Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: In vivo studies

British Journal of Pharmacology

Volumn 135, Issue 2, 2002, Pages 344-355

  Stasch, Johannes Peter ^a   Dembowsky, Klaus ^a   Perzborn, Elisabeth ^a   Stahl, Elke ^a   Schramm, Matthias ^a  

^a BAYER AG   (Germany)

Author keywords

BAY 41 8543; Blood pressure; Cyclic GMP; Dogs; L NAME; Nitric oxide; Rats; Soluble guanylyl cyclase; VASP; YC 1

Indexed keywords

2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL] 5 MORPHOLINO 4,6 PYRIMIDINEDIAMINE; FERRIC CHLORIDE; GUANYLATE CYCLASE ACTIVATOR; N(G) NITROARGININE METHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING TIME; CARDIOVASCULAR EFFECT; CORONARY ARTERY BLOOD FLOW; DOSE RESPONSE; ENZYME ACTIVATION; FEMALE; HEART RATE; HEMODYNAMICS; HYPERTENSION; MALE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; TACHYPHYLAXIS; THROMBOSIS;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATORS; FEMALE; GUANYLATE CYCLASE; HEMODYNAMIC PROCESSES; MALE; MORPHOLINES; NITRIC OXIDE; PYRIMIDINES; RATS; RATS, INBRED SHR; RATS, WISTAR;

EID: 0036178227     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704483     Document Type: Article

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