on the microvillous membrane of the trophectoderm of the preimplantation blastocyst of the pig. J. Reprod. Fertil. 71, 599-605.
23. Balda, M. S., Anderson, J. M., and Matter, K. (1996). The SH3 domain of the tight junction protein ZO-1 binds to a serine protein kinase that phosphorylates a region C-terminal to this domain. FEBS Lett. 399, 326-332.
24. Anderson, J. M., Stevenson, B. R., Jesaitis, L. A., Goodenough, D. A., and Mooseker, M. S. (1988). Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. J. Cell Biol. 106, 1141-1149.
25. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). "Molecular Cloning: A Laboratory Manual." Cold Spring Harbor, NY.
26. Stevenson, B. R., Siliciano, J. D., Mooseker, M. S., and Good-enough, D. A. (1986). Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103, 755-766.
27. McCarthy, K. M., Skare, I. B., Stankewich, M. C., Furuse, M., Tsukita, S., Rogers, R. A., Lynch, R. D., and Schneeberger, E. E. (1996). Occludin is a functional component of the tight junction. J. Cell Sci. 109, 2287-2298.
28. Bamforth, S. D., Kniesel, U., Wolburg, H., Engelhardt, B., and Risau, W. (1999). A dominant mutant of occludin disrupts tight junction structure and function. J. Cell Sci. 112, 1879-1888.
29. Geiger, B., and Ayalon, O. (1992). Cadherins. Annu. Rev. Cell Biol. 8, 307-332.
30. Lewis, S. A., Berg, J. R., and Kleine, T. J. (1995). Modulation of epithelial permeability by extracellular macromolecules. Physiol. Rev. 75, 561-589.
31. Madara, J. L. (1987). Intestinal absorptive cell tight junctions are linked to cytoskeleton. Am. J. Physiol. 253, C171-175.
32. Itoh, M., Nagafuchi, A., Moroi, S., and Tsukita, S. (1997). Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J. Cell Biol. 138, 181-192.
33. Fanning, A. S., Jameson, B. J., Jesaitis, L. A., and Anderson, J. M. (1998). The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J. Biol. Chem. 273, 29745-29753.
34. Wittchen, E. S., Haskins, J., and Stevenson, B. R. (1999). Protein interactions at the tight junction. Actin has multiple binding partners, and zo-1 forms independent complexes with zo-2 and zo-3. J. Biol. Chem. 274, 35179-35185.
35. Lefèvre, F., Boulay, V., and La Bonnardière, C. (1991). Trophoblastic and immune interferon-gamma are expressed from the same gene in the pig. J. Interferon Res. 11(Suppl. 1), S143.
36. Lefèvre, F., Bernoin, M., and La bonnardière, C. (1996). Regulatory sequences involved in trophoblast-specific expression of the inerferon-gamma gene. Eur. Cytokine Network 7, 528.
37. Mullin, J. M., Kampherstein, J. A., Laughlin, K. V., Saladik, D. T., and Soler, A. P. (1997). Transepithelial paracellular leakiness induced by chronic phorbol ester exposure correlates with polyp-like foci and redistribution of protein kinase C-alpha. Carcinogenesis 18, 2339-2345.
38. Clarke, H., Marano, C. W., Peralta Soler, A., and Mullin, J. M. (2000). Modification of tight junction function by protein kinase C isoforms. Adv. Drug Deliv. Rev. 41, 283-301.
39. Citi, S., and Denisenko, N. (1995). Phosphorylation of the tight junction protein cingulin and the effects of protein kinase inhibitors and activators in MDCK epithelial cells. J. Cell Sci. 108, 2917-2926.
40. Stroband, H. W., and Van der Lende, T. (1990). Embryonic and uterine development during early pregnancy in pigs. J. Reprod. Fertil. Suppl. 40, 261-277.
41. Geisert, R. D., and Yelich, J. V. (1997). Regulation of conceptus development and attachment in pigs. J. Reprod. Fertil. Suppl. 52, 133-149.
42. Geisert, R. D., Brookbank, J. W., Roberts, R. M., and Bazer, F. W. (1982). Establishment of pregnancy in the pig: II. Cellular remodeling of the porcine blastocyst during elongation on day 12 of pregnancy. Biol. Reprod. 27, 941-955.
43. Mattson, B. A., Overstrom, E. W., and Albertini, D. F. (1990). Transitions in trophectoderm cellular shape and cytoskeletal organization in the elongating pig blastocyst. Biol. Reprod. 42, 195-205.
44. Gutierrez, J. A., Ertsey, R., Scavo, L. M., Collins, E., and Dobbs, L. G. (1999). Mechanical distention modulates alveolar epithelial cell phenotypic expression by transcriptional regulation. Am. J. Respir. Cell Mol. Biol. 21, 223-229.
45. Vlahakis, N. E., Schroeder, M. A., Limper, A. H., and Hubmayr, R. D. (1999). Stretch induces cytokine release by alveolar epithelial cells in vitro. Am. J. Physiol. 277, L167-173.
46. Hirokawa, M., Miura, S., Kishikawa, H., Yoshida, H., Nakamizo, H., Higuchi, H., Nakatsumi, R. C., Suzuki, H., Saito, H., and Ishii, H. (2001). Loading of mechanical pressure activates mitogen-activated protein kinase and early immediate gene in intestinal epithelial cells. Dig. Dis. Sci. 46, 1993-2003.
47. Yamamoto, H., Teramoto, H., Uetani, K., Igawa, K., and Shimizu, E. (2001). Stretch induces a growth factor in alveolar cells via protein kinase. Respir. Physiol. 127, 105-111.
48. Tschumperlin, D. J., Shively, J. D., Swartz, M. A., Silverman, E. S., Haley, K. J., Raab, G., and Drazen, J. M. (2002). Bronchial epithelial compression regulates MAP kinase signaling and HB- EGF-like growth factor expression. Am. J. Physiol. Lung Cell Mol. Physiol. 282, L904-L911.
49. Balda, M. S., and Matter, K. (2000). The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression. EMBO J. 19, 2024-2033.
50. Vietor, I., Bader, T., Paiha, K., and Huber, L. A. (2001). Perturbation of the tight junction permeability barrier by occludin loop peptides activates beta-catenin/TCF/LEF-mediated transcription. EMBO Rep. 2, 306-312.
51. Reichert, M., Muller, T., and Hunziker, W. (2000). The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney I cells. Evidence for a role of beta-catenin/Tcf/Lef signaling. J. Biol. Chem. 275, 9492-9500.
52. Denker, B. M., and Nigam, S. K. (1998). Molecular structure and assembly of the tight junction. Am. J. Physiol. 274, F1-9.