Small-colony mutants of Staphylococcus aureus allow selection of gyrase-mediated resistance to dual-target fluoroquinolones

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 8, 2002, Pages 2498-2506

  Pan, Xiao Su ^a   Hamlyn, Penelope J ^a   Talens Visconti, Raquel ^a   Alovero, Fabiana L ^a   Manzo, Ruben H ^a   Fisher, L Mark ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

7 [4 (4 AMINOPHENYLSULFONYL) 1 PIPERAZINYL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 3 QUINOLINECARBOXYLIC ACID; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TRYPSIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; COAGULASE; HEMIN; MENADIONE; QUINOLONE DERIVATIVE; THYMIDINE;

ALLELE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM MUTANT; ELECTRON TRANSPORT; GENE DELETION; GENE SEQUENCE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; STAPHYLOCOCCUS AUREUS; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; METABOLISM; MICROBIOLOGICAL EXAMINATION; MUTATION;

ANTI-INFECTIVE AGENTS, FLUOROQUINOLONE; COAGULASE; DNA GYRASE; DNA TOPOISOMERASE IV; DRUG RESISTANCE, MICROBIAL; HEMIN; MICROBIAL SENSITIVITY TESTS; MUTATION; PHENOTYPE; QUINOLONES; STAPHYLOCOCCUS AUREUS; SUPPORT, NON-U.S. GOV'T; THYMIDINE; VITAMIN K 3; ANTI-INFECTIVE AGENTS; FLUOROQUINOLONES;

EID: 0035991845     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.8.2498-2506.2002     Document Type: Article

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