Etiology and genetics of early-onset mood disorders

Child and Adolescent Psychiatric Clinics of North America

Volumn 11, Issue 3, 2002, Pages 499-518

  Todd, Richard D ^a   Botteron, Kelly N ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; SEROTONIN TRANSPORTER;

ADOLESCENT; ANIMAL MODEL; CAUSE OF DEATH; CHILD; CHILD PSYCHIATRY; COMORBIDITY; DEPRESSION; FAMILY HISTORY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HERITABILITY; HUMAN; MANIC DEPRESSIVE PSYCHOSIS; MENTAL DISEASE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PRIORITY JOURNAL; REVIEW; SUICIDE; TWINS; ADULT; BIPOLAR DISORDER; BRAIN; CONGENITAL MALFORMATION; GENETICS; LIMBIC SYSTEM; MAJOR DEPRESSION; MOOD DISORDER; PATHOPHYSIOLOGY; PREFRONTAL CORTEX;

ADOLESCENT; ADULT; AGE OF ONSET; BIPOLAR DISORDER; BRAIN; CHILD; DEPRESSION, INVOLUTIONAL; HUMAN; LIMBIC SYSTEM; MOOD DISORDERS; PREFRONTAL CORTEX; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; DEPRESSIVE DISORDER, MAJOR; HUMANS;

EID: 0036025233     PISSN: 10564993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-4993(02)00013-5     Document Type: Review

References (126)

1. Evidence-based health policy - Lessons from the global burden of disease study
2. Deaths and death rates for the 10 leading causes of death in specified age groups, by Hispanic origin, race for non-Hispanic population, and sex. United States 2000
3. The relation between funding by the National Institutes of Health and the burden of disease
4. Family, genetic, and imaging studies of early-onset depression
5. Genetics of early onset bipolar affective disorder: Are we making progress?
6. Stability of psychiatry diagnoses: An application to the affective disorders
7. A longitudinal twin study of 1-year prevalence of major depression in women
8. A population-based twin study of major depression in women
9. The lifetime history of major depression in women: Reliability and heritability
10. A population-based twin study of lifetime major depression in men and women
11. A registry-based twin study of depression in men
12. Major depressive disorder in a community-based twin sample - Are there different genetic and environmental contributions for men and women?
13. A controlled family history study of childhood-onset depressive disorder
14. Affective disorders in first-degree relatives and adolescent bipolar, unipolar and normal controls
15. Early onset psychiatry disorder in high risk children and increased familial morbidity
16. The familial transmission of bipolar illness
17. Genetic studies of affective disorders: Should we be starting with childhood onset probands?
18. Psychiatric diagnoses in the child and adolescent members of extended families identified through bipolar affective disorder probands
19. Prevalence of affective disorder in the child and adolescent offspring of a single kindred: A pilot study
20. Psychiatric disorders in the relatives of probands with affective disorders
21. A case-control family history study of depression in adolescents
22. Psychiatric disorders in the relatives of depressed probands. I. Comparison of prepubertal, adolescent and early onset cases
23. Increased prevalence and earlier onset of mood disorders among relatives of prepubertal versus adult probands
24. Depressed adolescents grown up
25. Children with prepubertal-onset major depressive disorder and anxiety grown up
26. Selecting early onset MDD probands for genetic studies: Results from a longitudinal high-risk study
27. Adolescent depressive symptoms as predictors of adult depression: Moodiness or mood disorder?
28. Childhood and adolescent depression: A review of the past 10 years. Part I
29. Rate and predictors of prepubertal bipolarity during follow-up of 6- to 12-year-old depressed children
30. Reliability of the Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) mania and rapid cycling sections
31. The course of major depressive disorder in adolescents: I. Recovery and risk of manic switching in a follow-up of psychotic and nonpsychotic subtypes
32. A twin study of depressive symptoms in childhood
33. Comorbidity of empirically based syndromes in matched general population and clinical samples
34. A twin study of inattentive, aggressive and anxious/depressed behaviors
35. Parsing pediatric bipolar disorder from its associated comorbidity with the disruptive behavior disorders
36. Diagnostic and therapeutic dilemmas in the management of pediatric-onset bipolar disorder
37. Attention deficit hyperactivity disorder with bipolar disorder: A familial subtype?
38. Attention deficit hyperactivity disorder with bipolar in girls: Further evidence for a familial subtype?
39. Comorbidity of juvenile bipolar disorder with antisocial behavior disorders
40. Bipolar and antisocial disorders among relatives of ADHD children: Parsing familial subtypes of illness
41. Comorbidity of juvenile bipolar disorder with multiple anxiety disorders
42. Genome scans for susceptibility genes in bipolar affective disorder
43. Frequency of long allele in serotonin transporter gene is increased in depressed suicide victims
44. Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders
45. Serotonin transporter gene polymorphism and antidepressant response
46. Analysis of catechol-O-methyltransferase and 5-hydroxytryptamine transporter polymorphisms in patients at risk for suicide
47. Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects
48. Ultradian rapid cycling in prepubertal and early adolescent bipolarity is not in transmission disequilibrium with val/met COMT alleles
49. Serotonin transporter gene (HTTLPR) is not in linkage disequilibrium with prepubertal and early adolescent bipolarity
50. Depression, mania and related disorders
51. Emotion in asymmetric corticolimbic networks
52. Limbic-cortical dysregulation: A proposed model of depression
53. Depression and frontal lobe disorders
54. Dopamine, schizophrenia, mania and depression: Toward a unified hypothesis of cortico-striato-pallido-thalamic function
55. Neuroimaging abnormalities in the subgenual prefrontal cortex implications for the pathophysiology of familial mood disorders
56. Baseline cerebral hypermetabolism associated with carbamazepine response, and hypometabolism with nimodipine response in mood disorders
57. Cingulate function in depression: A potential predictor of treatment response
58. Brain glucose metabolism during non-rapid eye movement sleep major depression. A positron emission tomography study
59. Changes in forebrain function from waking to REM sleep in depression: Preliminary analyses of [18F]FDG PET studies
60. Reciprocal limbic-cortical function and negative mood: Converging PET findings in depression and normal sadness
61. Brain activity during transient sadness and happiness in healthy women
62. Cerebral blood flow changes associated with attribution of emotional valence to pleasant, unpleasant, and neutral visual stimuli in a PET study of normal subjects
63. Functional MRI study of the cognitive generation of affect
64. Prefrontal dysfunction in depressed patients performing a complex planning task: A study using positron emission tomography
65. The neuromorphometry of affective disorders
66. Paralimbic frontal lobe hypometabolism in depression associated with Huntington's disease
67. Neuroimaging in psychiatry
68. Imaging in psychiatric disorders
69. The anatomy of mood disorders review of structural neuroimaging studies
70. Neuroanatomical studies of major affective disorders
71. Amygdala core nuclei volumes are decreased in recurrent major depression
72. Quantitative MRI of the hippocampus and amygdala in severe depression
73. Hippocampal/amygdala volumes in geriatric depression
74. Hippocampal volume reduction in major depression
75. Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression
76. A quantitative magnetic resonance imaging study of caudate and lenticular nucleus gray matter volume in primary unipolar major depression: Relationship to treatment response and clinical severity
77. Quantitative cerebral anatomy of the aging human brain: A cross-sectional study using magnetic resonance imaging
78. Hippocampal volume in primary unipolar major depression: A magnetic resonance imaging study
79. Structural abnormalities in brain magnetic resonance images of depressed children
80. Volumetric reduction in left subgenual prefrontal cortex in early onset depression
81. Subgenual prefrontal cortex abnormalities in mood disorders
82. Subgenual cingulate cortex volume in firstepisode psychosis
83. Subgenual prefrontal cortex reduction in first episode affective psychosis
84. Prolonged glucocorticoid exposure reduces hippocampal neuron number: Implications for aging
85. The neuroendocrinology of stress and aging: The glucocorticoid cascade hypothesis
86. Why dexamethasone resistance? Two possible neuroendocrine mechanisms
87. Neural circuits mediating stress
88. Nocturnal growth hormone secretion studies in adolescents with or without major depression re-examined: Integration of adult clinical follow-up data
89. Low growth hormone response to growth hormone-releasing hormone in child depression
90. Biological studies in depressed children and adolescents
91. Are child-, adolescent-, and adult-onset depression one and the same disorder?
92. Preliminary study of magnetic resonance imaging characteristics in 8- to 16-year-olds with mania
93. A magnetic resonance imaging study of thalamic area in adolescent patients with either schizophrenia or bipolar disorder as compared to healthy controls
94. An MRI study of adolescent patients with either schizophrenia or bipolar disorder as compared to healthy control subjects
95. Anatomic brain magnetic resonance imaging (MRI) in pediatric bipolar disorder (BPD)
96. Neurobiological characterization of children at risk for bipolar disorder (BPD)
97. Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder
98. Proton MR spectroscopy in children with bipolar affective disorder: Preliminary observations
99. Regional brain function, emotion and disorders of emotion
100. Hemispheric asymmetry in the expression of positive and negative emotions
101. Pathophysiology of secondary depressions in the elderly
102. A magnetic resonance imaging investigation into mood disorders, multiple sclerosis: A pilot study
103. Emotion, decision making and the orbitofrontal cortex
104. Individuals with sociopathic behavior caused by frontal damage fail to respond autonomically to social stimuli
105. Reward fails to alter response bias in depression
106. Glial reduction in the subgenual prefrontal cortex in mood disorders
107. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression
108. Genetic control of cortical development
109. Imaging as a tool in exploring the neurodevelopment and genetics of schizophrenia
110. The Maudsley family study I: Structural brain changes on magnetic resonance imaging in familial schizophrenia
111. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia
112. Are the brains of monozygotic twins similar? A three-dimensional MR study
113. Genetic variability of human brain size and cortical gyral patterns
114. Surface area of human cerebral cortex and its gross morphological subdivisions: In vivo measurements in monozygotic twins suggest differential hemisphere effects of genetic factors
115. Evidence for heritability of brain structure in elderly male twins
116. A twin MRI study of size variations in human brain
117. Statistical sulcal shape comparisons: Application to the detection of genetic encoding of the central sulcus shape
118. Heritability of adolescent onset major depressive disorder: A longitudinal perspective
119. Familiality and heritability of subtypes of ADHD in a population sample of female twins
120. Latent class analysis of ADHD and comorbid symptoms in a population sample of adolescent female twins
121. Heritability of human brain morphometry
122. An epidemiological twin study of prefrontal neuromorphometry in early onset depression
123. Genetic analysis of major depression and prefrontal lobe volume