Up-regulation of heparin binding epidermal growth factor-like growth factor and amphiregulin expression in Helicobacter pylori-infected human gastric mucosa

Digestive and Liver Disease

Volumn 34, Issue 7, 2002, Pages 498-505

  Tuccillo, C ^a,b   Manzo, B A ^a   Nardone, G ^b   D'Argenio, G ^b   Rocco, A ^b   Di Popolo, A ^b   Valle, N Delta ^b   Staibano, S ^b   De Rosa, G ^b   Ricci, V ^c   Del Vecchio Blanco, C ^a   Zarrilli, R ^b   Romanol, M ^a,b  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

Amphiregulin; Gastric mucosa; Helicobacter pylori; Heparin binding epidermal growth factor; Proliferating cell nuclear antigen

Indexed keywords

AMPHIREGULIN; CYCLINE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MESSENGER RNA; UREASE; CELL SURFACE RECEPTOR; DIPHTHERIA TOXIN RECEPTOR; GLYCOPROTEIN; GROWTH PROMOTOR; SIGNAL PEPTIDE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DYSPEPSIA; ENZYME ANALYSIS; EPITHELIUM CELL; FEMALE; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABELING INDEX; MALE; MITOGENESIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH ANTRUM; STOMACH EPITHELIUM; STOMACH GLAND; STOMACH MUCOSA; TISSUE REPAIR; BIOSYNTHESIS; COMPARATIVE STUDY; EVALUATION; GASTROINTESTINAL DISEASE; GASTROINTESTINAL ENDOSCOPY; GENETICS; HOSPITALIZATION; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; STATISTICS; UPREGULATION;

ADULT; ENDOSCOPY, GASTROINTESTINAL; FEMALE; GASTRIC MUCOSA; GASTROINTESTINAL DISEASES; GLYCOPROTEINS; GROWTH SUBSTANCES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; RECEPTORS, CELL SURFACE; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; STATISTICS; UP-REGULATION;

EID: 0036020534     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1590-8658(02)80108-6     Document Type: Article

References (42)

1. Hypothesis: The changing relationships of Helicobacter pylori and humans: Implications for health and disease
2. Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer
3. Helicobacter pylori infection induces gastric cancer in mongolian gerbils
4. Molecular response of gastric epithelial cells to Helicobacter pylori-induced cell damage
5. Epidermal growth factor-related peptides and their relevance to gastrointestinal pathyphysiology
6. Transforming growth factor α protection against drug-induced damage to the rat gastric mucosa in vivo
7. Comparison between transforming growth factor alpha and epidermal growth factor in the protection of rat gastric mucosa against drug-induced injury
8. Increased gastroduodenal concentrations of transforming growth factor α in adaptation to aspirin in monkeys and rats
9. Transforming growth factors and related peptides in gastrointestinal neoplasia
10. Differential expression of epidermal growth factor-related proteins in human colorectal tumors
11. Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma
12. Expression of amphiregulin, a novel gene of the epidermal growth factor family, in human gastric carcinomas
13. Helicobacter pylori upregulates expression of epidermal growth factor-related peptides, but inhibits their proliferative effect in MKN 28 gastric mucosal cells
14. Decreased gastroduodenal mucosal concentration of transforming growth factor α in Helicobacter pylori-infected dyspeptic patients
15. Decreased expression of epidermal growth factor receptor and mRNA of its ligands in Helicobacter pylori-infected gastric mucosa
16. Structure of the human gene for the proliferating cell nuclear antigen
17. Increased COX-2, but not COX-1, mRNA expression in Helicobacter pylori gastritis
18. Activation of fetal promoters of insulin-like growth factor-II gene in hepatitis C virus-related chronic hepatitis, cirrhosis and hepatocellular carcinoma
19. Effect of Helicobacter pylori infection and its eradication on cell proliferation, DNA status, and oncogene expression in patients with chronic gastritis
20. The value of PCNA and AgNOR staining in endoscopic biopsies of gastric mucosa
21. Voyage of Helicobacter pylori in human stomach: Odyssey of a bacterium
22. Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: Role of VacA and CagA
23. + strains and dissociation of gastric epithelial cell proliferation from apoptosis
24. Response to and expression of amphiregulin by ovarian carcinoma and normal ovarian surface epithelial cells: Nuclear localization of endogenous amphiregulin
25. Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancers
26. Nuclear targeting by growth factors, cytokines, and their receptors: A role in signaling?
27. cDNA array analysis of cag pathogenicity island-associated Helicobacter pylori epithelial cell response genes
28. Mechanisms involved in the development of hypochlorhydria and pangastritis in Helicobacter pylori infection
29. Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection
30. Helicobacter pylori causes hyperproliferation of the gastric epithelium: Pre- and post-eradication indices of proliferating cell nuclear antigen
31. Helicobacter pylori alters gastric epithelial cell cycle events and gastrin secretion in Mongolian gerbils
32. Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer
33. Induction of heparin-binding epidermal growth factor-like growth factor and amphiregulin mRNAs by gastrin in the rat stomach
34. Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor
35. Cyclo-oxygenase enzymes. Structural basis for selective inhibition of cyclo-oxygenases by anti-inflammatory agents
36. Helicobacter pylori up-regulates cyclooxygenase-2 mRNA expression and prostaglandin E2 synthesis in MKN 28 gastric mucosal cells in vitro
37. Cyclooxygenase-2 expression in gastric antral mucosa before and after eradication of Helicobacter pylori infection
38. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase-2 in Helicobacter pylori gastritis
39. The role of cyclooxygenases in inflammation, cancer, and development
40. Carcinogenesis, apoptosis and cell proliferation
41. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa
42. Combinations for cancer prevention