Treasure hunting in a new era: Genotyping of single nucleotide polymorphisms and the search for complex disease genes by association scans

Psychiatric Genetics

Volumn 12, Issue 2, 2002, Pages 63-66

  McGinnis, Ralph ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Association; Case control; Gene mapping; Linkage disequilibrium; Power; Single nucleotide polymorphism; Transmission disequilibrium test

Indexed keywords

GENE MAPPING; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOTYPE; HUMAN; HUMAN GENETICS; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; EDITORIAL; GENETIC DISORDER; GENETIC PROCEDURES; GENETICS;

GENETIC DISEASES, INBORN; GENETIC TECHNIQUES; GENOTYPE; HUMAN; POLYMORPHISM, SINGLE NUCLEOTIDE; HUMANS;

EID: 0035986213     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041444-200206000-00002     Document Type: Review

References (11)

1. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus
2. A polymorphic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders
3. Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility
4. Hidden linkage: A comparison of the affected sib pair (ASP) test and transmission/disequilibrium test (TDT)
5. s, and the power of the TDT and affected sib-pair test
6. Power and efficiency of the TDT and case-control design for association scans
7. Linkage disequilibrium in the human genome
8. Searching for genetic determinants in the new millenium
9. The future of genetic studies of complex human diseases
10. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
11. HLA, insulin gene, and Gm associations with IDDM