Modulation of gyrase-mediated DNA cleavage and cell killing by ATP

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 5, 1998, Pages 1022-1027

  Li, Tsai Kun ^a   Liu, Leroy F ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CIPROFLOXACIN; COUMAMYCIN; DNA TOPOISOMERASE (ATP HYDROLYSING); EPIPODOPHYLLOTOXIN; ETOPOSIDE; FLUOROACETIC ACID; NALIDIXIC ACID; QUINOLONE DERIVATIVE; TENIPOSIDE;

ARTICLE; BACTERICIDAL ACTIVITY; CELL DAMAGE; CELL KILLING; DNA CLEAVAGE; DNA STRAND BREAKAGE; DRUG ANTAGONISM; DRUG EFFICACY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

EID: 0031979125     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.5.1022     Document Type: Article

References (41)

1. Ali, J. A., A. P. Jackson, A. J. Howell, and A. Maxwell. 1993. The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs. Biochemistry 32:2717-2724.
2. Ali, J. A., G. Orphanides, and A. Maxwell. 1995. Nucleotide binding to the 43-kilodalton N-terminal fragment of the DNA gyrase B protein. Biochemistry 34:9801-9808.
3. Austin, C. A., K. L. Marsh, R. A. Wasserman, E. Willmore, P. J. Sayer, J. C. Wang, and L. M. Fisher. 1995. Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase II beta. J. Biol. Chem. 270:15739-15746.
4. Beck, W. T., and M. K. Danks. 1991. Mechanisms of resistance to drugs that inhibit DNA topoisomerases. Semin. Cancer Biol. 2:235-244.
5. Berger, J. M., S. J. Gamblin, S. C. Harrison, and J. C. Wang. 1996. Structure and mechanism of DNA topoisomerase II. Nature 379:225-232.
6. D'Arpa, P., C. Beardmore, and L. F. Liu. 1990. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res. 50:6919-6924.
7. Deitz, W. H., T. M. Cook, and W. A. Goss. 1966. Mechanism of action of nalidixic acid on Escherichia coli. III. Conditions required for lethality. J. Bacteriol. 91:768-773.
8. Drake, F. H., G. A. Hofmann, H. F. Bartus, M. R. Mattern, S. T. Crooke, and C. K. Mirabelli. 1989. Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II. Biochemistry 28:8154-8160.
9. Drlica, K., and R. J. Franco. 1988. Inhibitors of DNA topoisomerases. Biochemistry 27:2253-2259.
10. Gilbert, E. J., and A. Maxwell. 1994. The 24 kDa N-terminal sub-domain of the DNA gyrase B protein binds coumarin drugs. Mol. Microbiol. 12:365-373.
11. Gormley, N. A., G. Orphanides, A. Meyer, P. M. Cullis, and A. Maxwell. 1996. The interaction of coumarin antibiotics with fragments of DNA gyrase B protein. Biochemistry 35:5083-5092.
12. Helling, R. B., and J. S. Kukora. 1971. Nalidixic acid-resistant mutants of Escherichia coli deficient in isocitrate dehydrogenase. J. Bacteriol. 105:1224-1226.
13. Hooper, D. C., and J. S. Wolfson. 1988. Mode of action of the quinolone antimicrobial agents. Rev. Infect. Dis. 10:S14-S21.
14. Howard, M. T., S. H. Neece, S. W. Matson, and K. J. Kreuzer. 1994. Disruption of a topoisomerase-DNA cleavage complex by a helicase. Proc. Natl. Acad. Sci. USA 91:12031-12035.
15. Hsieh, L.-S., R. M. Burger, and K. Drlica. 1991. Bacterial DNA supercoiling and [ATP]/[ADP]: change associated with a transition to anaerobic growth. J. Mol. Biol. 219:443-450.
16. Hsieh, L.-S., J. Rouviere-Yaniv, and K. Drlica. 1991. Bacterial DNA supercoiling and [ATP]/[ADP]: changes associated with salt shock. J. Bacteriol 173:3914-3917.
17. Hughes, C. S., J. W. Shen, and J. R. Subjeck. 1989. Resistance to etoposide induced by three glucose-regulated stresses in Chinese ovary cells. Cancer Res. 49:4452-4454.
18. Kupfer, G., A. L. Bodley, and L. F. Liu. 1987. Involvement of intracellular ATP in cytotoxicity of topoisomerase II-targeting antitumor drugs. NCI Monogr. 4:37-40.
19. Lakshmi, T. M., and R. B. Helling. 1976. Selection of citrate synthase deficient in icd mutants of Escherichia coli. J. Bacteriol. 127:76-83.
20. Lindsley, J. E., and J. C. Wang. 1991. Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding. Proc. Natl. Acad. Sci. USA 88:10485-10489.
21. Lindsley, J. E., and J. C. Wang. 1993. On the coupling between ATP usage and DNA transport by yeast DNA topoisomerase II. J. Biol. Chem. 268: 8096-8104.
22. Lindsley, J. E., and J. C. Wang. 1993. Study of allosteric communication between promoters by immunotagging. Nature 361:749-750.
23. Liu, L. F. 1989. DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58:351-375.
24. Maxwell, A. 1993. The interaction between coumarin drugs and DNA gyrase. Mol. Microbiol. 9:681-668.
25. Maxwell, A., D. C. Rau, and M. Gellert. 1986. Proceedings of the fourth conversation in the discipline of biomolecular stereodynamics, p. 137-146. In R. H. Sarma and M. H. Sarma (ed.), Biomolecular stereodynamics III. Adenine Press, Albany, N.Y.
26. Menzel, R., and M. Gellert. 1994. The biochemistry and biology of DNA gyrase, p. 39-61. In L. F. Liu (ed.), Advances in pharmacology-DNA topoisomerases: biochemistry and molecular biology. Academic Press, Inc., San Diego, Calif.
27. Morrison, A., N. P. Higgins, and N. R. Cozzarelli. 1980. Interaction between DNA gyrase and its cleavage sites on DNA. J. Biol. Chem. 255:2211-2219.
28. Nelson, E. M., K. M. Tewey, and L. F. Liu. 1984. Mechanism of anti-tumor drugs: poisoning of mammalian DNA topoisomerase II on DNA by anti-tumor drug m-MASA. Proc. Natl. Acad. Sci. USA 81:1361-1365.
29. Orphanides, D., and A. Maxwell. 1994. Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprint. Nucleic Acids Res. 22:1567-1575.
30. Osheroff, N. 1986. Eucaryotic topoisomerase II: characterization of enzyme turnover. J. Biol. Chem. 261:9944-9950.
31. Roca, J., and J. C. Wang. 1992. The capture of a DNA duplex helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerase. Cell 71:833-840.
32. Roca, J., R. Ishida, J. M. Berger, T. Andoh, and J. C. Wang. 1994. Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc. Natl. Acad Sci USA 91:1781-1785.
33. Rohweer, J. M., P. R. Jensen, Y. Shinohara, P. W. Postma and H. V. Westerhoff. 1996. Changes in the cellular energy state affect the activity of the bacterial phosphotransferase system. Eur. J. Biochem. 235:225-230.
34. Schultz, P., S. Olland, P. Oudet, and R. Hancock. 1996. Structure and conformational changes of DNA topoisomerase II visualized by electron microscopy. Proc. Natl. Acad. Sci. USA 93:5936-5940.
35. Sugino, A., and N. R. Cozzarelli. 1980. The intrinsic ATPase of DNA gyrase J. Biol. Chem. 255:6299-6306.
36. Sugino, A., N. P. Higgins, P. K. Brown, C. L. Peebles, and N. R. Cozzarelli. 1978. Energy coupling in the DNA gyrase and the mechanism of action of novobiocin. Proc. Natl. Acad. Sci. USA 75:4838-4842.
37. Tamura, J. K., A. D. Bate, and M. Gellert. 1992. Slow interaction of 5′-adenylyl-β,γ-imidodiphosphate with Escherichia coli gyrase. J. Biol. Chem. 267:9214-9222.
38. Wang, J. C. 1996. DNA topoisomerases. Annu. Rev. Biochem. 65:635-692.
39. Westerhoff, H. V., M. H. O'Dea, A. Maxwell, and M. Gellert. 1988. DNA supercoiling by gyrase: a static head analysis. Cell Biophys. 12:157-181.
40. Wu, H.-Y., and L. F. Liu. 1991. DNA looping alters DNA conformation during transcription. J. Mol. Biol. 219:615-622.
41. Yamauchi, T., T. A. Raffin, P. Yang, and B. I. Sikic. 1987. Differential protective effects of varying degrees of hypoxia on the cytotoxicities of etoposide and bleomycin. Cancer Chemother. Pharmacol. 19:282-286.