Costimulatory molecules and autoimmune thyroid diseases

Autoimmunity

Volumn 35, Issue 3, 2002, Pages 159-167

  Salmaso, Claudia ^a   Olive, Daniel ^b   Pesce, Giampaola ^a   Bagnasco, Marcello ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b INSERM   (France)

Author keywords

Autoimmune reaction; Costimulation; Grave's disease; Hashimoto's thyroiditis

Indexed keywords

AUTOANTIGEN; B7 ANTIGEN; CD2 ANTIGEN; CD28 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; ABATACEPT; ANTIBODY CONJUGATE; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; INDUCIBLE T CELL CO STIMULATOR; INDUCIBLE T-CELL CO-STIMULATOR; LEUKOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; APOPTOSIS; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURFACE; CELLULAR IMMUNITY; CLONAL ANERGY; CYTOKINE RELEASE; DENDRITIC CELL; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HUMORAL IMMUNITY; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC INFILTRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULE; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYROID DISEASE; THYROID FOLLICLE CELL; AUTOIMMUNE THYROIDITIS; IMMUNOLOGY; PHYSIOLOGY;

ANTIGEN PRESENTATION; ANTIGENS, CD28; ANTIGENS, CD40; ANTIGENS, DIFFERENTIATION; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; GRAVES' DISEASE; HUMAN; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES; THYROIDITIS, AUTOIMMUNE; ANTIGENS, CD; GRAVES DISEASE; HUMANS; IMMUNOCONJUGATES;

EID: 0035986683     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.1080/08916930290013441     Document Type: Review

References (79)

1. CD40 and CD154 in cell-mediated immunity
2. What is the real role of CD40 in cancer immunotherapy?
3. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions
4. Help for cytotoxic-T-cell responses is mediated by CD40 signalling
5. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
6. Immunology. Licence to kill
7. 4-1BB: Still in the midst of darkness
8. Signaling takes shape in the immune system
9. Stimulation via the CD28 molecule. Regulation of signalling, cytokine production and cytokine receptor expression
10. Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T-cells
11. Negative regulation of T cell activation
12. Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2
13. B7/CD28 costimulation is essential for the homeostasis of the CD4+ CD25+ immunoregulatory T cells that control autoimmune diabetes
14. CTLA-4 in autoimmune diseases - A general susceptibility gene to autoimmunity?
15. CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease
16. PD-L2 is a second ligand for PD-1 and inhibits T cell activation
17. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
18. The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T cell function
19. Adhesion molecule expression in Graves' thyroid glands; Potential relevance of granule membrane protein (GMP-140) and intercellular adhesion molecule-1 (ICAM-1) in the homing and antigen presentation process
20. The expression of adhesion molecules in thyroid glands from patients with Graves' disease
21. Dendritic cells in various human thyroid diseases
22. Adhesion molecules from the LFA-1/ICAM-1,3 and VLA-4/VCAM-1 pathways on T lymphocytes and vascular endothelium in Graves' and Hashimoto's thyroid glands
23. Intrathyroidal dendritic cells
24. Adherence of RFD-1 positive dendritic cells to the basal surface of thyroid follicular cells in Graves' disease
25. Induction of autoimmunity with dendritic cells: Studies on thyroiditis in mice
26. Two-step development of Hashimoto-like thyroiditis in genetically autoimmune prone non-obese diabetic mice: Effects of iodine-induced cell necrosis
27. Antigen-presenting dendritic cells as regulators of the growth of thyrocytes: A role of interleukin-1beta and interleukin-6
28. Dendritic cells and class II MHC expression on thyrocytes during the autoimmune thyroid disease of the BB rat
29. Experimental autoimmune thyroiditis induced by thyroglobulin-pulsed dendritic cells
30. Cytokines, IgG subclasses and costimulation in a mouse model of thyroid autoimmunity induced by injection of fibroblasts co-expressing MHC class II and thyroid autoantigens
31. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
32. IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses
33. Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease
34. Occurrence of thyrocyte HLA class II expression in a wide variety of thyroid diseases: Relationship with lymphocytic infiltration and thyroid autoantibodies
35. Spatial correlation between thyroid epithelial cells expressing class II MHC molecules and interferon-gamma-containing lymphocytes in human thyroid autoimmune disease
36. Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells
37. Synergy in antigen presentation by thyroid epithelial cells and monocytes from patients with Graves' disease
38. Lack of B7.1/BB1 and B7.2/B70 expression on thyrocytes of patients with Graves' disease. Delivery of costimulatory signals from bystander professional antigen-presenting cells
39. Autoimmune thyroid disease: Immunological model and clinical problem
40. Autoimmune thyroid disease: Further developments in our understanding
41. Expression of the costimulatory molecule B7/BB1 in autoimmune thyroid disease
42. Antigen presentation by IFN-γ treated thyroid follicular cells inhibits IL2 and support IL4 production by B7-dependent human T cells
43. B7.1 costimulatory molecule is expressed on thyroid follicular cells in Hashimoto's thyroiditis, but not in Graves' disease
44. B7.1 and B7.2 costimulatory molecules differentially activate the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
45. Coexpression of CD40 and class II antigen HLA-DR in Graves' disease thyroid epithelial cells
46. Detection of CD40 on human thyroid follicular cells: Analysis of expression and function
47. CD40 expression in human thyroid tissue: Evidence for involvement of multiple cell types in autoimmune and neoplastic diseases
48. Human orbital fibroblasts are activated through CD40 to induce proinflammatory cytokine production
49. Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy
50. Integrin expression in thyroid cells from normal glands and nodular goiters
51. Changes in integrin and E-cadherin expression in neoplastic versus normal thyroid tissue
52. Expression of intercellular adhesion molecule-1 (ICAM-1) on thyroid epithelial cells in Hashimoto's thyroiditis but not in Graves' disease or papillary thyroid cancer
53. Expression of an intercellular adhesion molecule, ICAM-1, by human thyroid cells
54. Expression of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-3 on human thyroid epithelial cells in Graves' and Hashimoto's disease
55. Expression of intercellular adhesion molecule-1 in thyroid follicular cells in autoimmune, non-autoimmune and neoplastic diseases of the thyroid gland: Discordance with HLA
56. Thyrocyte proliferation by cellular adhesion to infiltrating lymphocytes through the intercellular adhesion molecule-1/lymphocyte function-associated antigen-1 pathway in Graves' disease
57. Functional analysis of intercellular adhesion molecule-1-expressing human thyroid cells
58. Follicular thyroid cells of autoimmune thyroiditis may coexpress ICAM-1 (CD54) and its natural ligand LFA-1 (CD11a/CD18)
59. Preliminary evidence for "aberrant" expression of the leukocyte integrin LFA1 (CD11a/CD18) on conjunctival epithelial cells of patient with mite allergy
60. Different intrathyroid expression of intercellular adhesion molecule-1 (ICAM-1) in Hashimoto's thyroiditis and Graves' disease: Analysis at mRNA level and association with B7.1 costimulatory molecule
61. Clonal analysis of T lymphocytes infiltrating the thyroid gland in Hashimoto's thyroiditis
62. Graves' disease: Phenotypic and functional analysis at the clonal level of the T-cell repertoire in peripheral blood and in thyroid
63. Enhanced production of γ-interferon by thyroid-derived T cell clones from patients with Hashimoto's thyroiditis
64. High potential to tumor necrosis factor alpha production of thyroid infiltrating T lymphocytes in Hashimoto's thyroiditis: A peculiar feature of destructive thyroid autoimmunity
65. Induction of Th1 and Th2 response: A key role for the natural immune response?
66. Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins
67. Human T-cell clones from autoimmune thyroid glands: Specific recognition of autologous thyroid cells
68. Cellular immunity in autoimmune thyroid disease
69. CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population
70. A CTLA-4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism
71. CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus
72. CTLA-4 and not CD28 is a susceptibility gene for thyroid autoantibody production
73. Cutting edge: A soluble form of CTLA-4 in patients with autoimmune thyroid disease
74. Editorial: Dying (apoptosing?) for a consensus on the Fas death pathway in the thyroid
75. Apoptosis in the pathogenesis and treatment of disease
76. Differential regulation of Fas-mediated apoptosis in both thyrocyte and lymphocyte cellular compartments correlates with opposite phenotypic manifestations of autoimmune thyroid disease
77. CD28 and apoptosis
78. Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7.1/B7.2
79. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis