Upregulation of EphA receptor expression in the injured adult rat spinal cord

Cell Transplantation

Volumn 11, Issue 3, 2002, Pages 229-239

  Willson, C A ^a   Irizarry Ramiacrez M ^b   Gaskins, H E ^a   Cruz Orengo, L ^b   Figueroa, J D ^b   Whittemore, S R ^a   Miranda, J D ^b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

Immunohistochemistry; Receptor tyrosine kinase; RT PCR; Spinal cord injury; Trauma

Indexed keywords

EPHRIN A RECEPTOR; EPHRIN A3 RECEPTOR; EPHRIN A4 RECEPTOR; EPHRIN A6 RECEPTOR; EPHRIN A8 RECEPTOR; EPHRIN RECEPTOR; MESSENGER RNA; RECEPTOR SUBTYPE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; EPHRIN; ISOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ASTROCYTE; CELL REGENERATION; CONFERENCE PAPER; CONTROLLED STUDY; GRAY MATTER; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOTONEURON; NERVE FIBER GROWTH; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD DORSAL HORN; SPINAL CORD INJURY; THALAMUS VENTRAL NUCLEUS; ANIMAL; ARTICLE; FEMALE; GENETICS; METABOLISM; PATHOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMALIA;

ANIMALS; EPHRINS; FEMALE; IMMUNOHISTOCHEMISTRY; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, EPH FAMILY; RNA, MESSENGER; SPINAL CORD; SPINAL CORD INJURIES; UP-REGULATION;

EID: 0035998721     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096020198389997     Document Type: Conference Paper

References (65)

1. Alterations in temporal/spatial distribution of GFAP- and vimentin-positive astrocytes after spinal cord contusion with the New York University spinal cord injury device
2. NI-35/250/nogo-a: A neurite growth inhibitor restricting structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS
3. A sensitive and reliable locomotor rating scale for open field testing in rats
4. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
5. MASCIS evaluation of open field locomotor scores: Effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study
6. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
7. Alterations of EphB2 proteins following spinal cord injury in the adult rat
8. Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism
9. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1
10. Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone
11. Cellular localization of ephrin-A2, ephrin-A5, and other functional guidance cues underlies retinotopic development across species
12. EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract
13. Astrocytic reaction after graded spinal cord compression in rats: Immunohistochemical studies on glial fibrillary acidic protein and vimentin
14. Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping
15. Roles for ephrins in positionally selective synaptogenesis between motor neurons and muscle fibers
16. Repulsive factors and axon regeneration in the CNS
17. Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system
18. Ephrin-dependent growth and pruning of hippocampal axons
19. Regulation of topographic projection in the brain: Elf-1 in the hippocamposeptal system
20. A monitored contusion model of spinal cord injury in the rat
21. Altered immunoreactivity for glial fibrillary acidic protein in astrocytes within 1h after cervical spinal cord injury
22. The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans
23. Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons
24. The Eph receptor tyrosine kinases and the ephrins-roles in nervous system development
25. Upregulation of the receptor tyrosine kinases EphA3 and EphA4 after spinal cord injury
26. Axon guidance molecules
27. Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets
28. Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control
29. Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation
30. Immunolocalization of the receptor tyrosine kinase EphA4 in the adult rat central nervous system
31. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth
32. Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord
33. Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A
34. Validation of the weight-drop contusion model in rats: A comparative study of human spinal cord injury
35. Induction of Eph B3 after spinal cord injury
36. Up-regulation of Eph tyrosine kinase receptors after excitotoxic injury in adult hippocampus
37. Differential expressions of the eph family of receptor tyrosine kinase genes (sek, elk, eck) in the developing nervous system of the mouse
38. Localization of novel receptor tyrosine kinase genes of the eph family, MDK1 and its splicing variant, in the developing mouse nervous system
39. Astrocytes and oligodendrocytes reactions after a total section of the rat spinal cord
40. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycans
41. Spinal cord contusion in the rat: Morphometric analyses of alterations in the spinal cord
42. Eph receptors and ephrins in neural development
43. The receptor tyrosine kinase, Cek8, is transiently expressed on subtypes of motoneurons in the spinal cord during development
44. The Eph receptor family: Axonal guidance by contact repulsion
45. Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors
46. Semaphorins and their receptors in olfactory axon guidance
47. Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging
48. Inhibitor of neurite outgrowth in humans
49. NPAS2: An analog of clock operative in the mammalian forebrain
50. The glial scar: Its bearing on axonal elongation and transplantation approaches to CNS repair
51. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
52. Inhibitors of neurite growth
53. Inhibitory molecules in development and regeneration
54. Identification and characterization of a bovine neurite growth inhibitor (bNI-220)
55. A role for the Eph ligand ephrin-A3 in entorhino-hippocampal axon targeting
56. The molecular biology of axon guidance
57. Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions
58. The EphA4 receptor tyrosine kinase is necessary for the guidance of nasal retinal ganglion cell axons in vitro
59. EphB3 receptor expression in the spinal cord and supraspinal nuclei of spinal cord transected rats
60. Spinal cord injury models
61. Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline
62. Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5
63. Detection of ligands in regions anatomically connected to neurons expressing the Eph receptor Bsk: Potential roles in neuron-target interaction
64. Cytoskeletal disruption following contusion injury to the rat spinal cord