Activation of fetal promoters of insulinlike growth factor II gene in hepatitis C virus-related chronic hepatitis, cirrhosis, and hepatocellular carcinoma

Hepatology

Volumn 23, Issue 6, 1996, Pages 1304-1312

  Nardone, Gerardo ^a,b   Romano, Marco ^a,c   Calabro, Antonio ^e   Pedone, Paolo V ^a   De Sio, Ilario ^c   Persico, Marcello ^d   Budillon, Gabriele ^b   Bruni, Carmelo B ^a   Riccio, Andrea ^a   Zarrilli, Raffaele ^a,b  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c Dipto Internistica Clin e Sperim   (Italy)

^d Ist Med Gen E Metodologia Clin   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; HEPATITIS C ANTIBODY; MESSENGER RNA; SOMATOMEDIN B;

ADULT; AGED; ANTIBODY DETECTION; ANTIGEN EXPRESSION; ARTICLE; CHRONIC ACTIVE HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FETUS; GENE ACTIVATION; GENE EXPRESSION; HEPATITIS C VIRUS; HISTOLOGY; HUMAN; HUMAN TISSUE; LIVER BIOPSY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MALE; MITOSIS RATE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 15844368831     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v23.pm0008675143     Document Type: Article

References (18)

1. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989;244:359-362.
2. Alter MJ, Purcell RH, Shih JW, Melpolder JC, Houghton M, Choo Q-L, Kuo G. Detection of antibodies to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med 1989;321:1494-1500.
3. Tremolada F, Casarin C, Alberti A, Drago C, Tagger A, Ribero ML, Realdi G. Long-term follow-up of non-A, non-B (type C) posttransfusion hepatitis. J Hepatol 1992;16:273-281.
4. Viladomiu L, Genescà J, Estebàn JI, Allende H, Gonzales A, Lopez TJ, Esteban R, et al. Interpheron-alpha in acute posttransfusion hepatitis C: a randomized, controlled trial. HEPATOLOGY 1992;15:767-769.
5. Colombo M, Kuo G, Choo QL, Donato MF, Del Ninno E, Tommasini MA, Dioguardi, et al. Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet 1989;i:1006-1008.
6. Bruix J, Barrera JM, Calvet X, Ercilla G, Costa J, Sanchez-Tapias JM, Ventura M, et al. Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosis. Lancet 1989;ii:1004-1006.
7. Caporaso N, Romano M, Marmo R, de Sio I, Morisco F, Minerva A, Coltorti M. Hepatitis C virus infection is an additive risk factor for development of hepatocellular carcinoma in patients with liver cirrhosis. J Hepatol 1991;12:367-371.
8. Ken MC, Popper H. Relationship between hepatocellular carcinoma and cirrhosis. Semin Liver Dis 1984;4:136-146.
9. Chisari FV, Klopchin K, Moriyama T, Pasquinelli C, Dunsford HA, Sell S, Pinkert CA, et al. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 1989;59:1145-1156.
10. 1-antitrypsin transgenic mice: histopathological and DNA ploidy studies. HEPATOLOGY 1994;19:389-397.
11. Humbel RE. Insulin-like growth factors I and II. Eur J Biochem 1990;190:445-462.
12. Zarrilli R, Bruni CB, Riccio A. Multiple levels of control of the insulin-like growth factor gene expression. Mol Cell Endocrinol 1994;101:R1-R14.
13. DeChiara TM, Esfradiatis A, Robertson EJ. A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 1990;345:78-80.
14. Liu J-P, Baker J, Perkins AS, Robertson EJ, Esfradiatis A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (IGF1r). Cell 1993;75:59-72.
15. Bell GI, Merryweather JP, Sanchez-Pescador R, Stempien MM, Priestly L, Scott J, Rail LB. Sequence of a cDNA clone encoding human preproinsulin-like growth factor II. Nature 1984;311: 775-778.
16. De Pagter-Holtuizen P, Jansen M, van Schaik FMA, van der Kammen R, Oosterwijk C, Van den Brande JL, Sussenbach JS. The human insulin-like growth factor II gene contains two development-specific promoters. FEES Lett 1987;214:259-264.
17. De Pagter-Holtuizen P, Jansen M, van der Kammen R, van Schaik FMA, Sussenbach JS. Differential expression of the human insulin-like growth factor II gene Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II associated protein. Biochim Biophys Acta 1988;950:282-295.
18. Vu TH, Hoffman AR. Promoter-specific imprinting status of the human insulin-like growth factor II gene. Nature 1994;371:714-717.