gyrB-225, a mutation of DNA gyrase that compensates for topoisomerase I deficiency: Investigation of its low activity and quinolone hypersensitivity

Journal of Molecular Biology

Volumn 309, Issue 5, 2001, Pages 1219-1231

  Heddle, Jonathan G ^a   Lu, Tao ^b   Zhao, Xilin ^b   Drlica, Karl ^b   Maxwell, Anthony ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

Ciprofloxacin; Oxolinic acid; TopA

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CIPROFLOXACIN; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); OXOLINIC ACID; QUINOLONE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIOSTASIS; CARBOXY TERMINAL SEQUENCE; DNA SUPERCOILING; DRUG HYPERSENSITIVITY; DRUG MECHANISM; ENZYME DEFICIENCY; ENZYME SUBUNIT; GENE DELETION; GENE INSERTION; HYDROLYSIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING;

EID: 0035933283     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4733     Document Type: Article

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